Effects of β-glucan on Growth Performance, Immune Organ Indexes, Serum Biochemical and Immune Indexes of Meat Rabbits

  • LI Yanping ,
  • ZHAN Haijie ,
  • ZHENG Jianting ,
  • CAO Liang ,
  • FENG Guoliang ,
  • NIU Xiaoyan ,
  • REN Keliang
Expand
  • College of Animal Science, Shanxi Agricultural University, Taiyuan 030032, China

Received date: 2020-08-04

  Online published: 2020-11-16

Abstract

This experiment was to investigate the effects of dietary different levels of β-glucan on growth performance, immune organ indexes, serum biochemical and immune indexes of meat rabbits. A total of 240 thirty-five-day-old weaned Hyla commercial rabbits with similar weight were randomly divided into 4 groups with 60 replicates in each group and 1 rabbit in each replicate. Rabbits in the control group were fed a basal diet, and others in experimental group Ⅰ, experimental group Ⅱ and experimental group Ⅲ were fed basal diets supplemented with 0.03%, 0.05% and 0.07% β-glucan, respectively. The pretrial period was 5 days, and the experiment period was 22 days. The results showed as follows: 1) compared with the control group, the average daily feed intake of experimental group Ⅱ, experimental group Ⅰ and experimental group Ⅲ was increased by 2.89% (P<0.05), 1.49% (P>0.05) and 1.14% (P>0.05), respectively; and the average daily gain of experimental group Ⅱ, experimental group Ⅲ and experimental group Ⅰ was increased by 5.80% (P<0.05), 3.20% (P>0.05) and 1.72% (P>0.05), respectively. 2) The thymus index of experimental group Ⅱ was significantly higher than that of the control group (P<0.01), and the cysts index was significantly higher than that of the control group (P<0.05). 3) The serum albumin (ALB) content of experimental group Ⅲ was significantly lower than that of the control group (P<0.01), the serum glucose oxidase (GOD) activity of experimental group Ⅰ was significantly higher than that of the control group (P<0.01), and the activities of alanine aminotransferase (ALT) and aspartate aminotransferase (AST) in serum of experimental group Ⅱ and experimental group Ⅲ were significantly lower than those of experimental group Ⅰ and control group (P<0.05 or P<0.01). 4) The serum immunoglobulin A (IgA) content of experimental group Ⅱ was significantly higher than that of the control group (P<0.01), the serum immunoglobulin G (IgG) content of experimental group Ⅰ and experimental group Ⅱ was significantly higher than that that of the control group (P<0.01), the serum immunoglobulin M (IgM) content of experimental group Ⅰ and experimental group Ⅱ was significantly lower than that of the control group (P<0.05), and the serum interleukin-6 (IL-6) content of experimental group Ⅱ was significantly lower than that that of the control group (P<0.01). In summary, dietary β-glucan can improve the average daily feed intake and average daily gain of meat rabbits, increase the immune organ index, improve the body immunity and digestion, absorption and metabolism ability. In the experiments, dietary suitable β-glucan supplemental level is 0.05%.

Cite this article

LI Yanping , ZHAN Haijie , ZHENG Jianting , CAO Liang , FENG Guoliang , NIU Xiaoyan , REN Keliang . Effects of β-glucan on Growth Performance, Immune Organ Indexes, Serum Biochemical and Immune Indexes of Meat Rabbits[J]. Chinese Journal of Animal Nutrition, 2020 , 32(11) : 5365 -5372 . DOI: 10.3969/j.issn.1006-267x.2020.11.042

