[1] 刘美霞,戚进,余伯阳.党参药理作用研究进展[J].海峡药学,2018,30(11):36-39. LIU M X,QI J,YU B Y.Research progress on the pharmacological activity of codonopsis pilosula[J].Strait Pharmaceutical Journal,2018,30(11):36-39.(in Chinese)
[2] GAO S M,LIU J S,WANG M,et al.Traditional uses,phytochemistry,pharmacology and toxicology of
Codonopsis:a review[J].Journal of Ethnopharmacology,2018,219:50-70.
[3] 褚旭,刘晓菊,邱敬满,等.党参多糖对细颗粒物所致慢性阻塞性肺疾病小鼠肺泡巨噬细胞吞噬功能障碍加剧的抑制作用[J].中华医学杂志,2016(14):1134-1138. CHU X,LIU X J,QIU J M,et al.Inhibitory effects of
Codonopsis pilosula polysaccharides on the deterioration of impaired phagocytosis of alveolar macrophage induced by fine particulate matter in chronic obstructive pulmonary disease mice[J].National Medical Journal of China,2016,96(14):1134-1138. (in Chinese)
[4] HE J Y,MA N,ZHU S,et al.The genus
Codonopsis (Campanulaceae):a review of phytochemistry,bioactivity and quality control[J].Journal of Natural Medicines,2015,69(1):1-21.

[5] YANG C X,GOU Y Q,CHEN J Y,et al.Structural characterization and antitumor activity of a pectic polysaccharide from
Codonopsis pilosula[J].Carbohydrate Polymers,2013,98(1):886-895.

[6] SUN Y X.Immunological adjuvant effect of a water-soluble polysaccharide,CPP,from the roots of
Codonopsis pilosula on the immune responses to ovalbumin in mice[J].Chemistry & Biodiversity,2009,6(6):890-896.

[7] JING Y P,LI A P,LIU Z R,et al.Absorption of
Codonopsis pilosula saponins by coexisting polysaccharides alleviates gut microbial dysbiosis with dextran sulfate sodium-induced colitis in model mice[J].BioMed Research International,2018,2018:1781036.
[8] 尹莉莉.党参多糖对仔猪免疫机能的影响[D].硕士学位论文.合肥:安徽农业大学,2016. YIN L L.Effects of
Codonopsis pilosula polysaccharide on immune function in piglets[D].Master's Thesis.Hefei:Anhui Agricultural University,2016. (in Chinese)
[9] 张雅君,梁忠岩,赵伟,等.党参水溶性多糖的分离、纯化及组成分析[J].中国药学杂志,2005,40(14):1107-1109. ZHANG Y J,LIANG Z Y,ZHAO W,et al.Separation,purification and compositional analysis of water soluble polysaccharide CPPS3 from
Codonpsis pilosula[J].Chinese Pharmaceutical Journal,2005,40(14):1107-1109. (in Chinese)
[10] SUN Y X,LIU J C,KENNEDY J F.Application of response surface methodology for optimization of polysaccharides production parameters from the roots of
Codonopsis pilosula by a central composite design[J].Carbohydrate Polymers,2010,80(3):949-953.

