Effects of Compound Lactobacillus on Growth Performance, Serum Biochemical Indexes, Intestinal Development and Digestive Enzyme Activities of Early-Weaned Yak Calves

NIE Zhaolong; PAN Hao; LIU Shujie; WANG Lei; SUN Lu; FENG Yuzhe; ZHANG Xiaowei; CUI Zhanhong

doi:10.3969/j.issn.1006-267x.2020.08.035

2020 , Vol. 32 >Issue 8: 3760 - 3770

DOI: https://doi.org/10.3969/j.issn.1006-267x.2020.08.035

Effects of Compound Lactobacillus on Growth Performance, Serum Biochemical Indexes, Intestinal Development and Digestive Enzyme Activities of Early-Weaned Yak Calves

NIE Zhaolong ,
PAN Hao ,
LIU Shujie ,
WANG Lei ,
SUN Lu ,
FENG Yuzhe ,
ZHANG Xiaowei ,
CUI Zhanhong

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1. Academy of Animal and Veterinary Sciences, Qinghai University, Xining 810016, China;
2. Yak Engineering Technology Research Center in Qinghai Province, Xining 810016, China;
3. Key Laboratory of Grazing Animal Nutrition and Feed Science of Qinghai Province, Xining 810016, China

Received date: 2020-03-02

Online published: 2020-08-13

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Abstract

This experiment was conducted to study the effects of compound Lactobacillus on growth performance, serum biochemical indexes, intestinal development and digestive enzyme activities of early-weaned yak calves. Ten male yak calves (twenty-eight days weaned) were randomly divided into 2 groups (5 replicates in each group and 5 calves in each replicate), yak calves were feed the basal diet (group CT) and basal diet supplemented with compound Lactobacillus (group LBS), respectively. Each yak calf was offered 1.7×10¹⁰ CFU/d compound Lactobacillus (Pedicoccus acidilacticii:Pediococcuspentosaceus:Lactobacillus plantarum=1:1:1). The experiment lasted for 56 days. The results showed as follows:1) during the whole experimental period (days 1 to 56), the average daily gain, total dry matter intake and alfalfa intake of group LBS was higher than those of group CT (P>0.05), and the starter intake was significantly higher than that of group CT (P<0.01). 2) On day 56, the serum glutamic-pyruvic transaminase activity of group LBS was significantly lower than that of group CT (P<0.01); on day 28, the serum alkaline phosphatase activity of group LBS was significantly higher than that of group CT (P<0.05), and the serum glucose content of group LBS was significantly higher than that of group CT (P<0.01). 3) The muscularis thickness in duodenum of group LBS was significantly higher than that of group CT (P<0.05), and the villus height/crypt depth in duodenum was significantly higher than that of group CT (P<0.01); the mucosal thickness in jejunum of group LBS was significantly higher than that of group CT (P<0.05), and the muscularis thickness and villus height/crypt depth in jejunum were significantly higher than those of group CT (P<0.01); the crypt depth in ileum of group LBS was significantly lower than that of group CT (P<0.05), and the villus height/crypt depth in ileum was significantly higher than that of group CT (P<0.01). 4) The ileum mucosa tumor necrosis factor-α content of group LBS was significantly higher than that of group CT (P<0.01), the duodenum and jejunum mucosa interferon-γ content was significantly lower than that of group CT (P<0.05), and the contents of interleukin-10 and interleukin-4 in jejunum mucosa were significantly higher than those of group CT (P<0.05). 5) The jejunum and ileum trypsase activity of group LBS was significantly higher than that of group CT (P<0.05), and the ileum lipase activity was significantly higher than that of group CT (P<0.01). In conclusion, feeding compound Lactobacillus can improve the growth performance of early-weaned yak calves, enhance the ability of nutrients absorption and utilization, and has positive regulatory effects on intestinal development and immunity.

Key words： yak calves; compound Lactobacillus; early weaned; growth performance; intestinal tissue; mucosal immunity

Cite this article

NIE Zhaolong , PAN Hao , LIU Shujie , WANG Lei , SUN Lu , FENG Yuzhe , ZHANG Xiaowei , CUI Zhanhong . Effects of Compound Lactobacillus on Growth Performance, Serum Biochemical Indexes, Intestinal Development and Digestive Enzyme Activities of Early-Weaned Yak Calves[J]. Chinese Journal of Animal Nutrition, 2020 , 32(8) : 3760 -3770 . DOI: 10.3969/j.issn.1006-267x.2020.08.035

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