Research Progress of Nutritional Regulation for Meat Quality of Pigs

  • ZHANG Xin ,
  • WANG Yubo ,
  • HUANG Zhiqing ,
  • SU Yong ,
  • LI Fengna ,
  • YIN Jingdong
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  • 1. State Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China;
    2. Animal Nutrition Institute, Sichuan Agricultural University, Chengdu 611130, China;
    3. College of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China;
    4. Institute of Subtropical Agriculture, Chinese Academy of Sciences, Changsha 410125, China

Received date: 2020-08-03

  Online published: 2020-10-22

Abstract

To yield qualified pork is one of the ultimate aims of the pig industry. China is the biggest country of pork production and consumption; however, meat quality is far below the consumer expectation. In this review, we discussed the progress on mechanism of meat quality formation in terms of two key biological characteristics of muscle of myofiber development and intramuscular fat deposition. And based on this, we reviewed the research progress of improving meat quality through changed the supply of amino acids/fatty acids in recent five years, and supply of functional additives and microbial preparation. We proposed to further deepen the basic research on meat quality formation and establish more feasible domestic pork quality evaluation system, promoting the precise practice of nutritional regulation of meat quality to meet pig industry sustainable development and consumer’s demands.

Cite this article

ZHANG Xin , WANG Yubo , HUANG Zhiqing , SU Yong , LI Fengna , YIN Jingdong . Research Progress of Nutritional Regulation for Meat Quality of Pigs[J]. Chinese Journal of Animal Nutrition, 2020 , 32(10) : 4555 -4564 . DOI: 10.3969/j.issn.1006-267x.2020.10.009