[11] 李达,何先元,冯婧,等.党参多糖水提法工艺研究[J].安徽农业科学,2011,39(30):18514-18515. LI D,HE X Y,FENG J,et al.Study on water extraction technology of
Codonopsis pilosula polysaccharide[J].Journal of Anhui Agricultural Sciences,2011,39(30):18514-18515. (in Chinese)
[12] 武新亮,王宏军,白子霞,等.响应面法优化川党参多糖的提取工艺研究[J].天津中医药,2015,32(7):432-436. WU X L,WANG H J,BAI Z X,et al.Optimization of the extraction technique of
Codonopsis tangshen Dliv. polysaccharide using response surface methodoloy[J].Tianjin Journal of Traditional Chinese Medicine,2015,32(7):432-436. (in Chinese)
[13] 高建德,朱晓玉,宋开蓉,等.复合酶辅助提取党参中多糖工艺的优化[J].中成药,2018,40(5):1189-1193. GAO J D,ZHU X Y,SONG K R,et al.Optimization of complex enzyme assisted extraction of polysaccharides from
Codonopsis pilosula[J].Chinese Traditional Patent Medicine,2018,40(5):1189-1193. (in Chinese)
[14] 周大寨,朱玉昌,黄卫,等.复合酶法提取板党多糖的研究[J].时珍国医国药,2009,20(8):1928-1929. ZHOU D Z,ZHU Y C,HUANG W,et al.Study on the extraction of platinum-party polysaccharides by complex enzymatic method[J].Lishizhen Medicine and Materia Medica Research,2009,20(8):1928-1929. (in Chinese)
[15] 余兰,陈华,娄方明.微波辅助萃取洛龙党参多糖的工艺优化[J].食品研究与开发,2011,32(9):26-29. YU L,CHEN H,LOU F M.Optimizing technics of extracting polysaccharides from
Codonopsis tangshen Oliv with miicrowave-assisted extraction[J].Food Research and Development,2011,32(9):26-29. (in Chinese)
[16] ZOU Y F,CHEN X F,YANG W Y,et al.Response surface methodology for optimization of the ultrasonic extraction of polysaccharides from
Codonopsis pilosula Nannf.var.
modesta L.T.Shen[J].Carbohydrate Polymers,2011,84(1):503-508.

[17] 张锐,张旭,刘建群,等.党参的亚临界水提取工艺优选[J].中国实验方剂学杂志,2013,19(10):34-37. ZHANG R,ZHANG X,LIU J Q,et al.Optimization of subcritical water extraction technology of
Codonopsis tangshen[J].Chinese Journal of Experimental Traditional Medical Formulae,2013,19(10):34-37. (in Chinese)
[18] 梁欢,黄进,王丽,等.药用植物硒多糖的研究进展[J].中国中药杂志,2018,43(15):3080-3092. LIANG H,HUANG J,WANG L,et al.Recent research progress of selenium polysaccharides from medicinal plants[J].China Journal of Chinese Materia Medica,2018,43(15):3080-3092. (in Chinese)
[19] 金黎明,刘李娜,许永斌,等.硒化党参多糖的制备及其抗氧化性能研究[J].大连民族学院学报,2014,16(1):10-13,38. JIN L M,LIU L N,XU Y B,et al.Research on synthesis and antioxidant activity of selenium-
Codonopsis pilosula polysaccharide[J].Journal of Dalian Nationalities University,2014,16(1):10-13,38. (in Chinese)
[20] QIN T,REN Z,LIN D D,et al.Effects of selenizing
Codonopsis pilosula polysaccharide on macrophage modulatory activities[J].Journal of Microbiology and Biotechnology,2016,26(8):1358-1366.

[21] QIN T,REN Z,LIU X P,et al.Study of the selenizing
Codonopsis pilosula polysaccharides protects RAW264.7 cells from hydrogen peroxide-induced injury[J].International Journal of Biological Macromolecules,2018,125:534-543.
[22] ZHAO X N,HU Y L,WANG D Y,et al.The comparison of immune-enhancing activity of sulfated polysaccharidses from
Tremella and
Condonpsis pilosula[J].Carbohydrate Polymers,2013,98(1):439-443.
[23] WANG Z J,XIE J H,SHEN M Y,et al.Sulfated modification of polysaccharides:synthesis,characterization and bioactivities[J].Trends in Food Science & Technology,2018,74:147-157.
[24] LIU F,GENG C,QU Y K,et al.The feeding of dietary
Codonopsis pilosula polysaccharide enhances the immune responses,the expression of immune-related genes and the growth performance of red swamp crayfish (
Procambarus clarkii)[J].Fish & Shellfish Immunology,2020,103:321-331.
[25] LIU C,CHEN J,LI E T,et al.The comparison of antioxidative and hepatoprotective activities of
Codonopsis pilosula polysaccharide (CP) and sulfated CP[J].International Immunopharmacology,2015,24(2):299-305.

