Research Progress of Exogenous Melatonin in Alleviating Heat Stress in Dairy Cow and Buffalo

  • WANG Zichen ,
  • LIN Feng ,
  • GAO Tengyun ,
  • LIU Shenhe
Expand
  • Institute of Animal Science and Technology, Henan Agricultural University, Zhengzhou 450046, China

Received date: 2020-10-22

  Online published: 2021-05-14

Supported by

 

Abstract

Cattle industry is restricted by heat stress in summer. Melatonin as an antioxidant and free radical scavenger can effectively alleviate heat stress. This review discusses the application effect of exogenous melatonin on relieving heat stress in dairy cow and buffalo, and explaining the mechanism of its protective effect on heat-induced animal cell damage, in order to provide theoretical basis and technical support for the application of exogenous melatonin in alleviating heat stress in dairy cow and buffalo in summer.

Cite this article

WANG Zichen , LIN Feng , GAO Tengyun , LIU Shenhe . Research Progress of Exogenous Melatonin in Alleviating Heat Stress in Dairy Cow and Buffalo[J]. Chinese Journal of Animal Nutrition, 2021 , 33(5) : 2495 -2503 . DOI: 10.3969/j.issn.1006-267x.2021.05.010

References

[1] MIN L,LI D G,TONG X,et al.Nutritional strategies for alleviating the detrimental effects of heat stress in dairy cows:a review[J].International Journal of Biometeorology,2019,63(9):1283-1302.  
[2] MANCHESTER L C,COTO-MONTES A,BOGA J A,et al.Melatonin:an ancient molecule that makes oxygen metabolically tolerable[J].Journal of Pineal Research,2015,59(4):403-419.  
[3] BECKER C A,STONE A E.Graduate student literature review:heat abatement strategies used to reduce negative effects of heat stress in dairy cows[J].Journal of Dairy Science,2020,103(10):9667-9675.  
[4] ST-PIERRE N R,COBANOV B,SCHNITKEY G D.Economic losses from heat stress by US livestock industries[J].Journal of Dairy Science,2003,86(Suppl.1):E52-E77.
[5] 杜海燕,王守红,黄薇薇.褪黑素保护卵母细胞应对热应激损伤的研究[J].生殖医学杂志,2019,28(5):531-535. DU H Y,WANG S H,HANG W W.Study on melatonin protecting oocytes from heat stress damage[J].Journal of Reproductive Medicine,2019,28(5):531-535.(in Chinese)
[6] 邵钺馨,单春花,王超,等.奶牛生产中冷热应激的研究进展[J].黑龙江畜牧兽医,2018(7):38-41. SHAO Y X,SHAN C H,WANG C,et al.Research progress of cold and heat stress in dairy cow production[J].Heilongjiang Animal Science and Veterinary Medicine,2018(7):38-41.(in Chinese)
[7] 单强,马峰涛,魏婧雅,等.热应激影响荷斯坦奶牛泌乳机制的研究进展[J].中国畜牧杂志,2019,55(3):29-33. SHAN Q,MA J T,WEI J Y,et al.Research progress on the effect of heat stress on the lactation mechanism of Holstein dairy cows[J]Chinese Journal of Animal Science,2019,55(3):29-33.(in Chinese)
[8] ROTH Z,AROYO A,YAVIN S,et al.The antioxidant epigallocatechin gallate (EGCG) moderates the deleterious effects of maternal hyperthermia on follicle-enclosed oocytes in mice[J].Theriogenology,2008,70(6):887-897.  
[9] GARCIA J J,LOPEZ-PINGAMON L,ALMEIDA-SOUZA P,et al.Protective effects of melatonin in reducing oxidative stress and in preserving membrane viscosity[J].Journal of Pineal Research,2014;56:225-237.
[10] REITER R J.Oxidative processes and antioxidative defense mechanisms in the aging brain[J].The FASEB Journal,1995,9(7):526-533.  
[11] ACUÑA-CASTROVIEJO D,ESCAMES G,VENEGAS C,et al.Extrapineal melatonin:sources,regulation,and potential functions[J].Cellular and Molecular Life Sciences,2014,71(16):2997-3025.  
[12] 刘森,李海涛.褪黑素在牛、羊生产中的应用[J].中国畜牧兽医文摘,2016,32(12):53,78. LIU S,LIU H T.Application of melatonin in cattle and sheep production[J].Chinese Abstracts of Animal Husbandry and Veterinary Medicine,2016,32(12):53,78.(in Chinese)
