[1] PARK H,KIM H J,JEONG M S,et al.Monitoring of pesticide residues in animal feeds from the republic of Korea[J].Journal of Animal Science,2016,94(Suppl.5):282.
[2] 吴雨珊,孙丹丹,李军国,等.奶牛饲料中多种农药残留调查分析[J].食品安全质量检测学报,2019,10(11):3273-3279.
[3] NAG S K,RAIKWAR M K.Persistent organochlorine pesticide residues in animal feed[J].Environmental Monitoring and Assessment,2011,174(1/2/3/4):327-335.
[4] 贺顺喜,周师军.应重视食品残留农药的监测[J].解放军健康,2002(2):17.
[5] 吴建生,赵文标.安全合理使用农药防治园林植物病虫害[J].中国园艺文摘,2015(6):223-224.
[6] SHARMA A,KUMAR V,SHAHZAD B,et al.Worldwide pesticide usage and its impacts on ecosystem[J].SN Applied Sciences,2019,1(11):1446.
[7] PARIONA A.Top pesticide using countries[J/OL].Worldatlas,2018[2018-04-25].https://www.worldatlas.com/articles/top-pesticide-consuming-countries-of-the-world.html.
[8] 中国农业工业协会.2016年销售额超3亿美元农药产品汇总及重点品种情况介绍[J].农药市场信息,2017(27):31-33,36-37.
[9] EFSA.National summary reports on pesticide residue analysis performed in 2018[R].[s.l.]:EFSA Supporting Publications,2020.
[10] Anon.Pesticide residue monitoring program fiscal year 2016 pesticide report[J/OL].U.S.Food and Drug Administration,2018[2018-10-13].https://www.fda.gov/Food/FoodborneIllnessContaminants/Pesticides/default.htm.
[11] MARTÍNEZ M A,ARES I,RODRÍGUEZ J L,et al.Neurotransmitter changes in rat brain regions following glyphosate exposure[J].Environmental Research,2018,161:212-219.
[12] DE SOUZA J S,LAUREANO-MELO R,HERAI R H,et al.Maternal glyphosate-based herbicide exposure alters antioxidant-related genes in the brain and serum metabolites of male rat offspring[J].Neuro Toxicology,2019,74:121-131.
[13] REN X,LI R N,LIU J Z,et al.Effects of glyphosate on the ovarian function of pregnant mice,the secretion of hormones and the sex ratio of their fetuses[J].Environmental Pollution,2018,243:833-841.
[14] DAI P Y,HU P,TANG J,et al.Effect of glyphosate on reproductive organs in male rat[J].Acta Histochemica,2016,118(5):519-526.

