SWINE NUTRITION AND FEED

Effects of Lactobacillus casei Strain Shirota on Growth Performance, Antioxidant Function and Bioamines in Colon of Weaned Piglets

  • RAO Zebin ,
  • ZENG Yan ,
  • LIU Yubo ,
  • HU Ping ,
  • HU Hong ,
  • TANG Zhiru
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  • 1. Laboratory for Animal Nutrition and Bio-Feed, College of Animal Science and Technology, Southwest University, Chongqing 400715, China;
    2. Hunan Institute of Microbiology, Changsha 410000, China

Received date: 2020-11-21

  Online published: 2021-06-10

Abstract

This experiment was conducted to investigate the effects of Lactobacillus casei strain Shirota on growth performance, antioxidant function and bioamines in colon of weaned piglets. Thirty healthy 28-day-old Duroc×Landrace×Yorkshire weaned piglets were randomly divided into 3 groups with 10 replicates per group and 1 pig per replicate. Piglets in the control group were fed a basal diet, those in the antibiotic group were fed the basal diet+100 mg/kg colistin sulfate, and those in the Lactobacillus casei group were fed the basal diet+5×109 CFU Lactobacillus casei strain Shirota embedded with agar block for oral administration every day. The pre-experiment lasted for 4 days, and the experimental period lasted for 28 days. The results showed as follows:1) compared with the control group, the final weight, average daily gain and average daily feed intake of weaned piglets in the Lactobacillus casei group were significantly increased (P<0.05), the total antioxidant capacity and the activity of total superoxide dismutase, nitric oxide synthase (NOS) and glutathione peroxidase in plasma were extremely significantly increased (P<0.01), the NOS activity in liver was extremely significantly increased (P<0.01), the number of goblet cells in jejunum was significantly increased (P<0.05), the activity of glutamic oxalacetic transaminase (GOT) and glutamic-pyruvic transaminase in plasma was extremely significantly decreased (P<0.01), the GOT activity in liver was significantly increased (P<0.05), and the contents of tryptamine, methylamine, histamine, cadaverine and putrescine in colon were extremely significantly decreased (P<0.01). 2) Compared with the antibiotic group, the GOT activity in plasma of weaned piglets in the Lactobacillus casei group was significantly increased (P<0.05), the activity of catalase and NOS in both plasma and liver was extremely significantly increased (P<0.01), the number of goblet cells in jejunum was significantly increased (P<0.05), and the histamine content in colon was extremely significantly decreased (P<0.01). In conclusion, dietary Lactobacillus casei strain Shirota can improve the growth performance and antioxidant function of weaned piglets, reduce the bioamine contents in colon, and has the effect of replacing antibiotics.

Cite this article

RAO Zebin , ZENG Yan , LIU Yubo , HU Ping , HU Hong , TANG Zhiru . Effects of Lactobacillus casei Strain Shirota on Growth Performance, Antioxidant Function and Bioamines in Colon of Weaned Piglets[J]. Chinese Journal of Animal Nutrition, 2021 , 33(6) : 3165 -3175 . DOI: 10.3969/j.issn.1006-267x.2021.06.019

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