[13] PANG Y W,JIANG X L,ZHAO S J,et al.Beneficial role of melatonin in protecting mammalian gametes and embryos from oxidative damage[J].Journal of Integrative Agriculture,2018,17(10):2320-2335.  
[14] 昱君,郭江鹏,张鲁,等.奶牛代谢紊乱与褪黑素应用研究进展[J].中国乳业,2019(4):71-75. YU J,GUO J P,ZHANG L,et al.Progress in metabolic disorders and application of melatonin in dairy cows[J].China Dairy,2019(4):71-75.(in Chinese)
[15] BERNABUCCI U,BIFFANI S,BUGGIOTTI L,et al.The effects of heat stress in Italian Holstein dairy cattle[J].Journal of Dairy Science,2014,97(1):471-486.  
[16] 薛白,王之盛,李胜利,等.温湿度指数与奶牛生产性能的关系[J].中国畜牧兽医,2010,37(3):153-157. XUE B,WANG Z S,LI S L,et al.Relationship between temperature and humidity index and cow performance[J].China Animal Husbandry & Veterinary Medicine,2010,37(3):153-157.(in Chinese)
[17] 张志登,敬盈嘉,刘影,等.热应激对泌乳奶牛生理指标及生产性能的影响[J].中国畜牧杂志,2020,56(4):169-172. ZHANG Z D,JING Y J,LIU Y,et al.Effects of heat stress on physiological indexes and performance of lactating dairy cows[J].Chinese Journal of Animal Science,2020,56(4):169-172.(in Chinese)
[18] LECCHI C,ROTA N,VITALI A,et al.In vitro assessment of the effects of temperature on phagocytosis,reactive oxygen species production and apoptosis in bovine polymorphonuclear cells[J].Veterinary Immunology and Immunopathology,2016,182:89-94.
[19] YANG M H,SHI J M,TIAN J H,et al.Exogenous melatonin reduces somatic cell count of milk in Holstein cows[J].Scientific Reports,2017,7:43280.
[20] 史建民.褪黑素降低牛奶体细胞数和提高奶牛繁殖性能的研究与应用[D].博士学位论文.北京:中国农业大学,2015. SHI J M.Study and application of melatonin in reducing somatic cell count and improving reproductive performance of dairy cows[D].Ph.D.Thesis.Beijing:China Agricultural University,2015.(in Chinese)
[21] ABDELNABY E A,AMAL M,ABO EL-MAATY.Melatonin and CIDR improved the follicular and luteal hemodynamics,uterine and ovarian arteries vascular perfusion,ovarian hormones,and nitric oxide in cyclic cows[J/OL].Reproduction in Domestic Animals,2020-10-22].https://doi.org/10.1111/rda.13888.
[22] GARCIA-ISPIERTO I,ABDELFATAH A,LÓPEZ-GATIUS F.Melatonin treatment at dry-off improves reproductive performance postpartum in high-producing dairy cows under heat stress conditions[J].Reproduction in Domestic Animals,2013,48(4):577-583.  
[23] 贺亮,徐乾琨,贺峻琳,等.褪黑激素对动物生产性能作用研究进展[J].湖南农业科学,2016(8):117-119. HE L,XU Q K,HE J L,et al.Advance in effects of melatonin on animal production[J].Hunan Agriculture Sciences,2016(8):117-119. (in Chinese)
[24] 仉连平,张月周,李福云,等.热应激对奶牛的影响及其缓解措施[J].中国草食动物科学,2019,39(4):58-61. JI L P,ZHANG Y Z,LI F Y,et al.The effect of heat stress on dairy cows and its mitigation measures[J].China Herbivore Science,2019,39(4):58-61.(in Chinese)
[25] AULDIST M J,TURNER S A,MCMAHON C D,et al.Effects of melatonin on the yield and composition of milk from grazing dairy cows in New Zealand[J].Journal of Dairy Research,2007,74(1):52-57.  
[26] 姚松阳,刘国世.褪黑素与奶牛牛乳体细胞数防控研究进展[J].中国乳业,2019(5):39-42. YAO S Y,LIU G S.Progress in research on melatonin and prevention and control of cow milk somatic cell count[J].China Dairy,2019(5):39-42.(in Chinese)
[27] RAKIB M R H,ZHOU M,XU S,et al.Effect of heat stress on udder health of dairy cows[J].Journal of Dairy Research,2020,87(3):315-321.  
[28] TESTA F,MARANO G,AMBROGI F,et al.Study of the association of atmospheric temperature and relative humidity with bulk tank milk somatic cell count in dairy herds using generalized additive mixed models[J].Research in Veterinary Science,2017,114:511-517.
[29] MARAI I F M,HAEEB A A M.Buffalo's biological functions as affected by heat stress-a review[J].Livestock Science,2010,127(2/3):89-109.
