Advances in Absorption and Metabolism of Folate and Its Mechanism in Layers

  • SUN Dandan ,
  • ZHANG Junmin ,
  • ZHAO Qingyu ,
  • QIN Yuchang
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  • 1. State Key Laboratory of Animal Nutrition, Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing 100193, China;
    2. Scientific Observing and Experiment Station of Animal Genetic Resources and Nutrition in North China of Ministry of Agriculture and Rural Affairs, Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing 100193, China

Received date: 2019-11-23

  Online published: 2020-06-16

Abstract

Insufficient folate intake is a global problem, and low levels of folate in the human body increase the risk of anemia, malformation, cardiovascular and cerebrovascular diseases, cancer and cognitive impairment. However, excessive intake of oxidized folic acid may cause a potential risk. The oxidized folic acid is converted into a natural form of 5-methyltetrahydrofolate by the layers, so that the human can solve the problem of insufficient folic acid intake while ingesting food. This paper reviewed the folic acid enrichment rule in eggs and its absorption and metabolism in the intestine, liver, ovary and kidney, and the metabolic regulation mechanism of folate in layers was explained. The purpose of this paper was to provide theoretical basis for further research of folic acid in layers.

Cite this article

SUN Dandan , ZHANG Junmin , ZHAO Qingyu , QIN Yuchang . Advances in Absorption and Metabolism of Folate and Its Mechanism in Layers[J]. Chinese Journal of Animal Nutrition, 2020 , 32(6) : 2467 -2475 . DOI: 10.3969/j.issn.1006-267x.2020.06.004

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