Effects of Sodium Butyrate and Yucca on Growth Performance and Serum Antioxidant Indices of Sucking Calves Challenged with Escherichia coli K99

  • LIU Wenhui ,
  • Alatengzhula ,
  • MA Lu ,
  • REN Lijuan ,
  • GAO Shengtao ,
  • BU Dengpan
Expand
  • 1. Institute of Animal Science, State Key Laboratory of Animal Nutrition, Chinese Academy of Agricultural Sciences, Beijing 100193, China;
    2. Chinese Academy of Agricultural Sciences and World Agroforestry Center Joint Lab on Agroforestry and Sustainable Animal Husbandry, Beijing 100193, China

Received date: 2020-03-21

  Online published: 2020-09-17

Abstract

This experiment was conducted to evaluate effects of sodium butyrate and Yucca on growth performance and serum antioxidant indices of sucking calves challenged with Escherichia coli K99. A total of 40 healthy Holstein calves with similar body weight of (40±5) kg were randomly allocated to 4 groups with 10 calves per group. The control group (C group) was fed a basic diet, the sodium butyrate group (SB group) was fed the basic diet+30 g/d sodium butyrate, the Yucca group (Y group) was fed the basic diet+9 g/d Yucca, and the sodium butyrate+Yucca group (SB+Y group) was fed the basic diet+30 g/d sodium butyrate+9 g/d Yucca. The calves were challenged with Escherichia coli K99 at 7 days of age, and the experiment ended at 14 days of age. The results showed as follows:1) during 1 to 7 days of age, compared with the SB group, the average daily feed intake of calves of SB+Y group was significantly decreased (P<0.05). 2) At 11 days of age, the serum catalase (CAT) activity of calves of SB group was significantly higher than that of C group (P<0.05); at 14 days of age, the serum CAT activity of calves of SB group and Y group was significantly higher than that of C group and SB+Y group (P<0.05). At 11 days of age, compared with C group, the serum glutathione peroxidase (GSH-Px) activity of calves of Y group had a tendency to increase (P=0.088), and the serum GSH-Px activity of calves of SB+Y group was significantly increased (P<0.05). At 7 days of age, compared with C group, the serum malondialdehyde (MDA) content of calves of Y group had a tendency to decrease (P=0.050); at 7 days of age, compared with C group, the serum MDA content of calves of SB+Y group had a tendency to decrease (P=0.089). In conclusion, when sucking calves are under stress condition challenged with Escherichia coli K99, the separately supplementation of sodium butyrate and Yucca can improve the antioxidant capacity of calves, but it has no effect on the growth performance of calves. The combined supplementation of sodium butyrate and Yucca can improve the antioxidant capacity of calves, but reduce the average daily feed intake of calves.

Cite this article

LIU Wenhui , Alatengzhula , MA Lu , REN Lijuan , GAO Shengtao , BU Dengpan . Effects of Sodium Butyrate and Yucca on Growth Performance and Serum Antioxidant Indices of Sucking Calves Challenged with Escherichia coli K99[J]. Chinese Journal of Animal Nutrition, 2020 , 32(9) : 4177 -4184 . DOI: 10.3969/j.issn.1006-267x.2020.09.027