References

[1] 尹靖东,李德发.猪肉质形成的分子机制与营养调控[J].动物营养学报,2014,26(10):2979-2985.
[2] CHOE J H,CHOI Y M,LEE S H,et al.The relation between glycogen,lactate content and muscle fiber type composition,and their influence on postmortem glycolytic rate and pork quality[J].Meat Science,2008,80(2):355-362.  
[3] XU D D,WANG Y B,JIAO N,et al.The coordination of dietary valine and isoleucine on water holding capacity,pH value and protein solubility of fresh meat in finishing pigs[J].Meat Science,2020,163:108074.
[4] JATURASITHA S,CHAIWANG N,KAYAN A,et al.Nutritional strategies to improve the lipid composition of meat,with emphasis on Thailand and Asia[J].Meat Science,2016,120:157-166.
[5] 农秋雲,刘嘉琪,单体中.猪肉中脂肪酸组成的品种差异及脂肪酸沉积的调控机制[J].动物营养学报,2019,31(6):2507-2514.
[6] ZHANG Y F,ZHANG J J,GONG H F,et al.Genetic correlation of fatty acid composition with growth,carcass,fat deposition and meat quality traits based on GWAS data in six pig populations[J].Meat Science,2019,150:47-55.
[7] DU M,HUANG Y,DAS A K,et al.Meat science and muscle biology symposium:manipulating mesenchymal progenitor cell differentiation to optimize performance and carcass value of beef cattle[J].Journal of Animal Science,2013,91(3):1419-1427.  
[8] MURPHY M,KARDON G.Origin of vertebrate limb muscle:the role of progenitor and myoblast populations[J].Current Topics in Developmental Biology,2011,96:1-32.
[9] HORN R V,CROW M T.Fast myosin heavy chain expression during the early and late embryonic stages of chicken skeletal muscle development[J].Developmental Biology,1989,134(2):279-288.  
[10] MILLAY D P,O'ROURKE J R,SUTHERLAND L B,et al.Myomaker is a membrane activator of myoblast fusion and muscle formation[J].Nature,2013,499(7458):301-305.  
[11] BI P P,RAMIREZ-MARTINEZ A,LI H,et al.Control of muscle formation by the fusogenic micropeptide myomixer[J].Science,2017,356(6335):323-327.  
[12] WANG T,XU Y Q,YUAN Y X,et al.Succinate induces skeletal muscle fiber remodeling via SUNCR1 signaling[J].EMBO Reports,2019,20(9):e47892.
[13] XU M,CHEN X L,CHEN D W,et al.MicroRNA-499-5p regulates skeletal myofiber specification via NFATc1/MEF2C pathway and Thrap1/MEF2C axis[J].Life Sciences,2018,215:236-245.
[14] DU J J,ZHANG P W,ZHAO X,et al.MicroRNA-351-5p mediates skeletal myogenesis by directly targeting lactamase-β and is regulated by lnc-mg[J].The FASEB Journal,2019,33(2):1911-1926.  
[15] ZHANG S R,CHEN X L,HUANG Z Q,et al.Leucine promotes porcine myofibre type transformation from fast-twitch to slow-twitch through the protein kinase B (Akt)/forkhead box 1 signalling pathway and microRNA-27a[J].British Journal of Nutrition,2019,121(1):1-8.  
[16] WEN W X,CHEN X L,HUANG Z Q,et al.Resveratrol regulates muscle fiber type conversion via miR-22-3p and AMPK/SIRT1/PGC-1α pathway[J].The Journal of Nutritional Biochemistry,2020,77:108297.
[17] 杨媛媛,李敬,赵青余,等.猪肌肉糖原酵解潜力的影响因素及其营养调控研究进展[J].中国畜牧杂志,2019,55(11):8-15.
[18] BARNES B R,GLUND S,LONG Y C,et al.5'-AMP-activated protein kinase regulates skeletal muscle glycogen content and ergogenics[J].The FASEB Journal,2005,19(7):773-779.
[19] SCHEFFLER T L,SCHEFFLER J M,KASTEN S C,et al.High glycolytic potential does not predict low ultimate pH in pork[J].Meat Science,2013,95(1):85-91.  
[20] MILAN D,JEON J T,LOOFT C,et al.A mutation in PRKAG3 associated with excess glycogen content in pig skeletal muscle[J].Science,2000,288(5469):1248-1251.  
[21] MA J W,YANG J,ZHOU L S,et al.A splice mutation in the PHKG1 gene causes high glycogen content and low meat quality in pig skeletal muscle[J].PLoS Genetics,2014,10(10):e1004710.
[22] UEZUMI A,FUKADA S I,YAMAMOTO N,et al.Mesenchymal progenitors distinct from satellite cells contribute to ectopic fat cell formation in skeletal muscle[J].Nature Cell Biology,2010,12(2):143-152.  
[23] LI X,FU X,YANG G,et al.Review:enhancing intramuscular fat development via targeting fibro-adipogenic progenitor cells in meat animals[J].Animal,2020,14(2):312-321.  
