Biological Function, Expression Characteristics and Regulation Mechanism of Host Defense Peptides

  • DOU Xiujing ,
  • ZHANG Jiayi ,
  • WANG Yiru ,
  • SHAN Anshan
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  • College of Animal Science and Technology, Northeast Agricultural University, Harbin 150038, China

Received date: 2020-06-15

  Online published: 2021-02-04

Supported by

 

Abstract

As an important component of the innate immune defense system, the host defense peptides (HDPs) have various biological functions such as antibacterial, antiviral, antiparasitic, and immune regulation. The expression level of the HDPs in the animal body can be regulated by various factors. Therefore, a thorough study of the expression characteristics of the HDPs is of great significance to induce its expression to strengthen organism immunity and resist against pathogens and microbial infection. In this paper, the concept, classification, biological function, expression characteristics and regulation mechanism of HDPs were reviewed, providing an important theoretical basis for regulating its expression through diet as an alternative to forage antibiotics in animal production.

Cite this article

DOU Xiujing , ZHANG Jiayi , WANG Yiru , SHAN Anshan . Biological Function, Expression Characteristics and Regulation Mechanism of Host Defense Peptides[J]. Chinese Journal of Animal Nutrition, 2021 , 33(2) : 601 -613 . DOI: 10.3969/j.issn.1006-267x.2021.02.001

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