[1] SÁNCHEZ-ÁLVAREZ M,STRIPPOLI R,DONADELLI M,et al.Sestrins as a therapeutic bridge between ROS and autophagy in cancer[J].Cancers,2019,11(10):E1415.
[2] WANG T,WANG Q W,SONG R L,et al.Autophagy plays a cytoprotective role during cadmium-induced oxidative damage in primary neuronal cultures[J].Biological Trace Element Research,2015,168(2):481-489.
[3] TANG Y L,LI J J,LI F N,et al.Autophagy protects intestinal epithelial cells against deoxynivalenol toxicity by alleviating oxidative stress via IKK signaling pathway[J].Free Radical Biology and Medicine,2015,89:944-951.
[4] CHEN Y Q,KLIONSKY D.The regulation of autophagy-unanswered questions[J].Journal of Cell Science,2011,124(2):161-170.
[5] HOSOKAWA N,HARA T,KAIZUKA T,et al.Nutrient-dependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy[J].Molecular Biology of the Cell,2009,20(7):1981-1991.
[6] RAVANAN P,SRIKUMAR I F,TALWAR P.Autophagy:the spotlight for cellular stress responses[J].Life Science,2017,188:53-67.
[7] LEVINE B,KROEMER G.Biological functions of autophagy genes:a disease perspective[J].Cell,2019,176(1/2):11-42.
[8] GATICA D,LAHIRI V,KLIONSKY D.Cargo recognition and degradation by selective autophagy[J].Nature Cell Biology,2018,20(3):233-242.
[9] DRAKE L E,SPRINGER M Z,POOLE L P,et al.Expanding perspectives on the significance of mitophagy in cancer[J].Seminars in Cancer Biology,2017,47:110-124.
[10] WYANT G,ABU-REMAILEH M,FRENKEL E,et al.NUFIP1 is a ribosome receptor for starvation-induced ribophagy[J].Science,2018,360(6390):751-758.
[11] CHAUHAN S,KUMAR S,JAIN A,et al.TRIMs and galectins globally cooperate and TRIM16 and galectin-3 co-direct autophagy in endomembrane damage homeostasis[J].Developmental Cell,2016,39(1):13-27.
[12] YOSHIDA Y,YASUDA S,FUJITA T,et al.Ubiquitination of exposed glycoproteins by SCFFBXO27 directs damaged lysosomes for autophagy[J].Proceedings of the National Academy of Sciences of the United States of America,2017,114(32):8574-8579.
[13] CIPOLLA C M,LODHI I J.Peroxisomal dysfunction in age-related diseases[J].Trends in Endocrinology and Metabolism,2017,28(4):297-308.
[14] ZECHNER R,MADEO F,KRATKY D.Cytosolic lipolysis and lipophagy:two sides of the same coin[J].Nature Reviews Molecular Cell Biology,2017,18(11):671-684.
[15] FRANCO L H,NAIR V R,SCHARN C R,et al.The ubiquitin ligase SMURF1 functions in selective autophagy of
Mycobacterium tuberculosis and anti-tuberculous host defense[J].Cell Host and Microbe,2017,21(1):59-72.
[16] MITCHELL G,ISBERG R R.Innate immunity to intracellular pathogens:balancing microbial elimination and inflammation[J].Cell Host and Microbe,2017,22(2):166-175.
[17] LIU G,SABATINI D M.mTOR at the nexus of nutrition,growth,ageing and disease[J].Nature Reviews Molecular Cell Biology,2020,doi:10.1038/s41580-019-0199-y.
[18] ZACHARI M,GANLEY I G.The mammalian ULK1 complex and autophagy initiation[J].Essays in Biochemistry,2017,61(6):585-596.
[19] LAND S C,TEE A R.Hypoxia-inducible factor 1α is regulated by the mammalian target of rapamycin (mTOR) via an mTOR signaling motif[J].The Journal of Biological Chemistry,2007,282(28):20534-20543.
