Nutritional Regulation on Immunity Based on Pig Disease Model

  • YAN Hui ,
  • MAO Xiangbing ,
  • YU Bing ,
  • CHEN Daiwen
Expand
  • Animal Nutrition Institute, Sichuan Agricultural University, Chengdu 611130, China

Received date: 2020-08-17

  Online published: 2020-10-22

Abstract

Modern medicine and nutrition studies have found that nutrition has a regulatory effect on the immune response. This review will combine the experience of our team in disease-resistant nutrition research. First, summarize the immune mechanism of pigs, including immune recognition, activation and regulation of immune response. Then, the common disease model in swine nutrition, including chemical challenge models and pathogen challenge models, is briefly introduced. Finally, based on the disease models, the research progress of nutrition and immunity will be summarized, aiming to provide the practice guidance of disease-resistant nutrition and reference for the further nutrition and immunity research.

Cite this article

YAN Hui , MAO Xiangbing , YU Bing , CHEN Daiwen . Nutritional Regulation on Immunity Based on Pig Disease Model[J]. Chinese Journal of Animal Nutrition, 2020 , 32(10) : 4471 -4479 . DOI: 10.3969/j.issn.1006-267x.2020.10.001

References

[1] MURPHY M,WEAVER C.Janeway's immunobiology[M].9th ed.New York,NY:Garland Science,2016.
[2] XIAO Y,YAN H L,DIAO H,et al.Early gut microbiota intervention suppresses DSS-induced inflammatory responses by deactivating TLR/NLR signalling in pigs[J].Scientific Reports,2017,7:3224.
[3] 单虎.兽医传染病学[M].北京:中国农业大学出版社,2017.
[4] 陈谊,郑明.人猪共患疾病与感染[M].北京:中国农业出版社,2017.
[5] MA Y L,WANG C L,XUE M,et al.The coronavirus transmissible gastroenteritis virus evades the type Ⅰ interferon response through IRE1α-mediated manipulation of the microRNA miR-30a-5p/SOCS1/3 axis[J].Journal of Virology,2018,92(22):e00728-18.
[6] WU A M,YU B,ZHANG K Y,et al.Transmissible gastroenteritis virus targets Paneth cells to inhibit the self-renewal and differentiation of Lgr5 intestinal stem cells via Notch signaling[J].Cell Death & Disease,2020,11:40.
[7] 孙东波,武瑞,孔凡志.猪流行性腹泻病毒研究进展[M].北京:科学出版社,2018.
[8] 古长松.饲粮添加异亮氨酸对轮状病毒攻毒仔猪生长性能和免疫功能的影响[D].硕士学位论文.成都:四川农业大学,2018.
[9] MAO X B,GU C S,REN M,et al.L-isoleucine administration alleviates rotavirus infection and immune response in the weaned piglet model[J].Frontiers in Immunology,2018,9:1654.
[10] ZHAO Y,RAN Z M,JIANG Q,et al.Vitamin D alleviates rotavirus infection through a microRNA-155-5p mediated regulation of the TBK1/IRF3 signaling pathway in vivo and in vitro[J].International Journal of Molecular Sciences,2019,20(14):3562.
