Effects of Dietary Glutamine on Growth Performance, Immune Performance and Intestinal Mucosa Immunity of Qiandongnan Xiaoxiang Chickens

  • ZHANG Bolin ,
  • LIU Ning ,
  • LIU Rujie ,
  • GAO Zhixi ,
  • XIE Yuxiao ,
  • WANG Qingrong ,
  • ZHU Ling ,
  • ZENG Boping
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  • Key Laboratory of Conservation and Utilization of Characteristic Animal Resources in Chishui River Basin, Department of Biology and Agriculture of Zunyi Normal College, Zunyi 523006, China

Received date: 2020-03-24

  Online published: 2020-11-16

Abstract

This experiment was to investigate the effects of dietary glutamine (Gln) on growth performance, immune performance and intestinal mucosal immunity of Qiandongnan Xiaoxiang chickens. Ninety healthy 1-day-old Qiandongnan Xiaoxiang chickens with similar initial body weight were randomly allocated into three groups with five replicates per group and six chickens per replicate. Chickens in the control were fed a basal diet, and the others in experimental groups were fed basal diets supplemented with 0.5% and 1.0% Gln, respectively. The experiment lasted for 21 days. The results showed as following: 1) compared with the control group, dietary 0.5% Gln significantly increased the average daily gain, thymus index and serum immunoglobulin G (IgG) content of Qiandongnan Xiaoxiang chickens (P<0.05). 2) Compared with the control group, dietary 1.0% Gln significantly increased the average daily gain and average daily feed intake, significantly decreased the feed to gain ratio (P<0.05), significantly increased the thymus index, spleen index and bursa of Fabricius index (P<0.05), significantly increased the contents of immunoglobulin A (IgA), IgG and immunoglobulin M (IgM) in serum (P<0.05), significantly increased the content of secretory immunoglobulin A (sIgA) in jejunal mucosa (P<0.05), and significantly increased the mRNA expression levels of mucin 1 (MUC1) and mucin 2 (MUC2) in jejunal mucosa (P<0.05). 3) The average daily gain, the hymus index, spleen index and bursa of Fabricius index, the contents of IgA, IgG and IgM in serum, and the content of sIgA and mRNA expression levels of MUC1 and MUC2 in jejunal mucosa of 1.0% Gln supplementation group were significantly higher than those of 0.5% Gln supplementation group (P<0.05). In conclusion, dietary 1.0% Gln can improve the growth performance, immune performance and intestinal immune capacity of Qiandongnan Xiaoxiang chickens.

Cite this article

ZHANG Bolin , LIU Ning , LIU Rujie , GAO Zhixi , XIE Yuxiao , WANG Qingrong , ZHU Ling , ZENG Boping . Effects of Dietary Glutamine on Growth Performance, Immune Performance and Intestinal Mucosa Immunity of Qiandongnan Xiaoxiang Chickens[J]. Chinese Journal of Animal Nutrition, 2020 , 32(11) : 5158 -5166 . DOI: 10.3969/j.issn.1006-267x.2020.11.021

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