Effects of Artemisia argyi Ethanol Extract on Growth Performance, Immunity and Antioxidant Indexes in Liver and Spleen of Broilers

ZHANG Jing; YANG Shuo; XING Yuanyuan; DU Haidong; JIANG Yang; XU Yuanqing; JIN Xiao; SHI Binlin

doi:10.3969/j.issn.1006-267x.2020.11.024

2020 , Vol. 32 >Issue 11: 5185 - 5194

DOI: https://doi.org/10.3969/j.issn.1006-267x.2020.11.024

Effects of Artemisia argyi Ethanol Extract on Growth Performance, Immunity and Antioxidant Indexes in Liver and Spleen of Broilers

ZHANG Jing ,
YANG Shuo ,
XING Yuanyuan ,
DU Haidong ,
JIANG Yang ,
XU Yuanqing ,
JIN Xiao ,
SHI Binlin

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College of Animal Science, Inner Mongolia Agricultural University, Hohhot 010018, China

Received date: 2020-04-29

Online published: 2020-11-16

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Abstract

The aim of this study was to investigate the effects of Artemisia argyi ethanol extract (AAEE) on growth performance, immunity and antioxidant indexes in liver and spleen of broilers. Using completely randomized trial design, two hundred and forty Arbor Acres broilers (1 day of age) were selected and randomly allotted to 5 groups, and each replicate with 8 broilers (half males and half females). Basal diet supplemented with 0 (control), 250, 500, 750, and 1 000 mg/kg of AAEE were constituted the experiment diets, respectively. The experiment lasted for 42 days. The results showed as follows: 1) at 42 days of age, the final body weight of broilers in 750 mg/kg AAEE group was significantly higher than that in the control group (P<0.01) and increased linearly (P=0.094). Adding 500 and 750 mg/kg AAEE significantly decreased the total feed intake (FI) compared with the control group (P<0.05). Moreover, total FI linearly (P=0.071) or quadratically decreased (P=0.075) with the supplementation of AAEE. 2) At 42 days of age, dietary supplementation of 500 and 750 mg/kg AAEE significantly increased catalase (CAT) activity in liver (P<0.05) and significantly increased total antioxidant capacity (T-AOC) (P<0.01) compared with the control group, and both of them linearly (P<0.05) or quadratically (P<0.01) increased in the liver. In spleen of broilers, compared with the control group, adding 750 mg/kg AAEE significantly increased the T-AOC and the activities of CAT and total superoxide dismutase (T-SOD) (P<0.01). And all above indexes linearly or quadratically (P<0.01) increased at 21 days of age. Adding 750 mg/kg AAEE significantly increased CAT activity (P<0.01) and T-AOC (P<0.05) in spleen, and significantly decreased malondialdehyde (MDA) content (P<0.05) compared with the control group at 42 days of age. In addition, CAT linearly or quadratically increased (P<0.01). 3) In the liver of broilers, 500 and 750 mg/kg AAEE significantly reduced interleukin-1β (IL-1β) (P<0.01) and interleukin-6 (IL-6) (P<0.05) contents in liver compared with the control group, and both of them quadratically decreased (P<0.01) at 42 days of age. In the spleen of broilers, compared with the control group, adding 500 and 750 mg/kg AAEE significantly reduced IL-1β and IL-6 contents (P<0.05) at 21 days of age. In addition, IL-1β contents quadratically decreased (P<0.05). Compared with the control group, adding 750 and 1 000 mg/kg AAEE significantly increased interleukin-2 (IL-2) and interleukin-4 (IL-4) (P<0.01) contents, and both of them linearly or quadratically increased (P<0.01) at 21 days of age. Adding 750 mg/kg AAEE, IL-1β content was not only significantly lower than that in the control group (P<0.05), but also quadratically decreased (P<0.05) at 42 days of age. In conclusion, the addition of 750 mg/kg AAEE is more beneficial to the growth and improvement of antioxidant and immune function of broilers.

Key words： Artemisia argyi ethanol extract; growth performance; immune index; antioxidant index

Cite this article

ZHANG Jing , YANG Shuo , XING Yuanyuan , DU Haidong , JIANG Yang , XU Yuanqing , JIN Xiao , SHI Binlin . Effects of Artemisia argyi Ethanol Extract on Growth Performance, Immunity and Antioxidant Indexes in Liver and Spleen of Broilers[J]. Chinese Journal of Animal Nutrition, 2020 , 32(11) : 5185 -5194 . DOI: 10.3969/j.issn.1006-267x.2020.11.024

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