[15] DURAND P,BLONDET A,MARTIN G,et al.Effects of a mixture of low doses of atrazine and benzo[a]pyrene on the rat seminiferous epithelium either during or after the establishment of the blood-testis barrier in the rat seminiferous tubule culture model[J].Toxicology in Vitro,2020,62:104699.
[16] 张婧.辛硫磷对大鼠和仔猪的不良影响及维生素E的缓解作用[D].博士学位论文.哈尔滨:东北农业大学,2019.
[17] 孙岳丞.辛硫磷对大鼠和仔猪肠屏障影响及维生素E的保护作用[D].硕士学位论文.哈尔滨:东北农业大学,2018.
[18] 宋文涛.辛硫磷对大鼠和仔猪糖代谢的影响以及维生素E的保护作用[D].硕士学位论文.哈尔滨:东北农业大学,2017.
[19] 付慧洋.草甘膦对雌性断奶仔猪肝脏和生殖系统的影[D].硕士学位论文.哈尔滨:东北农业大学,2020.
[20] 邱胜男.草甘膦对仔猪肠道屏障功能的影响及分子机制研究[D].硕士学位论文.哈尔滨:东北农业大学,2020.
[21] GIGANTE P,BERNI M,BUSSOLATI S,et al.Glyphosate affects swine ovarian and adipose stromal cell functions[J].Animal Reproduction Science,2018,195,185-196.
[22] HENDERSON A J,FINGER B J,SCOTT A W,et al.Acute
in vitro exposure to environmentally relevant atrazine levels perturbs bovine preimplantation embryo metabolism and cell number[J].Reproductive Toxicology,2019,87:87-96.
[23] 赵华山.核受体应答在阿特拉津致鹌鹑大脑线粒体损伤中的作用[D].硕士学位论文.哈尔滨:东北农业大学,2017.
[24] XIA J,QIN L,DU Z H,et al.Performance of a novel atrazine-induced cerebellar toxicity in quail (
Coturnix C.coturnix):activating PXR/CAR pathway responses and disrupting cytochrome P450 homeostasis[J].Chemosphere,2017,171:259-264.
[25] 张丛.核受体AHR/CAR/Nrf2级联信号通路在阿特拉津致鹌鹑肾毒性中的作用[D].硕士学位论文.哈尔滨:东北农业大学,2017.
[26] 李雪楠.IRE1α/TRAF2/NF-κB信号通路在阿特拉津致鹌鹑心脏炎症性损伤中的作用[D].硕士学位论文.哈尔滨:东北农业大学,2017.
[27] QIN L,DU Z H,ZHU S Y,et al.Atrazine triggers developmental abnormality of ovary and oviduct in quails (
Coturnix coturnix coturnix) via disruption of hypothalamo-pituitary-ovarian axis[J].Environmental Pollution,2015,207:299-307.
[28] 李薇.阿特拉津致鹌鹑卵巢颗粒细胞毒性机制的研究[D].硕士学位论文.哈尔滨:东北农业大学,2019.
[29] MÁRQUEZ-LÁZARO J P,MORA L,MÉNDEZ-CUADRO D,et al.
In vitro oxidation promoted by chlorpyrifos residues on myosin and chicken breast proteins[J].Food Chemistry,2020,326:126922.
[30] ALOIZOU A M,SIOKAS V,VOGIATZI C,et al.Pesticides,cognitive functions and dementia:a review[J].Toxicology Letters,2020,326:31-51.
[31] 边连全.农药残留对饲料的污染及其对畜产品安全的危害[J].饲料工业,2005,26(9):1-5.
[32] YOON M,KEDDERIS G L,YAN G Z,et al.Use of
in vitro data in developing a physiologically based pharmacokinetic model:carbaryl as a case study[J].Toxicology,2015,332:52-66.
[33] KHEDR T,HAMMAD A A,ELMARSAFY A M,et al.Degradation of some organophosphorus pesticides in aqueous solution by gamma irradiation[J].Journal of Hazardous Materials,2019,373:23-28.
[34] JAESCHKE H.Reactive oxygen and mechanisms of inflammatory liver injury[J].Journal of Gastroenterology and Hepatology,2000,15(7):718-724.

[35] 钟敏.Nrf2-Keap1抗氧化系统研究进展[J].中国公共卫生,2006,22(3):360-362.
[36] MCMAHON M,THOMAS N,ITOH K,et al.Redox-regulated turnover of Nrf2 is determined by at least two separate protein domains,the redox-sensitive Neh2 degron and the redox-insensitive Neh6 degron[J].Journal of Biological Chemistry,2004,279(30):31556-31567.

[37] KOBAYASHI A,KANG M I,OKAWA H,et al.Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate proteasomal degradation of Nrf2[J].Molecular and Cellular Biology,2004,24(16):7130-7139.

[38] 张大生.醌氧化还原1与血根碱肝细胞毒相关性及机理的研究[D].博士学位论文.长沙:湖南农业大学,2015.
[39] LIU H,YANG J,HUANG S W,et al.Mulberry crude extracts induce Nrf2 activation and expression of detoxifying enzymes in rat liver:implication for its protection against NP-induced toxic effects[J].Journal of Functional Foods,2017,32:367-374.
[40] ZIPPER L M,MULCAHY R T.Erk activation is required for Nrf2 nuclear localization during pyrrolidine dithiocarbamate induction of glutamate cysteine ligase modulatory gene expression in HepG2 cells[J].Toxicological Sciences,2003,73(1):124-134.

