The purpose of this experiment was to study the effects of diets with different supplemental levels of compound acidifier on growth performance, nutrient apparent digestibility, slaughter performance and meat quality of commercial meat rabbits. On basis of weight and gender, three hundred healthy 35-day-old IRA weaned rabbits (male and female account for 1/2, respectively) were randomly divided into 5 groups with 60 replicates in each group and 1 rabbit in each replicate. The 5 groups included a blank control group (fed a basal diet), an antibiotic control group (fed the basal diet+emramycin 20 g/t+chloroterracycline 300 g/t) and 3 trial groups. The rabbits in trial groups 1, 2 and 3 were fed experimental diets which supplemented with 0.1%, 0.2% and 0.3% compound acidifier (the ratio of potassium dicarboxylate to phosphoric acid was 3:2) based on the basal diet, respectively. There were a pre-test of 5 days and a formal period of 26 days. The results showed as follows: 1) there were no significant differences in the final body weight, average daily gain and feed/gain among trial groups 1, 2, 3 and antibiotic control group (P>0.05), but those three growth indices of the trial group 1 were significantly higher than those of the blank control group (P<0.05). 2) There were no significant differences in the apparent digestibility of dry matter, crude protein, ash, neutral detergent fiber and acid detergent fiber between trial group 1 and antibiotic control group (P>0.05), but that of the trial group 1 was extremely significantly higher than that of the blank control group (P<0.01). The apparent digestibility of crude protein and ash of the trial groups 1 and 2 was extremely significantly higher than that of the trial group 3 (P<0.05). 3)The carcass weight and semi-eviscerated ratio of the trial group 1 were significantly higher than those of the blank control group and the trial group 3 (P<0.05), but had no significant differences compared with the antibiotic control group and the trial group 2 (P>0.05). 4) There were no significant differences in the meat quality indexes (physical properties and chemical indexes) of rabbits among all groups (P>0.05). On the basis of all the measured indexes, it is concluded that the compound acidifier which composed of potassium dicarboxylate to phosphoric acid with the ratio of 3:2 on rabbit-related indicators can be applied to the commercial meat rabbit diet to replace antibiotic, and the optimum additive amount is 0.1%.