[26] 王希春,朱电锋,尹莉莉,等.党参多糖对仔猪生长性能、血清细胞因子及肠黏膜分泌型免疫球蛋白A含量的影响[J].动物营养学报,2017,29(11):4069-4075. WANG X C,ZHU D F,YIN L L,et al.Effects of
Codonopsis pilosula polysaccharide on growth performance,serum cytokines and intestinal mucosal secretory immunoglobulin A contents of piglets[J].Chinese Journal of Animal Nutrition,2017,29(11):4069-4075. (in Chinese)
[27] LAN R X,PARK J W,LEE D W,et al.Effects of
Astragalus membranaceus,
Codonopsis pilosula and allicin mixture on growth performance,nutrient digestibility,faecal microbial shedding,immune response and meat quality in finishing pigs[J].Journal of Animal Physiology and Animal Nutrition,2017,101(6):1122-1129.

[28] 李开菊,陈文倩,周霞,等.素花党参多糖对乌鸡生长性能、免疫功能、血常规及肠道菌群的影响[J].四川畜牧兽医,2017,44(10):32-34,36. LI K J,CHEN W Q,ZHOU X,et al.Effects of
Codonopsis pilosula polysaccharides on the production performance,immune function,routine blood indexes and intestinal microflora of black-bone chicken[J].Sichuan Animal and Veterinary Sciences,2017,44(10):32-34,36. (in Chinese)
[29] 刘文生.党参多糖、皂甙提取及对小鼠抗氧化和免疫功能影响的研究[D].硕士学位论文.晋中:山西农业大学,2004. LIU W S.Study on extraction of
Codonopsis polysaccharide saponins and its effects on antioxidant and immune function in mice[D].Master's Thesis.Jinzhong:Shanxi Agricultural University,2004. (in Chinese)
[30] 李启艳,祝清芬,刘春霖,等.党参多糖分离纯化及抗氧化活性研究[J].中草药,2017,48(5):907-912. LI Q Y,ZHU Q F,LIU C L,et al.Isolation and purification of
Codonopsis pilosula polysaccharide and its anti-oxidant activity[J].Chinese Traditional and Herbal Drugs,2017,48(5):907-912. (in Chinese)
[31] 孙嘉琪.硫酸化党参多糖对巨噬细胞及小鼠急性氧化损伤的保护作用[D].硕士学位论文.广州:华南农业大学,2018. SUN J Q.Protective effect of sulfated
Codonopsis pilosula polysaccharide on oxidative injury in macrophages and mice[D].Master's Thesis.Guangzhou:Huanan Agricultural University,2018. (in Chinese)
[32] FU Y P,BIN F,ZHU Z K,et al.The polysaccharides from
Codonopsis pilosula modulates the immunity and intestinal microbiota of cyclophosphamide-treated immunosuppressed mice[J].Molecules,2018,23(7):1801
[33] 石轶男,杨绒娟,扆妍妍,等.党参多糖可溶性粉对肉仔鸡血清ND抗体水平、IgG及肠道SIgA含量的影响[J].中国兽药杂志,2016,50(9):47-52. SHI Y N,YANG R J,YI Y Y,et al.Effects of
Codonopsis pilosula polysaccharides soluble powder on broiler serum antibody level of ND,IgG and intestinal SIgA content[J].Chinese Journal of Veterinary Drug,2016,50(9):47-52. (in Chinese)
[34] 阎辉,毛湘冰,余冰,等.基于生猪疾病模型探讨营养对免疫的调控作用[J].动物营养学报,2020,32(10):4471-4479. YAN H,MAO X B,YU B,et al.Nutritional regulation on immunity based on pig disease model[J].Chinese Journal of Animal Nutrition,2020,32(10),4471-4479. (in Chinese)
[35] ZHANG P,HU L H,BAI R B,et al.Structural characterization of a pectic polysaccharide from
Codonopsis pilosula and its immunomodulatory activities
in vivo and
in vitro[J].International Journal of Biological Macromolecules,2017,104:1359-1369.
[36] LIU F Y,ZHANG X F,LING P X,et al.Immunomodulatory effects of xanthan gum in LPS-stimulated RAW 264.7 macrophages[J].Carbohydrate Polymers,2017,169:65-74.
[37] 孟燕,徐玉洁,张宝徽,等.党参多糖不同组分的抗炎活性及机制研究[J].中国房,2020,31(11):1348-1352. MENG Y,XU Y J,ZHANG B H,et al.Study on the anti-inflammatory activity and mechanism of different components from
Codonopsis radix polysaccharides[J].China Pharmacy,2020,31(11):1348-1352. (in Chinese)
[38] GAO Z Z,ZHANG C,JING L R,et al.The structural characterization and immune modulation activitives comparison of
Codonopsis pilosula polysaccharide (CPPS) and selenizing CPPS (sCPPS) on mouse
in vitro and
in vivo[J].International Journal of Biological Macromolecules,2020,160:814-822.
[39] SUN Y X,LIU J C.Structural characterization of a water-soluble polysaccharide from the roots of
Codonopsis pilosula and its immunity activity[J].International Journal of Biological Macromolecules,2008,43(3):279-282.