References

[1] PILLEMER L,ECKER E E.Anticomplementary factor in fresh yeast[J].The Journal of Biological Chemistry,1941,137(1):139-142.
[2] PILLEMER L,SCHOENBERG M D,BLUM L,et al.Properdin system and immunity:Ⅱ.Interaction of the properdin system with polysaccharides[J].Science,1955,122(3169):545-549.  
[3] 郑娟善,丁保安.β-1,3/1,6-葡聚糖在畜禽日粮中的应用效果[J].中国畜牧兽医,2018,45(6):1571-1579.
[4] 杨泰,杨媚,邓圣庭,等.β-1,3/1,6-葡聚糖的免疫调控机理及其在畜牧生产中的应用[J].动物营养学报,2019,31(8):3463-3472.
[5] 刘影,呙于明,袁建敏,等.β-1,3/1,6-葡聚糖对肉仔鸡生产性能和免疫功能的影响[J].中国农业大学学报,2003,8(1):91-94.
[6] 刘杰.β-1,3-葡聚糖对断奶仔猪生产性能、肠道健康及免疫功能的影响[D].硕士学位论文.雅安:四川农业大学,2016.
[7] 何凤琴,胡雪静,高智华,等.β-葡聚糖对蛋鸡生产性能、蛋品质及免疫指标的影响[J].畜牧与饲料科学,2011,32(5):1-3.
[8] 任克良.家兔配合饲料生产技术[M].北京:金盾出版社,2002.
[9] LEBAS F.Nutrient requirements of rabbits[J].Journal of Applied Rabbit Research,1998,3:14-16.
[10] HISS S,SAUERWEIN H.Influence of dietary β-glucan on growth performance,lymphocyte proliferation,specific immune response and haptoglobin plasma concentrations in pigs[J].Journal of Animal Physiology and Animal Nutrition,2003,87(1/2):2-11.
[11] LEI X J,YUN H M,YANG Y,et al.Growth performance,nutrient digestibility,and selected fecal microbiota are improved by β-glucan supplementation in weaner pigs[J].Annals of Animal Science,2018,18(3):769-779.  
[12] WANG Z,GUO Y M,YUAN J M,et al.Effect of dietary β-1,3/1,6-glucan supplementation on growth performance,immune response and plasma prostaglandin E2,growth hormone and ghrelin in weanling piglets[J].Asian-Australasian Journal of Animal Sciences,2008,21(5):707-714.  
[13] 周怿.酵母β-葡聚糖对早期断奶犊牛生长性能及胃肠道发育的影响[D].博士学位论文.北京:中国农业科学院,2010.
[14] 曲昆鹏,张倩,杨家昶,等.β-葡聚糖对肉仔鸡生长性能、免疫功能和肠道微环境的影响[J].动物营养学报,2016,28(7):2235-2242.
[15] CHO J H,ZHANG Z F,KIM I H.Effects of single or combined dietary supplementation of β-glucan and kefir on growth performance,blood characteristics and meat quality in broilers[J].British Poultry Science,2013,54(2):216-221.  
[16] 刘金艳,王瑶,毛俊霞,等.日粮添加β-葡聚糖对仔猪生长性能、肠道发育与免疫功能的影响[J].中国兽医学报,2017,37(11):2197-2205.
[17] 安尚泽,汪岩,王雷,等.β-葡聚糖对仔猪生长性能和肠道黏膜形态的影响[J].延边大学农学学报,2012,34(1):79-82,92.
[18] 刘环,佘锐萍,宋俊霞,等.兔圆小囊免疫功能及其与肠道黏膜局部免疫关系的研究Ⅳ.实验性感染肠球虫兔的圆小囊上皮间淋巴细胞及杯状细胞定量观察[J].畜牧兽医学报,1997,28(5):448-452.
[19] SHETH S G,MANI S,TAMHANKAR H,et al.Spleen size in health and disease:a sonographic assessment[J].Journal of Association of Physicians of India,1995,43(3):182-184.
[20] 张敬,潘振亮,李鹏,等.酵母源β-葡聚糖对肉仔鸡生长性能和免疫功能的影响[J].天津农业科学,2008,14(6):5-8.
[21] 汪岩,安尚泽,姜贺,等.β-葡聚糖对小鼠非特异性免疫性能的影响[J].饲料研究,2012(6):32-33,35.
[22] 李华伟,姬玉娇,张婷,等.发酵中药渣对围产期母猪和哺乳仔猪血浆生化参数和抗氧化指标的影响[J].天然产物研究与开发,2017,29(9):1580-1586.
[23] 武静龙.复合酶制剂对獭兔生产性能和血清生理生化指标的影响[D].硕士学位论文.长沙:湖南农业大学,2006.
[24] 胡泉舟,侯永清,王猛.血中二胺氧化酶活性与仔猪腹泻程度的相关性分析[J].猪业科学,2007,24(12):73-74.
[25] 李芹,唐洪玉.中华倒刺鲃仔稚鱼期消化酶及碱性磷酸酶活性变化的研究[J].水生态学杂志,2010,3(5):82-85.
[26] 刘乙发.根据血清谷草转氨酶与谷丙转氨酶比值对重型肝炎进行预后分析[J].湘南学院学报(自然科学版),2004,6(3):45-46.
[27] 刘玮,韩海霞,曹顶国,等.α-多肽菌素对科宝500肉鸡生产性能、免疫指标、血清生化指标和抗氧化性能的影响[J].中国家禽,2018,40(4):29-35.
[28] 李燕舞,姜八一,刘建胜,等.杜仲叶提取物对肉兔生长性能及血清生化、免疫与抗氧化指标的影响[J].动物营养学报,2019,31(2):824-830.
[29] GROSS O,POECK H,BSCHEIDER M,et al.Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence[J].Nature,2009,459(7245):433-436.  
[30] GRINGHUIS S I,KAPTEIN T M,WEVERS B A,et al.Dectin-1 is an extracellular pathogen sensor for the induction and processing of IL-1β via a noncanonical caspase-8 inflammasome[J].Nature Immunology,2012,13(3):246-254.  
[31] SANCHO D,REIS E SOUSA C.Signaling by myeloid C-type lectin receptors in immunity and homeostasis[J].Annual Review of Immunology,2012,30:491-529.
[32] SHAO Y J,WANG Z,TIAN X Y,et al.Yeast β-D-glucans induced antimicrobial peptide expressions against Salmonella infection in broiler chickens[J].International Journal of Biological Macromolecules,2016,85:573-584.
[33] HOFER M,POSPÍŠIL M.Glucan as stimulator of hematopoiesis in normal and gamma-irradiated mice.a survey of the authors' results[J].International Journal of Immunopharmacology,1997,19(9/10):607-609.
[34] 史酉川,郑云朵,李昂,等.啤酒酵母对生长獭兔免疫性能及抗氧化能力的影响[J].中国饲料,2017(19):17-20.
Outlines

/