[30] VALE W G.Effects of environment on buffalo reproduction[J].Italian Journal of Animal Science,2007,6(Suppl.2):130-142.
[31] PERERA B M A O.Reproductive cycles of buffalo[J].Animal Reproduction Science,2011,124(3/4):194-199.
[32] MEGAHED G,ANWAR M,WASFY S,et al.Influence of heat stress on the cortisol and oxidant-antioxidants balance during oestrous phase in buffalo-cows (Bubalus bubalis):thermo-protective role of antioxidant treatment[J].Reproduction in Domestic Animals,2008,43(6):672-677.  
[33] RAMADAN T A,SHARMA R K,PHULIA S,et al.Manipulation of reproductive performance of lactating buffaloes using melatonin and controlled internal drug release device treatment during out-of-breeding season under tropical conditions[J].Theriogenology,2016,86(4):1048-1053.  
[34] RAMADAN T A,KUMAR D,GHUMAN S S,et al.Melatonin-improved buffalo semen quality during non-breeding season under tropical condition[J].Domestic Animal Endocrinology,2019,68:119-125.
[35] DASH S,CHAKRAVARTY A K,SAH V,et al.Influence of temperature and humidity on pregnancy rate of Murrah buffaloes under subtropical climate[J].Asian-Australasian Journal of Animal Sciences,2015,28(7):943-950.  
[36] 郭振伟,黄永军,范威宏,等.褪黑素对水牛卵母细胞体外成熟的影响及其受体介导机制的探究[J].畜牧兽医学报,2019,50(2):314-322. GUO Z W,HUANG Y J,FAN W H,et al.Effect of melatonin on in vitro maturation of buffalo oocytes and its receptor mediated mechanism[J].Chinese Journal of Animal and Veterinary Sciences,2019,50(2):314-322.(in Chinese)
[37] KAVITA,PHOGAT J B,PANDEY A K,et al.Effects of melatonin supplementation prior to ovsynch protocol on ovarian activity and conception rates in anestrous Murrah buffalo heifers during out of breeding season[J].Reproductive Biology,2018,18(2):161-168.  
[38] 高翔.褪黑素对青年母牛同期排卵定时输精效果的影响[D].硕士学位论文.长春:吉林农业大学,2019. GAO X.The effects of melatonin on synchronization ovulation and artificial insemination on heifers[D].Master's Thesis.Changchun:Jilin Agricultural University,2019.(in Chinese)
[39] 佟桂芝,宋斌,王洪宝,等.褪黑素对牛体外胚胎生产效果的影响[J].现代畜牧科技,2017(12):1-2. TONG G Z,SONG B,WANG H B,et al.Effect of melatonin on bovine embryo production in vitro[J].Modern Animal Husbandry Science & Technology,2017(12):1-2.(in Chinese)
[40] KUMAR A,MEHROTRA S,SINGH G,et al.Sustained delivery of exogenous melatonin influences biomarkers of oxidative stress and total antioxidant capacity in summer-stressed anestrous water buffalo (Bubalus bubalis)[J].Theriogenology,2015,83(9):1402-1407.  
[41] 李梓芃.水牛奶中体细胞变化规律和夏季应用褪黑素对奶中体细胞数及同期发情的作用[D].硕士学位论文.武汉:华中农业大学,2018. LI Z P.Changes of somatic cells in buffalo and effect of melatonin on somatic cell count and estrus synchronization in milk in summer[D].Master's Thesis.Wuhan:Huazhong Agricultural University,2018.(in Chinese)
[42] D'OCCHIO M J,GHUMAN S P,NEGLIA G,et al.Exogenous and endogenous factors in seasonality of reproduction in buffalo:a review[J].Theriogenology,2020,150:186-192.
[43] DE CASTRO CAVALLARI F,LEAL CL L V,ZVI R,et al.Effects of melatonin on production of reactive oxygen species and developmental competence of bovine oocytes exposed to heat shock and oxidative stress during in vitro maturation[J].Zygote,2019,27(4):262.
[44] SAKATANI M,YAMANAKA K,BALBOULA A Z,et al.Heat stress during in vitro fertilization decreases fertilization success by disrupting anti-polyspermy systems of the oocytes[J].Molecular Reproduction and Development,2015,82(1):36-47.  
[45] LI Y,ZHANG Z Z,HE C J,et al.Melatonin protects porcine oocyte in vitro maturation from heat stress[J].Journal of Pineal Research,2015,59(3)365-375.