References

[1] BALDWIN R L,MCLEOD K R,KLOTZ J L,et al.Rumen development,intestinal growth and hepatic metabolism in the pre-and postweaning ruminant[J].Journal of Dairy Science,2004,87(Suppl.1):E55-E65.
[2] SHAMS Z,TAHAMTAN Y,POURBAKHSH A,et al.Detection of enterotoxigenic K99(F5) and F41 from fecal sample of calves by molecular and serological methods[J].Comparative Clinical Pathology,2012,21(4):475-478.  
[3] KOLENDA R,BURDUKIEWICZ M,SCHIERACK P.A systematic review and meta-analysis of the epidemiology of pathogenic Escherichia coli of calves and the role of calves as reservoirs for human pathogenic E. coli[J].Frontiers in Cellular and Infection Microbiology,2015,5:23.
[4] OK M,GULER L,TURGUT K,et al.The studies on the aetiology of diarrhoea in neonatal calves and determination of virulence gene markers of Escherichia coli strains by multiplex PCR[J].Zoonoses and Public Health,2009,56(2):94-101.  
[5] 左丽君,姜宁,张爱忠.丁酸钠对畜禽机体营养及免疫调控作用的研究进展[J].中国畜牧杂志,2019,55(4):25-28.
[6] WU Y N,ZHOU Y M,LU C H,et al.Influence of butyrate loaded clinoptilolite dietary supplementation on growth performance,development of intestine and antioxidant capacity in broiler chickens[J].PLoS One,2016,11(4):e0154410.
[7] SCHEPPACH W,BARTRAM P,RICHTER A,et al.Effect of short-chain fatty acids on the human colonic mucosa in vitro[J].Journal of Parenteral and Enteral Nutrition,1992,16(1):43-48.  
[8] GUILLOTEAU P,ZABIELSKI R,DAVID J C,et al.Sodium-butyrate as a growth promoter in milk replacer formula for young calves[J].Journal of Dairy Science,2009,92(3):1038-1049.  
[9] GUILLOTEAU P,ZABIELSKI R,BLUM J W.Gastrointestinal tract and digestion in the young ruminant:ontogenesis,adaptations,consequences and manipulations[J].Journal of Physiology and Pharmacology,2009,60(Suppl 3):37-46.
[10] PENNER G B,ASCHENBACH J R,GÄBEL G,et al.Epithelial capacity for apical uptake of short chain fatty acids is a key determinant for intraruminal pH and the susceptibility to subacute ruminal acidosis in sheep[J].The Journal of Nutrition,2009,139(9):1714-1720.  
[11] 赵会利,高艳霞,李建国,等.丁酸钠对断奶犊牛生长、血液生化指标及胃肠道发育的影响[J].畜牧兽医学报,2013,44(10):1600-1608.
[12] BEIRANVAND H,GHORBANI G R,KHORVASH M,et al.Interactions of alfalfa hay and sodium propionate on dairy calf performance and rumen development[J].Journal of Dairy Science,2014,97(4):2270-2280.  
[13] GÁLFI P,BOKORI J.Feeding trial in pigs with a diet containing sodium n-butyrate[J].Acta Veterinaria Hungarica,1990,38(1/2):3-17.
[14] HILL T M,ALDRICH J M,SCHLOTTERBECK R L,et al.Effects of changing the fat and fatty acid composition of milk replacers fed to neonatal calves[J].The Professional Animal Scientist,2007,23(2):135-143.  
[15] XIONG H T,GUO B X,GAN Z S,et al.Butyrate upregulates endogenous host defense peptides to enhance disease resistance in piglets via histone deacetylase inhibition[J].Scientific Reports,2016,6:27070.
[16] CHEEKE P R.Actual and potential applications of Yucca schidigera and Quillaja saponaria saponins in human and animal nutrition[C]//OLESZEK W,MARSTON A.Saponins in food, feedstuffs and medicinal plants.Netherlands:Springer,2000,77:241-254.
[17] 龚红,邹胜龙.丝兰提取物的研究与应用[J].饲料研究,2015(1):14-17,39.
[18] PERRON N R,BRUMAGHIM J L.A review of the antioxidant mechanisms of polyphenol compounds related to iron binding[J].Cell Biochemistry and Biophysics,2009,53(2):75-100.  
[19] 田丽新,史彬林,李倜宇,等.丝兰提取物对奶牛免疫和抗氧化功能的影响[J].饲料研究,2016(3):33-35,57.
[20] DE SOUSA O A,COOKE R F,BRANDÃO A P,et al.Productive and physiological responses of feeder cattle supplemented with Yucca schidigera extract during feedlot receiving[J].Journal of Animal Science,2019,97(1):208-219.  
[21] ABDEL-RAHEEM S M,FARGHALY M M,HASSAN E H.Effect of dietary supplementation with Yucca schidigera powder on nutrient digestibility,rumen fermentation,ruminal enzyme activities and growth performance of buffalo calves[J].Biological Rhythm Research,2019,doi:10.1080/09291016.2019.1691832.
[22] NRC.Nutrient requirements of dairy cattle[S].7th ed.Washington,D.C.:National Academy Press,2001.
[23] PAL B,PACHAURI S.Effect of oral rehydration in neonatal calves treated for diarrhoea induced with Escherichia coli (O101:K99) infection[J].The Indian Journal of Veterinary Research,2008,17(1):19-26.