[20] GÖRLACH A,BONELLO S.The cross-talk between NF-κB and HIF-1:further evidence for a significant liaison[J].Biochemical Journal,2008,412(3):e17-e19.
[21] HUANG J,LAM G Y,BRUMELL J H.Autophagy signaling through reactive oxygen species[J].Antioxidants & Redox Signaling,2011,14(11):2215-2231.
[22] SU Z D,BURCHFIELD J G,YANG P Y,et al.Global redox proteome and phosphoproteome analysis reveals redox switch in Akt[J].Nature Communication,2019,10:5486.
[23] SCHERZ-SHOUVAL R,SHVETS E,FASS E,et al.Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4[J].EMBO Journal,2007,26(7):1749-1760.
[24] LIU B,CHENG Y,ZHANG B,et al.
Polygonatum cyrtonema lectin induces apoptosis and autophagy in human melanoma A375 cells through a mitochondria-mediated ROS-p38-p53 pathway[J].Cancer Letters,2009,275(1):54-60.
[25] WANG S H,SHIH Y,KUO T C,et al.Cadmium toxicity toward autophagy through ROS-activated GSK-3β in mesangial cells[J].Toxicological Sciences,2009,108(1):124-131.
[26] CHO S H,LEE C H,AHN Y,et al.Redox regulation of PTEN and protein tyrosine phosphatases in H
2O
2-mediated cell signaling[J].FEBS Letters,2004,560(1/2/3):7-13.
[27] COOKE M S,EVANS M D,DIZDAROGLU M,et al.Oxidative DNA damage:mechanisms,mutation,and disease[J].The FASEB Journal,2003,17(10):1195-1214.
[28] NARENDRA D,TANAKA A,SUEN D F,et al.Parkin is recruited selectively to impaired mitochondria and promotes their autophagy[J].The Journal of Cell Biology,2008,183(5):795-803.
[29] WU H,CHEN Q.Hypoxia activation of mitophagy and its role in disease pathogenesis[J].Antioxidants and Redox Signaling,2015,22(12):1032-1046.
[30] ROOS W P,KAINA B.DNA damage-induced cell death:from specific DNA lesions to the DNA damage response and apoptosis[J].Cancer Letters,2013,332(2):237-248.
[31] DOTIWALA F,EAPEN V V,HARRISON J C,et al.DNA damage checkpoint triggers autophagy to regulate the initiation of anaphase[J].Proceedings of the National Academy of Sciences of the United States of America,2013,110(1):E41-E49.
[32] RODRÍGUEZ-VARGAS J,RUIZ-MAGAÑA M,RUIZ-RUIZ C,et al.ROS-induced DNA damage and PARP-1 are required for optimal induction of starvation-induced autophagy[J].Cell Research,2012,22(7):1181-1198.
[33] ALEXANDER A,CAI S L,KIM J,et al.ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROS[J].Proceedings of the National Academy of Sciences of the United States of America,2010,107(9):4153-4158.
[34] CHEN T W,LUO W,WU G J,et al.A novel MyD88 inhibitor LM9 prevents atherosclerosis by regulating inflammatory responses and oxidative stress in macrophages[J].Toxicology and Applied Pharmacology,2019,370:44-55.
[35] DERETIC V,LEVINE B.Autophagy balances inflammation in innate immunity[J].Autophagy,2018,14(2):243-251.
[36] SAITOH T,FUJITA N,JANG M H,et al.Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1β production[J].Nature,2008,456(7219):264-268.
[37] SUMPTER R,Jr,SIRASANAGANDLA S,FERNÁNDEZ Á F,et al.Fanconi anemia proteins function in mitophagy and immunity[J].Cell,2016,165(4):867-881.
[38] KIMURA T,JAIN A,CHOI S W,et al.TRIM-mediated precision autophagy targets cytoplasmic regulators of innate immunity[J].The Journal of Cell Biology,2015,210(6):973-989.