[24] SUN Y M,QIN J,LIU S G,et al.PDGFRα regulated by miR-34a and FoxO1 promotes adipogenesis in porcine intramuscular preadipocytes through ERK signaling pathway[J].International Journal of Molecular Sciences,2017,18(11):2424.
[25] CHEN F F,WANG Y Q,TANG G R,et al.Differences between porcine longissimus thoracis and semitendinosus intramuscular fat content and the regulation of their preadipocytes during adipogenic differentiation[J].Meat Science,2019,147:116-126.
[26] GONZÁLEZ-PRENDES R,QUINTANILLA R,MÁRMOL-SÁNCHEZ E,et al.Comparing the mRNA expression profile and the genetic determinism of intramuscular fat traits in the porcine Gluteus medius and longissimus dorsi muscles[J].BMC Genomics,2019,20:170.
[27] XU K,JI M,HUANG X,et al.Differential regulatory roles of microRNAs in porcine intramuscular and subcutaneous adipocytes[J].Journal of Agricultural and Food Chemistry,2020,68(13):3954-3962.  
[28] MIAO Z G,WANG S,WANG Y M,et al.Comparison of microRNAs in the intramuscular adipose tissue from Jinhua and Landrace pigs[J].Journal of Cellular Biochemistry,2019,120(1):192-200.  
[29] JIANG Q,SUN B F,LIU Q,et al.MTCH2 promotes adipogenesis in intramuscular preadipocytes via an m6A-YTHDF1-dependent mechanism[J].The FASEB Journal,2019,33(2):2971-2981.  
[30] SUN W J,HE T,QIN C F,et al.A potential regulatory network underlying distinct fate commitment of myogenic and adipogenic cells in skeletal muscle[J].Scientific Reports,2017,7:44133.
[31] ZHANG X,WANG L Q,QIU K,et al.Dynamic membrane proteome of adipogenic and myogenic precursors in skeletal muscle highlights EPHA2 may promote myogenic differentiation through ERK signaling[J].The FASEB Journal,2019,33(4):5495-5509.  
[32] QIU K,ZHANG X,WANG L Q,et al.Protein expression landscape defines the differentiation potential specificity of adipogenic and myogenic precursors in the skeletal muscle[J].Journal of Proteome Research,2018,17(11):3853-3865.  
[33] GUO B,ZHANG W G,TUME R K,et al.Disorder of endoplasmic reticulum calcium channel components is associated with the increased apoptotic potential in pale,soft,exudative pork[J].Meat Science,2016,115:34-40.
[34] WANG Y Y,LIU R,TIAN X N,et al.Comparison of activity,expression,and S-nitrosylation of calcium transfer proteins between pale,soft,and exudative and red,firm,and non-exudative pork during post-mortem aging[J].Journal of Agricultural and Food Chemistry,2019,67(11):3242-3248.  
[35] HOU X H,LIU Q F,MENG Q S,et al.TMT-based quantitative proteomic analysis of porcine muscle associated with postmortem meat quality[J].Food Chemistry,2020,328:127133.
[36] JIN C L,YE J L,YANG J Z,et al.mTORC1 mediates lysine-induced satellite cell activation to promote skeletal muscle growth[J].Cells,2019,8(12):1549.
[37] JIN C L,ZHANG Z M,SONG Z W,et al.mTORC1-mediated satellite cell differentiation is required for lysine-induced skeletal muscle growth[J].Journal of Agricultural and Food Chemistry,2020,68(17):4884-4892.  
[38] SONG Z W,JIN C L,YE M,et al.Lysine inhibits apoptosis in satellite cells to govern skeletal muscle growth via the JAK2-STAT3 pathway[J].Food & Function,2020,11(5):3941-3951.  
[39] JIN C L,ZHANG Z M,YE J L,et al.Lysine-induced swine satellite cell migration is mediated by the FAK pathway[J].Food & Function,2019,10(2):583-591.  
[40] SUÁREZ-BELLOCH J,GUADA J A,LATORRE M A.Effects of sex and dietary lysine on performances and serum and meat traits in finisher pigs[J].Animal,2015,9(10):1731-1739.  
[41] ZOU T D,MAO X B,YU B,et al.Effects of dietary energy density and apparent ileal digestible lysine:digestible energy ratio on growth performance,meat quality,and peroxisome proliferator-activated receptor γ (PPARγ) gene expression of muscle and adipose tissues in Landrace×Rongchang crossbred pigs[J].Livestock Science,2014,167:219-226.
[42] MADEIRA M S,COSTA P,ALFAIA C M,et al.The increased intramuscular fat promoted by dietary lysine restriction in lean but not in fatty pig genotypes improves pork sensory attributes[J].Journal of Animal Science,2013,91(7):3177-3187.  