[24] BESSER T E,RICHARDS B L,RICE D H,et al.Escherichia coli O157:H7 infection of calves:infectious dose and direct contact transmission[J].Epidemiology & Infection,2001,127(3):555-560.  
[25] AOAC.Official methods of analysis of the association of official analytical chemists[S].17th ed.Washington D.C.:AOAC,2000.
[26] VAN SOEST P J,ROBERTSON J B,LEWIS B A.Symposium:carbohydrate methodology, metabolism, and nutritional implications in dairy cattle[J].Journal of Dairy Science,1991,74(10):3583-3597.  
[27] GLOVER A D,PUSCHNER B,ROSSOW H A,et al.A double-blind block randomized clinical trial on the effect of zinc as a treatment for diarrhea in neonatal Holstein calves under natural challenge conditions[J].Preventive Veterinary Medicine,2013,112(3/4):338-347.
[28] SLUSARCZYK K,STRZETELSKI J,FURGA?-DIER? UK I.The effect of sodium butyrate on calf growth and serum level of β-hydroxybutyric acid[J].Journal of Animal and Feed Sciences,2010,19(3):348-357.  
[29] FRIETEN D,GERBERT C,KOCH C,et al.Ad libitum milk replacer feeding,but not butyrate supplementation,affects growth performance as well as metabolic and endocrine traits in Holstein calves[J].Journal of Dairy Science,2017,100(8):6648-6661.  
[30] GORKA P,KOWALSKI Z M,PIETRZAK P,et al.Effect of sodium butyrate supplementation in milk replacer and starter diet on rumen development in calves[J].Journal of Physiology and Pharmacology,2009,60(Suppl.3):47-53.
[31] GORKA P,KOWALSKI Z M,PIETRZAK P,et al.Effect of method of delivery of sodium butyrate on rumen development in newborn calves[J].Journal of Dairy Science,2011,94(11):5578-5588.  
[32] KOCH C,GERBERT C,FRIETEN D,et al.Effects of ad libitum milk replacer feeding and butyrate supplementation on the epithelial growth and development of the gastrointestinal tract in Holstein calves[J].Journal of Dairy Science,2019,102(9):8513-8526..  
[33] O'LOUGHLIN E V,SCOTT R B,GALL D G.Pathophysiology of infectious diarrhea:changes in intestinal structure and function[J].Journal of Pediatric Gastroenterology and Nutrition,1991,12(1):5-20.  
[34] BI Y L,YANG C T,DIAO Q Y,et al.Effects of dietary supplementation with two alternatives to antibiotics on intestinal microbiota of preweaned calves challenged with Escherichia coli K99[J].Scientific Reports,2017,7(1):5439.
[35] GUILLOTEAU P,MARTIN L,EECKHAUT V,et al.From the gut to the peripheral tissues:the multiple effects of butyrate[J].Nutrition Research Reviews,2010,23(2):366-384.  
[36] PATRA A K,STIVERSON J,YU Z.Effects of Quillaja and Yucca saponins on communities and select populations of rumen bacteria and archaea,and fermentation in vitro[J].Journal of Applied Microbiology,2012,113(6):1329-1340.  
[37] CADENAS E,DAVIES K J A.Mitochondrial free radical generation,oxidative stress,and aging[J].Free Radical Biology and Medicine,2000,29(3/4):222-230.
[38] MOORE J W,BABIDGE W,MILLARD S,et al.Effect of sulphide on short chain acyl-CoA metabolism in rat colonocytes[J].Gut,1997,41(1):77-81.  
[39] SAUER J,RICHTER K K,POOL-ZOBEL B L.Physiological concentrations of butyrate favorably modulate genes of oxidative and metabolic stress in primary human colon cells[J].The Journal of Nutritional Biochemistry,2007,18(11):736-745.  
[40] MRUK D D,SILVESTRINI B,MO M Y,et al.Antioxidant superoxide dismutase-a review:its function,regulation in the testis,and role in male fertility[J].Contraception,2002,65(4):305-311.  
[41] BOWLER C,SLOOTEN L,VANDENBRANDEN S,et al.Manganese superoxide dismutase can reduce cellular damage mediated by oxygen radicals in transgenic plants[J].The Embo Journal,1991,10(7):1723-1732.  
[42] CIGERCI I H,FIDAN A F,KONUK M,et al.The protective potential of Yucca schidigera (Sarsaponin 30) against nitrite-induced oxidative stress in rats[J].Journal of Natural Medicines,2009,63(3):311-317.  
[43] ZHU L H,ZHAO K L,CHEN X L,et al.Impact of weaning and an antioxidant blend on intestinal barrier function and antioxidant status in pigs[J].Journal of Animal Science,2012,90(8):2581-2589.  
[44] SEBAI H,JABRI M A,SOULI A,et al.Antidiarrheal and antioxidant activities of chamomile (Matricaria recutita L.) decoction extract in rats[J].Journal of Ethnopharmacology,2014,152(2):327-333.  
Outlines

/