[39] LIU T,TANG Q,LIU K P,et al.TRIM11 suppresses AIM2 inflammasome by degrading AIM2 via p62-dependent selective autophagy[J].Cell Reports,2016,16(7):1988-2002.
[40] MATSUZAWA-ISHIMOTO Y,HWANG S,CADWELL K.Autophagy and inflammation[J].Annual Review of Immunology,2018,36:73-101.
[41] STRANKS A J,HANSEN A L,PANSE I,et al.Autophagy controls acquisition of aging features in macrophages[J].Journal of Innate Immunity,2015,7(4):375-391.
[42] LEE J P W,FOOTE A,FAN H P,et al.Loss of autophagy enhances MIF/macrophage migration inhibitory factor release by macrophages[J].Autophagy,2016,12(6):907-916.
[43] TAL M C,SASAI M,LEE H K,et al.Absence of autophagy results in reactive oxygen species-dependent amplification of RLR signaling[J].Proceedings of the National Academy of Sciences of the United States of America,2009,106(8):2770-2775.
[44] RAVINDRAN R,KHAN N,NAKAYA H I,et al.Vaccine activation of the nutrient sensor GCN2 in dendritic cells enhances antigen presentation[J].Science,2014,343(6168):313-317.
[45] KHAN N,VIDYARTHI A,PAHARI S,et al.Signaling through NOD-2 and TLR-4 bolsters the T cell priming capability of dendritic cells by inducing autophagy[J].Scientific Reports,2016,6:19084.
[46] CASTILLO E F,DEKONENKO A,ARKO-MENSAH J,et al.Autophagy protects against active tuberculosis by suppressing bacterial burden and inflammation[J].Proceedings of the National Academy of Sciences of the United States of America,2012,109(46):E3168-E3176.
[47] MITROULIS I,KOURTZELIS I,KAMBAS K,et al.Regulation of the autophagic machinery in human neutrophils[J].European Journal of Immunology,2010,40(5):1461-1472.
[48] REMIJSEN Q,BERGHE T V,WIRAWAN E,et al.Neutrophil extracellular trap cell death requires both autophagy and superoxide generation[J].Cell Research,2011,21(2):290-304.
[49] PEI B,ZHAO M,MILLER B C,et al.Invariant NKT cells require autophagy to coordinate proliferation and survival signals during differentiation[J].The Journal of Immunology,2015,194(12):5872-5884.
[50] O'SULLIVAN T E,JOHNSON L R,KANG H H,et al.BNIP3-and BNIP3L-mediated mitophagy promotes the generation of natural killer cell memory[J].Immunity,2015,43(2):331-342.
[51] O'SULLIVAN T E,GEARY C D,WEIZMAN O E,et al.Atg5 is essential for the development and survival of innate lymphocytes[J].Cell Reports,2016,15(9):1910-1919.
[52] MATSUZAWA Y,OSHIMA S,TAKAHARA M,et al.TNFAIP3 promotes survival of CD4 T cells by restricting MTOR and promoting autophagy[J].Autophagy,2015,11(7):1052-1062.
[53] JIA W,HE M X,MCLEOD I X,et al.Autophagy regulates T lymphocyte proliferation through selective degradation of the cell-cycle inhibitor CDKN1B/p27Kip1[J].Autophagy,2015,11(12):2335-2345.
[54] CHEN M,HONG M J,SUN H H,et al.Essential role for autophagy in the maintenance of immunological memory against influenza infection[J].Nature Medicine,2014,20(5):503-510.
[55] PAPADOPOULOS C,KIRCHNER P,BUG M,et al.VCP/p97 cooperates with YOD1,UBXD1 and PLAA to drive clearance of ruptured lysosomes by autophagy[J].EMBO Journal,2017,36(2):135-150.
[56] YOSHII S R,KISHI C,ISHIHARA N,et al.Parkin mediates proteasome-dependent protein degradation and rupture of the outer mitochondrial membrane[J].The Journal of Biological Chemistry,2011,286(22):19630-19640.