[11] 彭燮.低蛋白日粮添加合成氨基酸或完整蛋白对仔猪生长性能、氮代谢和免疫功能的影响[D].硕士学位论文.雅安:四川农业大学,2016.
[12] 赖翔.饲粮添加苏氨酸对PRV诱导的免疫应激仔猪生长性能和免疫功能的影响[D].硕士学位论文.雅安:四川农业大学,2012.
[13] 杨平.饲粮添加L-精氨酸或N-氨甲酰谷氨酸对感染PRRSV妊娠母猪繁殖性能及免疫功能的影响[D].硕士学位论文.雅安:四川农业大学,2011.
[14] 王岚.猪传染性胃肠炎病毒(TGEV)感染IPEC-J2细胞的炎症反应及亮氨酸的调控作用[D].硕士学位论文.成都:四川农业大学,2019.
[15] 刘忠臣.不同来源脂肪对仔猪的营养效应及对E. coli攻毒的保护作用研究[D].博士学位论文.雅安:四川农业大学,2011.
[16] 赵叶.不同猪种抗病毒相关模式识别受体基因表达差异及维生素D的抗病毒作用与机制[D].博士学位论文.雅安:四川农业大学,2013.
[17] ZHAO Y,YU B,MAO X B,et al.Dietary vitamin D supplementation attenuates immune responses of pigs challenged with rotavirus potentially through the retinoic acid-inducible gene Ⅰ signalling pathway[J].British Journal of Nutrition,2014,112(3):381-389.  
[18] 陈宏.生物素对断奶仔猪生产性能及免疫功能影响的研究[D].博士学位论文.雅安:四川农业大学,2008.
[19] 高庆.饲粮添加叶酸对断奶仔猪生产性能和免疫功能的影响研究[D].博士学位论文.雅安:四川农业大学,2011.
[20] 龚伟,王哲,张乃生,等.硒对免疫功能影响的研究进展[J].动物医学进展,1998,19(4):16-18.
[21] 黎文彬.酵母硒对脂多糖(LPS)诱导的免疫应激早期断奶仔猪的影响[D].硕士学位论文.雅安:四川农业大学,2009.
[22] 陈浩.饲粮添加果胶寡糖对轮状病毒攻毒仔猪生产性能、免疫功能和肠道健康的影响[D].硕士学位论文.雅安:四川农业大学,2016.
[23] WAN J,ZHANG J,WU G Z,et al.Amelioration of enterotoxigenic Escherichia coli-induced intestinal barrier disruption by low-molecular-weight chitosan in weaned pigs is related to suppressed intestinal inflammation and apoptosis[J].International Journal of Molecular Sciences,2019,20(14):3485.
[24] ZHANG J,WAN J,WU G Z,et al.Low-molecular-weight chitosan relieves enterotoxigenic Escherichia coli-induced growth retardation in weaned pigs[J].International Immunopharmacology,2020,78:105798.
[25] 秦林林.银耳孢子多糖对母猪繁殖性能及后代生产性能和免疫功能的影响[D].硕士学位论文.成都:四川农业大学,2018.
[26] 王纯刚,张克英,丁雪梅.丁酸钠对轮状病毒攻毒和未攻毒断奶仔猪生长性能和肠道发育的影响[J].动物营养学报,2009,21(5):711-718.
[27] YAN H,AJUWON K M.Butyrate modifies intestinal barrier function in IPEC-J2 cells through a selective upregulation of tight junction proteins and activation of the Akt signaling pathway[J].PLoS One,2017,12(6):e0179586.
[28] 王俊文.饲粮添加白藜芦醇对接种蓝耳病弱毒苗育肥猪生产性能和免疫功能及肉品质的影响[D].硕士学位论文.雅安:四川农业大学,2012.
[29] 贾淋雁.饲粮添加铜和植物精油对猪流行性腹泻病毒攻毒仔猪生长性能和免疫功能的影响[D].硕士学位论文.成都:四川农业大学,2019.
[30] SMITH B N,DILGER R N.Immunomodulatory potential of dietary soybean-derived isoflavones and saponins in pigs[J].Journal of Animal Science,2018,96(4):1288-1304.  
[31] WATTANASATCHA A,RENGPIPAT S,WANICHWECHARUNGRUANG S.Thymol nanospheres as an effective anti-bacterial agent[J].International Journal of Pharmaceutics,2012,434(1/2):360-365.
[32] 徐琴.饲粮中添加活性酵母对断奶仔猪生长性能和ETEC攻毒后肠道及免疫功能的影响[D].硕士学位论文.成都:四川农业大学,2017.
[33] 汤俊.饲粮添加鼠李糖乳酸杆菌GG对轮状病毒攻毒仔猪免疫功能和肠道健康的影响[D].硕士学位论文.雅安:四川农业大学,2015.
Outlines

/