Effects of Pediococcus acidilactici on Growth Performance, Fecal Microbiota, Serum Biochemical and Immune Indexes of Growing Pigs

  • LIU Hui ,
  • JI Haifeng ,
  • WANG Sixin ,
  • ZHANG Dongyan ,
  • WANG Jing ,
  • ZHANG Wei ,
  • WANG Yamin
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  • Institute of Animal Husbandry and Veterinary Medicine, Beijing Academy of Agriculture and Forestry Sciences, Beijing 100097, China

Received date: 2019-12-23

  Online published: 2020-06-16

Abstract

This experiment was conducted to evaluate the effects of Pediococcus acidilactici on growth performance, fecal microbiota, serum biochemical and immune indexes of growing pigs. A total of 140 "Landrace×Yorkshire" crossbred growing pigs with an average body weight of (23.21±0.84) kg were divided into 2 groups: control group and experimental group. Each group had 5 replicates with 14 pigs per replicate. Pigs in the control group were fed a basal diet, and those in the experimental group were fed the basal diet supplemented with 2.70×109 CFU/kg Pediococcus acidilactici freeze-drying preparation. The adjustment period was 5 d, and the experiment period was 34 d. The results showed that compared with the control group: 1) the average daily gain (ADG) of growing pigs was increased by 5.64% (P<0.05), and the feed/gain (F/G) was decreased by 4.62% (P<0.05) in the experimental group; 2) the number of fecal lactic acid bacteria of growing pigs was significantly increased (P<0.05), and the numbers of Escherichia coli and Staphylococcus aureus were significantly decreased (P<0.05) in the experimental group; 3) Pediococcus acidilactici increased the fecal microbiota species richness, the proportions of Firmicutes, Prevotella, Megasphaera and Lactobacillus were also increased in the experimental group; 4) the contents of serum total protein (TP), globulin (GLB), immunoglobulin G (IgG) and immunoglobulin A (IgA) were increased by 13.45% (P<0.05), 14.91% (P<0.05), 20.91% (P<0.05) and 44.00% (P<0.05), and the contents of serum urea nitrogen (UN) and haptoglobin (HP) were decreased by 19.46% (P<0.05) and 38.71% (P<0.05) in the experimental group, respectively. The results indicate that dietary supplemented with 2.70×109 CFU/kg Pediococcus acidilactici can improve the intestinal microbiota composition, enhance the immune function and improve the growth performance of growing pigs.

Cite this article

LIU Hui , JI Haifeng , WANG Sixin , ZHANG Dongyan , WANG Jing , ZHANG Wei , WANG Yamin . Effects of Pediococcus acidilactici on Growth Performance, Fecal Microbiota, Serum Biochemical and Immune Indexes of Growing Pigs[J]. Chinese Journal of Animal Nutrition, 2020 , 32(6) : 2558 -2566 . DOI: 10.3969/j.issn.1006-267x.2020.06.015

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