[57] WEI Y J,CHIANG W C,SUMPTER R,et al.Prohibitin 2 is an inner mitochondrial membrane mitophagy receptor[J].Cell,2017,168(1/2):224-238.e10.
[58] ZHOU H L,WERTZ I,O'ROURKE K,et al.Bcl10 activates the NF-κB pathway through ubiquitination of NEMO[J].Nature,2003,427(6970):167-171.
[59] GU X,OROZCO J M,SAXTON R A,et al.SAMTOR is an S-adenosylmethionine sensor for the mTORC1 pathway[J].Science,2017,358(6364):813-818.
[60] TAN S H,SHUI G,ZHOU J,et al.Induction of autophagy by palmitic acid via protein kinase C-mediated signaling pathway independent of mTOR (mammalian target of rapamycin)[J].The Journal of Biological Chemistry,2012,287(18):14364-14376.
[61] KOGA H,KAUSHIK S,CUERVO A M.Altered lipid content inhibits autophagic vesicular fusion[J].The FASEB Journal,2010,24(8):3052-3065.
[62] CHU Q,YU X,JIA R Y,et al.Flavonoids from
Apios americana Medikus leaves protect RAW264.7 cells against inflammation via inhibition of MAPKs,Akt-mTOR pathways,and Nfr2 activation[J].Oxidative Medicine and Cellular Longevity,2019,2019:1563024.
[63] ASHRAFIZADEH M,AHMADI Z,FARKHONDEH T,et al.Autophagy as a molecular target of quercetin underlying its protective effects in human diseases[J].Archives of Physiology and Biochemistry,2019,28:1-9.
[64] ZHANG E X,YIN S T,ZHAO S,et al.Protective effects of glycycoumarin on liver diseases[J].Phytotherapy Research,2019:1-7,doi:10.1002/ptr.6598.
[65] XUAN H Z,OU A Q,HAO S Y,et al.Galangin protects against symptoms of dextran sodium sulfate-induced acute colitis by activating autophagy and modulating the gut microbiota[J].Nutrients,2020,12(2):347.
[66] BRIDGEMAN B B,WANG P,YE B P,et al.Inhibition of mTOR by apigenin in UVB-irradiated keratinocytes:a new implication of skin cancer prevention[J].Cellular Signalling,2016,28(5):460-468.
[67] LIU L Y,WU Y X,HUANG X L.Orientin protects myocardial cells against hypoxia-reoxygenation injury through induction of autophagy[J].European Journal of Pharmacology,2016,776:90-98.
[68] JOHANSON I,MONSEN V T,PETTERSEN K,et al.The marine n-3 PUFA DHA evokes cytoprotection against oxidative stress and protein misfolding by inducing autophagy and NFE2L2 in human retinal pigment epithelial cells[J].Autophagy,2015,11(9):1636-1651.
[69] WU Y P,WANG B K,XU H,et al.Probiotic
Bacillus attenuates oxidative stress-induced intestinal injury via p38-mediated autophagy[J].Frontiers in Microbiology,2019,10:2185.
[70] YANG J H,CHEN Q,TIAN S Y,et al.The role of 1,25-dyhydroxyvitamin D
3 in mouse liver ischemia reperfusion injury:regulation of autophagy through activation of MEK/ERK signaling and PTEN/PI3K/Akt/mTORC1 signaling[J].American Journal of Translational Research,2015,7(12):2630-2645.
[71] SEBORI R,KUNO A,HOSODA R,et al.Resveratrol decreases oxidative stress by restoring mitophagy and improves the pathophysiology of dystrophin-deficient
mdx mice[J].Oxidative Medicine and Cellular Longevity,2018,2018:9179270.
[72] KIM S H,KIM H.Astaxanthin modulation of signaling pathways that regulate autophagy[J].Marine Drugs,2019,17(10):546.
