Effects of Nutritional Restriction during Late Gestation on Biogenic Amine Neurotransmitters of Mongolian Sheep Fetus

  • QIN Yulong ,
  • MA Chi ,
  • YANG Huan ,
  • ZI Yang ,
  • QIAO Yina ,
  • LIU Yingchun ,
  • GAO Feng
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  • 1. College of Animal Science, Inner Mongolia Agricultural University, Hohhot 010018, China;
    2. College of Life Science, Inner Mongolia Agricultural University, Hohhot 010018, China

Received date: 2020-06-03

  Online published: 2021-01-18

Abstract

The purpose of this study was to investigate the effects of nutritional restriction during late gestation on biogenic amine neurotransmitters of Mongolian sheep fetus. Eighteen Mongolian sheep with synchronization of estrus and conception were randomly divided into three groups at day 90 of gestation: nutritional restriction group 1 [NG1 group, n=6, metabolizable energy (ME)=0.175 MJ/(kg BW0.75·d)], nutritional restriction group 2 [NG2 group, n=6, metabolizable energy (ME)=0.330 MJ/(kg BW0.75·d)] and control group [CG group, n=6, metabolizable energy (ME)=0.670 MJ/(kg BW0.75·d)].All sheep were slaughtered at 140 days of gestation, and the fetuses and their brain tissues and blood were sampled. The results showed that the fetal brain weight of NG1 group was significantly higher than that of CG group (P<0.05), and the contents of 5-hydroxytryptamine (5-HT) (P<0.01) and epinephrine (EPI) (P<0.05) were significantly or extremely significantly higher than those of CG group, while the content of noradrenaline (NA) was extremely significantly lower than that of CG group (P<0.01). The content of 5-HT in fetal brain of NG2 group was extremely significantly higher than that of CG group (P<0.01), while the content of NA (P<0.01) and dopamine (DA) (P<0.05) were significantly lower than those of CG group. In addition, the contents of 5-HT (P<0.01), EPI (P<0.01), NA (P<0.05) and DA (P<0.01) in fetal plasma of NG1 group were significantly or extremely significantly lower than those of CG group; the contents of 5-HT (P<0.01), NA (P<0.01) and DA (P<0.05) in fetal plasma of NG2 group were significantly or extremely significantly lower than those of CG group. In conclusion, nutritional restriction during late gestation makes the contents 5-HT, EPI increasing and the content of NA decreasing in Mongolian sheep fetal brain, as well as makes the contents of 5-HT, EPI, NA and DA decreasing in fetal brain.

Cite this article

QIN Yulong , MA Chi , YANG Huan , ZI Yang , QIAO Yina , LIU Yingchun , GAO Feng . Effects of Nutritional Restriction during Late Gestation on Biogenic Amine Neurotransmitters of Mongolian Sheep Fetus[J]. Chinese Journal of Animal Nutrition, 2021 , 33(1) : 390 -396 . DOI: 10.3969/j.issn.1006-267x.2021.01.039

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