[43] WU L,ZHANG H W,NA L,et al.Methionine restriction at the post-weanling period promotes muscle fiber transition in piglets and improves intramuscular fat content in growing-finishing pigs[J].Amino Acids,2019,51(10/11/12):1657-1666.
[44] CHEN X L,XIANG L,JIA G,et al.Leucine regulates slow-twitch muscle fibers expression and mitochondrial function by Sirt1/AMPK signaling in porcine skeletal muscle satellite cells[J].Animal Science Journal,2019,90(2):255-263.  
[45] 王宇波,许豆豆,何鑫,等.低蛋白饲粮缬氨酸水平对肥育猪生长性能、胴体性状和肉品质的影响[J].畜牧兽医学报,2019,50(9):1832-1840.
[46] LUO Y H,ZHANG X,ZHU Z P,et al.Surplus dietary isoleucine intake enhanced monounsaturated fatty acid synthesis and fat accumulation in skeletal muscle of finishing pigs[J].Journal of Animal Science and Biotechnology,2018,9:88.
[47] 李燕舞,石英,庞纪彩.L-精氨酸对肥育猪生长性能、营养物质消化率、气体排放和肉质的影响[J].中国饲料,2019(18):76-78.
[48] GUO Q,KONG X F,HU C J,et al.Fatty acid content,flavor compounds,and sensory quality of pork loin as affected by dietary supplementation with L-arginine and glutamic acid[J].Journal of Food Science,2019,84(12):3445-3453.  
[49] CHEN X L,LUO X M,CHEN D W,et al.Arginine promotes porcine type Ⅰ muscle fibres formation through improvement of mitochondrial biogenesis[J].British Journal of Nutrition,2020,123(5):499-507.  
[50] CHEN X L,GUO Y F,JIA G,et al.Arginine promotes skeletal muscle fiber type transformation from fast-twitch to slow-twitch via Sirt1/AMPK pathway[J].The Journal of Nutritional Biochemistry,2018,61:155-162.
[51] MADEIRA M S,ALFAIA C M,COSTA P,et al.Effect of betaine and arginine in lysine-deficient diets on growth,carcass traits,and pork quality[J].Journal of Animal Science,2015,93(10):4721-4733.  
[52] 邓波,门小明,吴杰,等.亚麻籽对生长育肥猪生长性能、胴体性状、肉质和脂肪酸组成的影响[J].动物营养学报,2019,31(9):4024-4032.
[53] 陈静,孙娜,刘显军,等.紫苏油对育肥猪血清脂质指标、胴体性能及肉品质的影响[J].动物营养学报,2019,31(11):5329-5337.
[54] CORDERO G,ISABEL B,MENOYO D,et al.Dietary CLA alters intramuscular fat and fatty acid composition of pig skeletal muscle and subcutaneous adipose tissue[J].Meat Science,2010,85(2):235-239.  
[55] BARNES K M,WINSLOW N R,SHELTON A G,et al.Effect of dietary conjugated linoleic acid on marbling and intramuscular adipocytes in pork[J].Journal of Animal Science,2012,90(4):1142-1149.  
[56] ZHOU X,LI D F,YIN J D,et al.CLA differently regulates adipogenesis in stromal vascular cells from porcine subcutaneous adipose and skeletal muscle[J].Journal of Lipid Research,2007,48(8):1701-1709.  
[57] CHANG S,CHEN X L,HUANG Z Q,et al.Dietary sodium butyrate supplementation promotes oxidative fiber formation in mice[J].Animal Biotechnology,2018,29(3):212-215.  
[58] ZHANG Y,YU B,YU J,et al.Butyrate promotes slow-twitch myofiber formation and mitochondrial biogenesis in finishing pigs via inducing specific microRNAs and PGC-1α expression[J].Journal of Animal Science,2019,97(8):3180-3192.  
[59] DUAN Y H,LI F N,LI L L,et al.n-6:n-3 PUFA ratio is involved in regulating lipid metabolism and inflammation in pigs[J].British Journal of Nutrition,2014,111(3):445-451.  
[60] LI F N,DUAN Y H,LI Y H,et al,2015.Effects of dietary n-6:n-3 PUFA ratio on fatty acid composition,free amino acid profile and gene expression of transporters in finishing pigs[J].British Journal of Nutrition,2015,113(5):739-748.  
[61] LU Y F,ZOU T D,WANG Z R,et al.Dietary guanidinoacetic acid improves the growth performance and skeletal muscle development of finishing pigs through changing myogenic gene expression and myofibre characteristics[J].Journal of Animal Physiology and Animal Nutrition,2020,doi:10.1111/jpn.13351.
[62] LI J L,ZHANG L,FU Y N,et al.Creatine monohydrate and guanidinoacetic acid supplementation affects the growth performance,meat quality,and creatine metabolism of finishing pigs[J].Journal of Agricultural and Food Chemistry,2018,66(38):9952-9959.  
[63] ZHU Z P,GU C S,HU S D,et al.Dietary guanidinoacetic acid supplementation improved carcass characteristics,meat quality and muscle fibre traits in growing-finishing gilts[J].Journal of Animal Physiology and Animal Nutrition,2020,doi:10.1111/jpn.13410.
