Regulation and Mechanism of Choline on Liver Glycometabolism

  • WANG Honghao ,
  • LIU Zhejia ,
  • YAO Junhu ,
  • CAO Yangchun
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  • College of Animal Science and Technology, Northwest A&F University, Yangling 712100, China

Received date: 2020-08-14

  Online published: 2021-04-15

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Abstract

Choline is an essential nutrient in animal diets. It exists in various forms in the animal body and can participate in the synthesis of acetylcholine, phosphatidylcholine and methyl donors through the pathways of acetate, phosphorylation and oxidation, respectively. And it also can improve the level of animal glycometabolism. Based on the existing relevant literature, we focused on the research progress of choline regulating liver glucose metabolism in animals, and clarified the effect of choline on liver gluconeogenesis, glucose oxidation metabolism, antioxidant capacity and glucose metabolism diseases, which involved several signaling pathways for glycometabolism. Finally, we combined these signaling pathways to form a regulation network. This review aimed to provide the reference for animal husbandry and scientific research.

Cite this article

WANG Honghao , LIU Zhejia , YAO Junhu , CAO Yangchun . Regulation and Mechanism of Choline on Liver Glycometabolism[J]. Chinese Journal of Animal Nutrition, 2021 , 33(4) : 1913 -1924 . DOI: 10.3969/j.issn.1006-267x.2021.04.012

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