Effects of Yeast Polysaccharide on Growth Performance, Intestinal Morphology and Intestinal Immune Status of Weaned Piglets

WU Yuliang; PENG Changfeng; CUI Zhijuan; XIONG Xia; XIAO Dingfu; LI Biao; YIN Yulong

doi:10.3969/j.issn.1006-267x.2021.03.018

2021 , Vol. 33 >Issue 3: 1349 - 1358

DOI: https://doi.org/10.3969/j.issn.1006-267x.2021.03.018

Effects of Yeast Polysaccharide on Growth Performance, Intestinal Morphology and Intestinal Immune Status of Weaned Piglets

WU Yuliang ,
PENG Changfeng ,
CUI Zhijuan ,
XIONG Xia ,
XIAO Dingfu ,
LI Biao ,
YIN Yulong

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1. College of Animal Science, Hunan Agricultural University, Changsha 410128, China;
2. Key Laboratory of Animal Nutritional Physiology and Metabolic Process of Hunan, Institute of Subtropical Agriculture, Chinese Academy of Sciences, Changsha 410125, China;
3. Angel Yeast Co., Ltd., Yichang 443000, China

Received date: 2020-07-24

Online published: 2021-03-18

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Abstract

This study was conducted to investigate the effects of yeast polysaccharide on growth performance, intestinal morphology, antioxidant capacity and intestinal immune status of weaned piglets. Thirty-two healthy Landrace×Yorkshire×Duroc castrated male weaned piglets at 21-day-old with similar body weight of (6.89±0.88) kg were randomly divided into 4 groups with 8 replicates per group and 1 pig per replicate. Pigs in control group were fed a basal diet, and the others in experimental groups were fed the basal diets supplemented with 0.1% yeast polysaccharide (0.1% yeast polysaccharide group), 0.2% yeast polysaccharide (0.2% yeast polysaccharide group) and 55 mg/kg kitasamycin and 20 mg/kg colistin sulfate (antibiotic group). The pretest lasted for 3 days, and the test lasted for 28 days. The results showed as follows: compared with control group, 1) diet supplemented with 0.1% yeast polysaccharide significantly increased average daily gain and average daily feed intake of weaned piglets (P<0.05), and significantly decreased pH of cecal content (P<0.05). Diet supplemented with 0.1% and 0.2% yeast polysaccharide and antibiotic significantly deceased the ratio of feed to gain (P<0.05). 2) Diet supplemented with 0.1% and 0.2% yeast polysaccharide had a tendency to increase jejunal villus height of weaned pigs (0.05<P<0.10). The number of ileal intraepithelial lymphocytes in 0.1% yeast polysaccharide and antibiotic group was significantly increased (P<0.05). 3) Diet supplemented with 0.2% yeast polysaccharide and antibiotic significantly decreased the activity of superoxide dismutase (SOD) in duodenal mucosa of weaned pigs (P<0.05). Diet supplemented with 0.1% and 0.2% yeast polysaccharide and antibiotic significantly decreased the activity of SOD in jejunal mucosa of weaned pigs (P<0.05). 4) The expression level of interleukin-6 (IL-6) mRNA in duodenal mucosa of weaned pigs in 0.2% yeast polysaccharide group was significantly decreased (P<0.05), and the expression level of interleukin-10 (IL-10) mRNA in ileal mucosa in 0.2% yeast polysaccharide group was significantly increased (P<0.05). The expression level of tumor necrosis factor-α (TNF-α) mRNA in jejunal mucosa in 0.1% and 0.2% yeast polysaccharide and antibiotic groups had a tendency to reduce (0.05 < P < 0.10). It is concluded that yeast polysaccharide can improve growth performance of weaned piglets, reduce the pH value in cecum, improve intestinal morphology and reduce intestinal inflammation. Under the conditions of this experiment, the appropriate supplemented level of yeast polysaccharide in piglet’s diets was 0.1%.

Key words： yeast polysaccharide; weaned piglets; intestinal morphology; immune function

Cite this article

WU Yuliang , PENG Changfeng , CUI Zhijuan , XIONG Xia , XIAO Dingfu , LI Biao , YIN Yulong . Effects of Yeast Polysaccharide on Growth Performance, Intestinal Morphology and Intestinal Immune Status of Weaned Piglets[J]. Chinese Journal of Animal Nutrition, 2021 , 33(3) : 1349 -1358 . DOI: 10.3969/j.issn.1006-267x.2021.03.018

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