[64] XING Y T,WU X,XIE C Y,et al.Meat quality and fatty acid profiles of Chinese Ningxiang pigs following supplementation with N-carbamylglutamate[J].Animals,2020,10(1):88.
[65] YE C C,ZENG X Z,ZHU J L,et al.Dietary N-carbamylglutamate supplementation in a reduced protein diet affects carcass traits and the profile of muscle amino acids and fatty acids in finishing pigs[J].Journal of Agricultural and Food Chemistry,2017,65(28):5751-5758.  
[66] XU X J,CHEN X L,CHEN D W,et al.Effects of dietary apple polyphenol supplementation on carcass traits,meat quality,muscle amino acid and fatty acid composition in finishing pigs[J].Food & Function,2019,10(11):7426-7434.  
[67] CHEN X L,JIA G,LIU G M,et al.Effects of apple polyphenols on myofiber-type transformation in longissimus dorsi muscle of finishing pigs[J].Animal Biotechnology,2020:1-8,doi:10.1080/10495398.2020.1735405..
[68] ZHANG C,LUO J Q,YU B,et al.Dietary resveratrol supplementation improves meat quality of finishing pigs through changing muscle fiber characteristics and antioxidative status[J].Meat Science,2015,102:15-21.
[69] MENG Q W,SUN S S,BAI Y S,et al.Effects of dietary resveratrol supplementation in sows on antioxidative status,myofiber characteristic and meat quality of offspring[J].Meat Science,2020,167:108176.
[70] YANG K L,WANG L N,ZHOU G,et al.Phytol promotes the formation of slow-twitch muscle fibers through PGC-1α/miRNA but not mitochondria oxidation[J].Journal of Agricultural and Food Chemistry,2017,65(29):5916-5925.  
[71] ZHOU G,WANG L N,XU Y Q,et al.Diversity effect of capsaicin on different types of skeletal muscle[J].Molecular and Cellular Biochemistry,2018,443(1/2):11-23.
[72] ALBUQUERQUE A,NEVES J A,REDONDEIRO M,et al.Long term betaine supplementation regulates genes involved in lipid and cholesterol metabolism of two muscles from an obese pig breed[J].Meat Science,2017,124:25-33.
[73] 宋博,郑昌炳,仲银召,等.低蛋白质饲粮中添加构树全株发酵饲料对育肥猪生长性能、胴体性状和肉品质的影响[J/OL].动物营养学报,2020.(2020-07-11).https://kns.cnki.net/KCMS/detail/11.5461.S.20200710.1650.004.html.
[74] YAN H L,DIAO H,XIAO Y,et al.Gut microbiota can transfer fiber characteristics and lipid metabolic profiles of skeletal muscle from pigs to germ-free mice[J].Scientific Reports,2016,6:31786.
[75] XIAO Y P,KONG F L,XIANG Y,et al.Comparative biogeography of the gut microbiome between Jinhua and Landrace pigs[J].Scientific Reports,2018,8:5985.
[76] LI Y H,LIU Y Y,LI F N,et al.Effects of dietary ramie powder at various levels on carcass traits and meat quality in finishing pigs[J].Meat Science,2018,143:52-59.
[77] LIU Y Y,LI Y H,PENG Y L,et al.Dietary mulberry leaf powder affects growth performance,carcass traits and meat quality in finishing pigs[J].Journal of Animal Physiology and Animal Nutrition,2019,103(6):1934-1945.  
[78] FANG S M,XIONG X W,SU Y,et al.16S rRNA gene-based association study identified microbial taxa associated with pork intramuscular fat content in feces and cecum lumen[J].BMC Microbiology,2017,17:162.
[79] JOYSOWAL M,SAIKIA B N,DOWARAH R,et al.Effect of probiotic Pediococcus acidilactici FT28 on growth performance,nutrient digestibility,health status,meat quality,and intestinal morphology in growing pigs[J].Veterinary World,2018,11(12):1669-1676.
[80] YU K F,ZHANG Y N,CHEN H Z,et al.Hepatic metabolomic and transcriptomic responses induced by cecal infusion of sodium propionate in a fistula pig model[J].Journal of Agricultural and Food Chemistry,2019,67(47):13073-13081.  
[81] MENG Q W,YAN L,AO X,et al.Influence of probiotics in different energy and nutrient density diets on growth performance,nutrient digestibility,meat quality,and blood characteristics in growing-finishing pigs[J].Journal of Animal Science,2010,88(10):3320-3226.  
[82] ?LI?EWSKA K,CHLEBICZ A.Synbiotics impact on dominant faecal microbiota and short-chain fatty acids production in sows[J].FEMS Microbiology Letters,2019,366(13):157.
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