Research Progress on Effects of Exogenous Bile Acids on Heat Stress in Livestock and Poultry

  • YIN Chang ,
  • WU Weida ,
  • CAO Aizhi ,
  • ZHANG Hongfu
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  • 1. State Key Laboratory of Animal Nutrition, Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing 100193, China;
    2. Shandong Longchang Animal Health Care Co., Ltd., Jin'an 251100, China

Received date: 2020-11-21

  Online published: 2021-06-10

Abstract

As an important component of bile, bile acid plays an important role in promoting nutrient absorption and protecting the health of livestock and poultry. It combines emulsified lipids with polar phospholipid molecules through a non-receptor-mediated pathway to promote the absorption of lipids and fat-soluble substances. It also acts as a key signal molecule to activate specific receptors and cell signaling pathways to not only promote glucose and lipid metabolism, but also protect against the intestine barrier dysfunction and oxidative stress. In recent years, the roles of exogenous bile acids on alleviating the negative states of heat stress, such as insulin resistance, fat accumulation, intestinal barrier dysfunction, and oxidative stress, have gradually attracted attention. This article systematically described the metabolism of bile acids, summarized in detail the regulation mechanism of bile acids on the body, and provided references for the theoretical research and application of exogenous bile acids to relieve heat stress in growing pigs and broilers.

Cite this article

YIN Chang , WU Weida , CAO Aizhi , ZHANG Hongfu . Research Progress on Effects of Exogenous Bile Acids on Heat Stress in Livestock and Poultry[J]. Chinese Journal of Animal Nutrition, 2021 , 33(6) : 3081 -3090 . DOI: 10.3969/j.issn.1006-267x.2021.06.010

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