Effects of Serine Supplementation in Diets for Perinatal Sows on Serum Biochemical Indices and Antioxidant Function of Lactating Sows and Suckling Piglets

  • ZENG Sijing ,
  • LIU Yonghui ,
  • LONG Jing ,
  • GUAN Peng ,
  • HU Xian ,
  • WANG Chenyu ,
  • HE Liuqin ,
  • LI Tiejun ,
  • DENG Jinping ,
  • YIN Yulong
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  • 1. College of Animal Science, South China Agricultural University, Guangzhou 510462, China;
    2. Key Laboratory of Animal Nutritional Physiology and Metabolic Process of Hunan, Institute of Subtropical Agriculture, Chinese Academy of Sciences, Changsha 410125, China;
    3. Hunan International Joint Laboratory of Animal Intestinal Ecology and Health, Laboratory of Animal Nutrition and Human Health, Hunan Provincial Key Laboratory of Animal Intestinal Function and Regulation, College of Life Sciences, Hunan Normal University, Changsha 410081, China;
    4. University of Chinese Academy of Sciences, Beijing 101408, China

Received date: 2020-09-23

  Online published: 2021-04-15

Supported by

 

Abstract

This experiment aimed to investigate the effects of serine (Ser) supplementation in diets for perinatal sows on serum biochemical indices and antioxidant function of lactating sows and suckling piglets. One hundred crossbreds (Landrace×Yorkshire) healthy sows with similar parity and body condition at the 85th day of gestation were assigned into following 4 groups with 25 sows per group, and each of them was raised in a single column. Based on the basal diet, the supplementations of 0 (control group), 25% (L-Ser group), 50% (M-Ser group) and 100% (H-Ser group) of basal diet Ser content were added into the basal diet. For control group, L-Ser group, M-Ser group and H-Ser group, the Ser content of sows' diets during late pregnant period and lactating period was 0.55% and 0.66%, 0.69% and 0.83%, 0.83% and 0.99%, 1.10% and 1.32%, respectively. Feeding trial from the 85th day of gestation to 21 days of weaning. The results showed as follows:1) serum total protein (TP) content of lactating sows in M-Ser group was significantly lower than that in other groups (P<0.05). Colostrum Ser, glycine (Gly) and cysteine (Cys) contents in M-Ser group were significantly higher than those in L-Ser group (P<0.05). 2) For 21-day-old suckling piglets, supplemented different levels of Ser in diets for perinatal sows had no significant effects on the activities of alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP) and the contents of urea nitrogen (UN) and glucose (GLU) in serum (P>0.05); but serum Ser content in H-Ser group was significantly higher than that in other three groups (P<0.01), and serum Gly and Cys contents in L-Ser group were significantly higher than those in control group(P<0.05). 3) For lactating sows, serum malondialdehyde (MDA) content in M-Ser group was significantly lower than that in other three groups (P<0.01), and serum glutathione peroxidase (GPx) activity in M-Ser group and H-Ser group was significantly higher than that in control group and L-Ser group (P<0.01); for 21-day-old suckling piglets, serum MDA content in the three Ser supplementation groups was significantly lower than that in control group (P<0.05), at the same time, the jejunal mRNA expression levels of glutamate-cysteine ligase modifier subunit (GCLM)and GPx4 were significantly increased in M-Ser group and L-Ser group compared with control group (P<0.05). In general, adding suitable level of Ser in diets for perinatal sows to make the Ser content in sows' diets during late pregnant period and lactating period is 0.83% and 0.99%, respectively, can increase the antioxidant capacity of lactating sows. More importantly, this benefit may be conveyed to piglets through breast nursing.

Cite this article

ZENG Sijing , LIU Yonghui , LONG Jing , GUAN Peng , HU Xian , WANG Chenyu , HE Liuqin , LI Tiejun , DENG Jinping , YIN Yulong . Effects of Serine Supplementation in Diets for Perinatal Sows on Serum Biochemical Indices and Antioxidant Function of Lactating Sows and Suckling Piglets[J]. Chinese Journal of Animal Nutrition, 2021 , 33(4) : 1976 -1985 . DOI: 10.3969/j.issn.1006-267x.2021.04.018

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