[46] 张振南,陈丹朔,任立坤,等.褪黑素提高热应激猪卵母细胞的质量[J].黑龙江畜牧兽医,2015(23):7-9,13. ZHANG Z N,CHEN D S,REN L K,et al.Melatonin improves the quality of porcine oocytes exposed to heat stress[J].Heilongjiang Animal Science and Veterinary Medicine,2015(23):7-9,13.(in Chinese)
[47] 边小娜,张家新.褪黑激素抗氧化作用的研究进展[J].安徽农学通报,2017,23(9):24-27. BIAN X N,ZHANG J X.Research progress on the antioxidant effect of melatonin[J].Anhui Agricultural Science Bulletin,2017,23(9):24-27.(in Chinese)
[48] 蒋旭琴,韩志君,梅晓冬.褪黑素对免疫系统的调节作用及其应用研究进展[J].细胞与分子免疫学杂志,2007,23(11):1091-1093. JIANG X Q,HAN Z J,MEI X D.Research progress on melatonin regulation and application of immune system[J].Chinese Journal of Cellular and Molecular Immunology,2007,23(11):1091-1093.(in Chinese)
[49] GALANO A,TAN D X,REITER R J.Melatonin as a natural ally against oxidative stress:a physicochemical examination[J].Journal of Pineal Research,2011,51(1):1-16.  
[50] 贾甜甜,文扬,高蕾蕾,等.内质网应激对哺乳动物卵母细胞成熟的影响研究进展[J].动物医学进展,2020,41(4):110-114. JIA T T,WEN Y,GAO L L,et al.Research progress of endoplasmic reticulum stress on mammalian oocyte maturation[J].Progress in Veterinary Medicine,2020,41(4):110-114.(in Chinese)
[51] REITER R J.Melatonin reduces oxidant damage and promotes mitochondrial respiration[J].Annals of the New York Academy of Sciences,2002,959(1):238-250.  
[52] SU J M,WANG Y S,XING X P,et al.Melatonin significantly improves the developmental competence of bovine somatic cell nuclear transfer embryos[J].Journal of Pineal Research,2015,59(4):455-468.  
[53] BARROS V R P,MONTE A P O,SANTOS J M S,et al.Effects of melatonin on the in vitro growth of early antral follicles and maturation of ovine oocytes[J].Domestic Animal Endocrinology,2020,71:106386.
[54] TANABE M,TAMURA H,TAKETANI T,et al.Melatonin protects the integrity of granulosa cells by reducing oxidative stress in nuclei,mitochondria,and plasma membranes in mice[J].Journal of Reproduction and Development,2015,61(1):35-41.  
[55] FU Y,HE C J,JI P Y,et al.Effects of melatonin on the proliferation and apoptosis of sheep granulosa cells under thermal stress[J].International Journal of Molecular Sciences,2014,15(11):21090-21104.  
[56] PAPIS K,POLESZCZUK O,WENTA-MUCHALSKA E,et al.Melatonin effect on bovine embryo development in vitro in relation to oxygen concentration[J].Journal of Pineal Research,2007,43(4):321-326.  
[57] ALEMU T W,PANDEY H O,WONDIM D S,et al.Oxidative and endoplasmic reticulum stress defense mechanisms of bovine granulosa cells exposed to heat stress[J].Theriogenology,2018,110:130-141.
[58] LI J Y,GAO H,TIAN Z,et al.Effects of chronic heat stress on granulosa cell apoptosis and follicular atresia in mouse ovary[J].Journal of Animal Science and Biotechnology,2016,7:57.
[59] BRODSKY J L,CHIOSIS G.Hsp70 molecular chaperones:emerging roles in human disease and identification of small molecule modulators[J].Current Topics in Medicinal Chemistry,2006,6(11):1215-1225.  
[60] HASSAN F,NAWAZ A,REHMAN M S,et al.Prospects of HSP70 as a genetic marker for thermo-tolerance and immuno-modulation in animals under climate change scenario[J].Animal Nutrition,2019,5(4):340-350.  
[61] WANG J Z,SUI H S,MIAO D Q,et al.Effects of heat stress during in vitro maturation on cytoplasmic versus nuclear components of mouse oocytes[J].Reproduction,2009,137(2):181-189.  
[62] PARK H J,PARK J Y,KIM J W,et al.Melatonin improves the meiotic maturation of porcine oocytes by reducing endoplasmic reticulum stress during in vitro maturation[J].Journal of Pineal Research,2018,64(2):e12458.
Outlines

/