The purpose of this experiment was to study the effects of different processing Chinese gall instead of zinc oxide on growth performance, nutrient apparent digestibility, cecal microbial flora and diarrhea rate of piglets. A total of 195 "Duroc×Landrace×Yorkshire" piglets with an average body weight of (9.97±0.04) kg were selected and randomly divided into 5 groups. Each group contained 3 replicates and each replicate contained 13 piglets with male and female evenly distributed. The piglets in control group were fed a basal diet supplemented with 2 092 mg/kg zinc oxide (that was equivalent to 1 600 mg/kg zinc), the piglets in Chinese gall powder (GP) group were fed the basal diet supplemented with 852 mg/kg GP, the piglets in Chinese gall powder hydrolyzed gallotannin extract (HGT) group were fed the basal diet supplemented with 649 mg/kg HGT, the piglets in coated-GP (C-GP) group were fed the basal diet supplemented with 1 970 mg/kg C-GP, and the piglets in coated-HGT (C-HGT) group were fed the basal diet supplemented with 1 974 mg/kg C-HGT. The supplemental levels of hydrolyzed gallotannin in the 4 trial groups were 600 mg/kg, separately. The pre-test period was 7 days, and the formal test period was 25 days. The results showed as follows:1) the final average body weight, average daily feed intake, average daily gain and feed/gain ratio had no significant difference among the 5 groups (P>0.05). 2) Compared with the control group, the diarrhea rate of the 4 trial groups had an upward trend (P=0.076). 3) The crude protein apparent digestibility of the HGT group and C-HGT group was significantly higher than that of the control group, GP group and C-GP group (P<0.01). The ether extract apparent digestibility of the HGT group and C-HGT group had no significant difference compared with the control group (P>0.05), but that of the GP group and C-GP group was significantly higher than that of the control group, HGT group and C-HGT group (P<0.01). 4) Compared with the control group, the abundance of Faecalibacterium in cecum of 4 trial groups were all improved to some degree. The present study suggests that different processing Chinese gall instead of zinc oxide in the diet does not affect the growth performance of piglets, but the diarrhea rate is upward trend. Compared with the zinc oxide, the apparent digestibility of crude protein can be improved by Chinese gall treated by extraction process (HGT and C-HGT), while the apparent digestibility of ether extract can be reduced by Chinese gall untreated by extraction process (GP and C-GP). The abundance of Faecalibacterium in cecum of piglets is increased after dietary zinc oxide replaced by different processing Chinese gall.