[40] DENG X L,FU Y J,LUO S,et al.Polysaccharide from radix
Codonopsis has beneficial effects on the maintenance of T-cell balance in mice[J].Biomedicine & Pharmacotherapy,2019,112:108682.
[41] 林丹丹,秦韬,任喆,等.硒化党参多糖对免疫抑制小鼠免疫功能的影响[J].中国畜牧兽医,2016,43(6):1544-1549. LIN D D,QIN T,REN Z,et al.Effects of selenium-
Codonopsis pilosula polysaccharide on immune function of immunosuppressed mice[J].China Animal Husbandry and Veterinary Medicine,2016,43(6):1544-1549. (in Chinese)
[42] LI J K,ZHANG X,CAO L Y,et al.Three inulin-type fructans from
Codonopsis pilosula (Franch.) Nannf. roots and their prebiotic activity on
Bifidobacterium longum[J].Molecules,2018,23(13):3123.
[43] 马方励,沈雪梅,时军.党参多糖对实验动物胃肠道功能的影响[J].安徽医药,2014,18(9):1626-1629,1630. MA F L,SHEN X M,SHI J.Effect of
Codonopsis polysaccharide on gastrointestinal tract of experimental rats and mice[J].Anhui Medical and Pharmaceutical Journal,2014,18(9):1626-1629,1630. (in Chinese)
[44] 周卫东,项磊,卢汉琪,等.党参多糖改善5-氟尿嘧啶诱导小肠黏膜炎的实验研究[J].辽宁中医杂志,2016,43(7):1495-1498. ZHOU W D,XIANG L,LU H Q,et al.Radix
Codonopsi polysaccharide against 5-fluorouracil-induced gastrointestinal mucositis in mice model[J].Liaoning Journal of Traditional Chinese Medicine,2016,43(7):1495-1498. (in Chinese)
[45] 周建强,潘琦,王涛,等.党参多糖对免疫雏鸡抗体效价和淋巴细胞增殖的影响[J].江苏农业科学,2010(3):263-264. ZHOU J Q,PAN Q,WANG T,et al.Effects of
Codonopsis pilosula polysaccharide on antibody titer and lymphocyte proliferation in chickens[J].Jiangsu Agricultural Sciences,2010(3):263-264. (in Chinese)
[46] 韩天飞,袁娜娜,张洪宇,等.党参多糖和黄芪多糖对鸡球虫疫苗免疫增强作用的研究[J].黑龙江畜牧兽医,2018(11):172-175. HAN T F,YUAN N N,ZHANG H Y,et al.Study on the immune enhancement effect of
Codonopsis pilosula polysaccharides and astragalus polysaccharides on chicken coccidiosis vaccine[J].Heilongjiang Animal Science and Veterinary Medicine,2018(11):172-175. (in Chinese)
[47] 李恺,盛瑜,於廉沁,等.中药提取物对兔出血症疫苗免疫效果的影响[J].中国养兔,2017(6):7-9. LI K,SHENG Y,YU L Q,et al.The effect of Chinese herb extracts on rabbit hemorrhagic disease (RHD) vaccine[J].Chinese Journal of Rabbit Farming,2017(6):7-9. (in Chinese)
[48] LIU C,CHEN J,LI E T,et al.Solomonseal polysaccharide and sulfated
Codonopsis pilosula polysaccharide synergistically resist newcastle disease virus[J].PLoS One,2015,10(2):0117916.
[49] XU C,LIU Y,YUAN G X,et al.The contribution of side chains to antitumor activity of a polysaccharide from
Codonopsis pilosula[J].International Journal of Biological Macromolecules,2012,50(4):891-894.