Effects of Multivitamin Nanoemulsion on Growth Performance, Immune Function, Antioxidant Ability, Intestinal Tissue Structure and Cecal Microecology of Growing Rex Rabbits

  • YE Xiangyang ,
  • GONG Ruiguang ,
  • REN Zhanjun
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  • 1. College of Animal Science and Technology, Northwester A & F University, Yangling 712100, China;
    2. Guangdong Key Laboratory of Animal Breeding and Nutrition, Key Laboratory of Animal Nutrition and Feed Science in South China, Ministry of Agriculture and Rural Affairs, State Key Laboratory of Animal and Poultry Breeding, Institute of Animal Science, Guangdong Academy of Agricultural Sciences, Guangzhou 510640, China

Received date: 2020-06-13

  Online published: 2021-02-04

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Abstract

The aim of this experiment was to investigate the effects of multivitamin nanoemulsion on growth performance, immune function, antioxidant ability, intestinal tissue structure and cecal microecology of growing Rex rabbits. A total of 150 healthy weaned Rex rabbits at the age of 30 days and similar body weight were selected, and randomly divided into 5 groups with 3 repetitions in each group and 10 rabbits (half male and half female) in each repetition. Rabbits in control group Ⅰ were fed a granulated feed containing vitamins (100% nutritional standard), normal drinking water; rabbits in control group Ⅱ fed the same granulated feed with control group Ⅰ, but the drinking water added Twain-80+glycerol (the contents of them were the same as test group Ⅱ); rabbits in test groups were fed the granulated feed without vitamins, and test groups Ⅰ, Ⅱ and Ⅲ were added multivitamin nanoemulsion including 80%, 100% and 120% nutritional standard vitamins in drinking water. The experiment lasted for 61 days including a 5-day preliminary period and a 56-day test period. The results showed as follows: compared with control group Ⅰ, 1) on day 1 to 28, the diarrhea rate and diarrhea mortality were significantly reduced in control group Ⅱ and test group Ⅰ (P<0.05), on day 29 to 56, the average daily feed intake was significantly reduced in test groups Ⅱ and Ⅲ (P<0.05), while the feed/gain was not significant difference (P>0.05); 2) the thymus index was significantly reduced in test groups Ⅰ and Ⅱ(P<0.05), the appendix length was significantly reduced in control group Ⅱ and test group Ⅱ (P<0.05), and the liver index was significantly increased in test groups Ⅰ and Ⅲ (P<0.05); 3) the blood total antioxidant capacity in test group Ⅱ and blood superoxide dismutase activity in control group Ⅱ were significantly increased (P<0.05); 4) the villus height of ileum was significantly increased in control group Ⅱ (P<0.01), the crypt depth of ileum was significantly reduced in test group Ⅰ (P<0.05), and the villus height/crypt depth of ileum was significantly increased in all test groups and control group Ⅱ (P<0.01), the lymphocyte cell proportion in simple columnar epithelium of ileum was significantly increased in control group Ⅱ(P<0.05); 5) the relative abundances of Firmicutes, Ruminococcaceae and Ruminococcaceae UCG-014 in cecum were significantly reduced in test group Ⅱ (P<0.05). It is concluded that adding multivitamin nanoemulsion containing the nutritional standard of 100% into the drinking water can enhance the immune function and antioxidant ability, improve the intestinal tissue structure and cecal microecology of growing Rex rabbits.

Cite this article

YE Xiangyang , GONG Ruiguang , REN Zhanjun . Effects of Multivitamin Nanoemulsion on Growth Performance, Immune Function, Antioxidant Ability, Intestinal Tissue Structure and Cecal Microecology of Growing Rex Rabbits[J]. Chinese Journal of Animal Nutrition, 2021 , 33(2) : 1044 -1054 . DOI: 10.3969/j.issn.1006-267x.2021.02.044

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