Effects of Butyric Acids Additives Alone or Combination with Synbiotics on Growth Performance and Gut Health of Broilers

PENG Yu; CHAI Maomao; CUI Xipeng; WANG Min; LI Yangyuan; WANG Yonghua

doi:10.3969/j.issn.1006-267x.2020.11.020

2020 , Vol. 32 >Issue 11: 5145 - 5157

DOI: https://doi.org/10.3969/j.issn.1006-267x.2020.11.020

Effects of Butyric Acids Additives Alone or Combination with Synbiotics on Growth Performance and Gut Health of Broilers

PENG Yu ,
CHAI Maomao ,
CUI Xipeng ,
WANG Min ,
LI Yangyuan ,
WANG Yonghua

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1. Guangdong VTR BIO-Tech Co., Ltd., Zhuhai 519060, China;
2. College of Food Science and Engineering, South China University of Technology, Guangzhou 510640, China

Received date: 2020-03-27

Online published: 2020-11-16

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Abstract

This study was conducted to investigate the effects of butyric acids additives alone or combination with synbiotics (SYN) to replace bacitracin zinc (BAC-Zn) on growth performance and gut health of broilers. Seven hundred and twenty 1-day-old healthy Ross 308 white-feathered broilers (males and females in half) were randomly divided into 6 groups with 6 replicates per group and 20 broilers per replicate. Broilers in control (NC) group were fed a corn-soybean meal basal diet without antibiotics, and the others in experimental groups were fed the basal diets supplemented with 10 mg/kg BAC-Zn (BAC-Zn group), 1 g/kg coated sodium butyrate (CSB, CSB group), 1 g/kg CSB+0.5 g/kg SYN (CSB+SYN group), 1 g/kg tributyrin (GTB, GTB group) and 1 g/kg GTB+0.5 g/kg SYN (GTB+SYN group). The experiment lasted for 42 days. The results showed as follows: 1) compared with groups NC and BAC-Zn, diets supplemented with GTB significantly decreased the ratio of feed to gain (F/G) of broilers at 1 to 21 days of age (P<0.05), diets supplemented with CSB significantly increased average daily feed intake (ADFI) at 22 to 42 days of age (P<0.05), and diets supplemented with CSB+SYN or GTB+SYN significantly increased average daily gain (ADG) and significantly decreased F/G at 1 to 21 days of age (P<0.05). 2) Compared with BAC-Zn group, diets supplemented with CSB, GTB or GTB+SYN significantly decreased the number of Escherichia coli in jejunal chyme of broilers, diets supplemented with GTB significantly increased the numbers of Lactobacillus in jejunal chyme and total bacteria, Firmicutes, Bacteroides, Clostridium cluster ⅪⅤa and Lactobacillus in cecal chyme (P<0.05), diets supplemented with CSB+SYN significantly increased the numbers of Clostridium cluster ⅪⅤa in jejunal chyme and Lactobacillus in jejunal and cecal chyme (P<0.05), and diets supplemented with GTB+SYN significantly increased the numbers of total bacteria and Lactobacillus in cecal chyme (P<0.05). 3) Compared with NC group, diets supplemented with CSB+SYN, GTB or GTB+SYN significantly increased the concentrations of total short-chain fatty acids (SCFAs), acetic acid and propionic acid in cecal chyme of broilers (P<0.05). Compared with BAC-Zn group, diets supplemented with GTB+SYN significantly increased the concentrations of total SCFAs and acetic acid in cecal chyme of broilers (P<0.05). 4) Compared with BAC-Zn group, diets supplemented with GTB significantly increased mRNA relative expression levels of junctional adhesion molecules 2 (JAM2) of jejunum and interleukin-2 (IL-2) of cecum of broilers (P<0.05), diets supplemented with GTB+SYN significantly increased mRNA relative expression levels of IL-2 and zonula occludens proteins-1 (ZO-1) of jejunum and ZO-1 and JAM2 of cecum (P<0.05), and diets supplemented with CSB+SYN significantly increased mRNA relative expression level of mucoprotein 2 (MUC2) of cecum (P<0.05). In summary, diets supplemented with CSB and GTB combination with SYN has a better growth-promoting effects than alone supplemented,and GTB has a better effects than CSB on promoting intestinal beneficial bacteria proliferation and SCFAs production, reducing inflammation and enhancing gut barrier, and SYN can enhance their probiotic effects.

Key words： coated sodium butyrate; tributyrin; synbiotic; white-feathered broilers; growth performance; gut health

Cite this article

PENG Yu , CHAI Maomao , CUI Xipeng , WANG Min , LI Yangyuan , WANG Yonghua . Effects of Butyric Acids Additives Alone or Combination with Synbiotics on Growth Performance and Gut Health of Broilers[J]. Chinese Journal of Animal Nutrition, 2020 , 32(11) : 5145 -5157 . DOI: 10.3969/j.issn.1006-267x.2020.11.020

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