[41] DE AGUIAR L M,FIGUEIRA F H,GOTTSCHALK M S,et al.Glyphosate-based herbicide exposure causes antioxidant defence responses in the fruit fly
Drosophila melanogaster[J].Comparative Biochemistry and Physiology Part C:Toxicology & Pharmacology,2016,185-186:94-101.
[42] HAN E S,MULLER F L,PÉREZ V I,et al.The
in vivo gene expression signature of oxidative stress[J].Physiological Genomics,2008,34(1):112-126.

[43] QIU S N,FU H Y,ZHOU R Y,et al.Toxic effects of glyphosate on intestinal morphology,antioxidant capacity and barrier function in weaned piglets[J].Ecotoxicology and Environmental Safety,2020,187:109846.
[44] 相丽润.Nrf2信号通路在阿特拉津致鹌鹑肝脏氧化应激中的作用[D].硕士学位论文.哈尔滨:东北农业大学,2016.
[45] ROSS J,PLUMMER S M,RODE A,et al.Human constitutive androstane receptor (CAR) and pregnane X receptor (PXR) support the hypertrophic but not the hyperplastic response to the murine nongenotoxic hepatocarcinogens phenobarbital and chlordane
in vivo[J].Toxicological Sciences,2010,116(2):452-466.

[46] WADA T,GAO J,XIE W.PXR and CAR in energy metabolism[J].Trends in Endocrinology & Metabolism,2009,20(6):273-279.

[47] FU H Y,QIU S N,YAO X X,et al.Toxicity of glyphosate in feed for weanling piglets and the mechanism of glyphosate detoxification by the liver nuclear receptor CAR/PXR pathway[J].Journal of Hazardous Materials,2020,387:121707.
[48] URANO F,WANG X Z,BERTOLOTTI A,et al.Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1[J].Science,2000,287(5453):664-666.

[49] HAN Y T,SONG L,AN Q S,et al.Removal of six pesticide residues in cowpea with alkaline electrolysed water[J].Journal of the Science of Food and Agriculture,2017,97(8):2333-2338.

[50] 刘红玉,陈振德,汪东风,等.高铁酸钾对菠菜中3种有机磷农药残留降解的影响[J].生态毒理学报,2009,4(2):282-288.
[51] JIANG Z,LI J J,JIANG D,et al.Removal of atrazine by biochar-supported zero-valent iron catalyzed persulfate oxidation:reactivity,radical production and transformation pathway[J].Environmental Research,2020,184:109260.
[52] MAQBOOL Z,HUSSAIN S,IMRAN M,et al.Perspectives of using fungi as bioresource for bioremediation of pesticides in the environment:a critical review[J].Environmental Science and Pollution Research,2016,23(17):16904-16925.

[53] JIANG B,ZHANG N N,XING Y,et al.Microbial degradation of organophosphorus pesticides:novel degraders,kinetics,functional genes,and genotoxicity assessment[J].Environmental Science and Pollution Research,2019,26(21):21668-21681.

[54] MENG D,JIANG W,LI J,et al.An alkaline phosphatase from
Bacillus amyloliquefaciens YP6 of new application in biodegradation of five broad-spectrum organophosphorus pesticides[J].Journal of Environmental Science and Health,Part B Pesticides,Food Contaminants,and Agricultural Wastes,2019,54(4):336-343.
[55] 李阳阳,张金波,沙君雪,等.阿特拉津降解菌LY-2的分离鉴定及其对污染土壤的修复[J].农业生物技术学报,2018,26(6):987-994.
[56] KHATOON H,RAI J P N.Optimization studies on biodegradation of atrazine by
Bacillus badius ABP6 strain using response surface methodology[J].Biotechnology Reports,2020,26:e00459.
[57] ZHANG Y H,XU D,ZHAO X H,et al.Biodegradation of two organophosphorus pesticides in whole corn silage as affected by the cultured
Lactobacillus plantarum[J].3 Biotech,2016,6(1):73.
[58] MORGAN A M,IBRAHIM M A,HUSSIEN A M.Glycyrrhizic acid modulates the atrazine-induced apoptosis in rabbit spleen[J].Environmental Science and Pollution Research,2019,26(34):34924-34930.