Physiological Regulation Mechanism of Tributyrin and Its Application in Animal Production

  • XUE Yongqiang ,
  • MA Yongxi ,
  • ZHAO Hu ,
  • YANG Bo
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  • 1. School of Biology and Biological Engineering, South China University of Technology, Guangzhou 510006, China;
    2. Guangdong Provincial Research Center for Lipid Science and Applied Engineering Technology, Guangzhou 510006, China;
    3. Ministry of Agriculture Feed Industry Centre, China Agricultural University, Beijing 100193, China

Received date: 2020-04-15

  Online published: 2020-12-07

Abstract

Tributyrin, as the esterification product of butyric acid and glycerol, is decomposed into butyric acids and glycerin by pancreatic lipase in the animal gastrointestinal tract, and then transported to various tissues and organs to exert a physiological role. For instance, tributyrin maintains intestinal integrity, regulates intestinal microbiota, participates in immune regulation and energy metabolism and so on. Meanwhile, given that its various physiological function and safety, the tributyrin can be used as a potential alternative for antibiotics in animal production. This paper reviewed physicochemical properties, metabolic pathways, physiological functions, molecular mechanisms and their application in animal production, aiming to provide a theoretical reference for exploring its application in animal production.

Cite this article

XUE Yongqiang , MA Yongxi , ZHAO Hu , YANG Bo . Physiological Regulation Mechanism of Tributyrin and Its Application in Animal Production[J]. Chinese Journal of Animal Nutrition, 2020 , 32(12) : 5547 -5555 . DOI: 10.3969/j.issn.1006-267x.2020.12.008

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