[1] 肖世泽.高温刺激对LPS诱导奶牛乳腺上皮细胞炎症的作用与机制的初步研究[D].硕士学位论文.武汉:华中农业大学,2020. XIAO S Z.The effect and mechanism of high temperature stimulation on LPS induced inflammation of bovine mammary epithelial cells[D].Ph.D.Thesis.Wuhan:Huazhong Agricultural University,2020.(in Chinese)
[2] SALMAN S,DINSE D,KHOL-PARISINI A,et al.Colostrum and milk selenium,antioxidative capacity and immune status of dairy cows fed sodium selenite or selenium yeast[J].Archives of Animal Nutrition,2013,67(1):48-61.

[3] ZHANG B Q,GUO Y M,YAN S M,et al.The protective effect of selenium on the lipopolysaccharide-induced oxidative stress and depressed gene expression related to milk protein synthesis in bovine mammary epithelial cells[J].Biological Trace Element Research,2020,197(1):141-148.

[4] GONG J,NI L L,WANG D F,et al.Effect of dietary organic selenium on milk selenium concentration and antioxidant and immune status in midlactation dairy cows[J].Livestock Science,2014,170:84-90.
[5] SORDILLO L M.Selenium-dependent regulation of oxidative stress and immunity in periparturient dairy cattle[J].Veterinary Medicine International,2013,2013:154045.
[6] CALABRESE V,CORNELIUS C,LESO V,et al.Oxidative stress,glutathione status,sirtuin and cellular stress response in type 2 diabetes[J].Biochimica et Biophysica Acta:Molecular Basis of Disease,2011,1822(5):729-736.
[7] SORDILLO L M,MAVANGIRA V.The nexus between nutrient metabolism,oxidative stress and inflammation in transition cows[J].Animal Production Science,2014,54(54):1204-1214.
[8] GUO Y M,GONG J,ZHENG Y G,et al.Protection of bovine mammary epithelial cells from hydrogen peroxide-induced oxidative cell damage by selenium[J].Czech Journal of Animal Science,2018,63(3):94-102.

[9] MAVANGIRA V,SORDILLO L M.Role of lipid mediators in the regulation of oxidative stress and inflammatory responses in dairy cattle[J].Research in Veterinary Science,2017,116:4-14.
[10] SCHMIDT H H W,WALTER U.NO at work[J].Cell,1994,78(6):919-925.

[11] BECKMAN J S,BECKMAN T W,CHEN J,et al.Apparent hydroxyl radical production by peroxynitrite:implications for endothelial injury from nitric oxide and superoxide[J].Proceedings of the National Academy of Sciences of the United States of America,1990,87(4):1620-1624.

[12] PRYOR W A,SQUADRITO G L.The chemistry of peroxynitrite:α product from the reaction of nitric oxide with superoxide[J].American Journal of Physiology:Lung Cellular and Molecular Physiology,1995,268(5):L699-L722.
[13] GUO Y M,GUO X Y,YAN S M,et al.Mechanism underlying the protective effect of selenium on NO-induced oxidative damage in bovine mammary epithelial cells[J].Biological Trace Element Research,2019,191(1):104-114.

[14] ATAKISI O,ORAL H,ATAKISI E,et al.Subclinical mastitis causes alterations in nitric oxide,total oxidant and antioxidant capacity in cow milk[J].Research in Veterinary Science,2010,89(1):10-13.

[15] 弓剑.硒对奶牛乳腺抗氧化功能的影响及其机理研究[D].博士学位论文.呼和浩特:内蒙古农业大学,2014. GONG J.The effect and underling mechanism of selenium on antioxidative function of mammary gland in dairy cows[D].Ph.D.Thesis.Hohhot:Inner Mongolia Agricultural University,2014.(in Chinese)
[16] SUN X,JIA H,XU Q,et al.Lycopene alleviates H
2O
2-induced oxidative stress, inflammation and apoptosis in bovine mammary epithelial cells via the NFE2L2 signaling pathway[J].Food & Function,2019,10(10):6276-6285.

[17] BURTON J L,ERSKINE R J.Immunity and mastitis Some new ideas for an old disease[J].Veterinary Clinics of North America.Food Animal Practice,2003,19(1):1-45.

[18] BAE H,JEONG C H,CHENG W N,et al.Oxidative stress-induced inflammatory responses and effects of N-acetylcysteine in bovine mammary alveolar cells[J].Journal of Dairy Research,2017,84(4):418-425.

[19] DIEZ-FRAILE A,MEYER E,DUCHATEAU L,et al.Effect of proinflammatory mediators and glucocorticoids on L-selectin expression in peripheral blood neutrophils from dairy cows in various stages of lactation[J].American Journal of Veterinary Research,2004,65(10):1421-1426.

[20] SORDILLO L M.Nutritional strategies to optimize dairy cattle immunity[J].Journal of Dairy Science,2016,99(6):4967-4982.

[21] SPEARS J W,WEISS W P.Role of antioxidants and trace elements in health and immunity of transition dairy cows[J].Veterinary Journal,2008,176(1):70-76.

[22] CEBALLOS-MARQUEZ A,BARKEMA H W,STRYHN H,et al.The effect of selenium supplementation before calving on early-lactation udder health in pastured dairy heifers[J].Journal of Dairy Science,2010,93(10):4602-4612.

[23] WARKEN A C,LOPES L S,BOTTARI N B,et al.Mineral supplementation stimulates the immune system and antioxidant responses of dairy cows and reduces somatic cell counts in milk[J].Anais da Academia Brasileira de Ciências,2018,90(2):1649-1658.

[24] SUN L L,WANG F,WU Z H,et al.Comparison of selenium source in preventing oxidative stress in bovine mammary epithelial cells[J].Animals,2020,10(5):842.
[25] WEISS W P.Selenium nutrition of dairy cows:comparing responses to organic and inorganic selenium forms[C]//LYONS T P,JAQUES K A.Proceeding of the 19th Alltech Annual Symposium Nutrition,Biotechnology Feed Food.England:Nottingham University Press,2003:333-373.
[26] RUIZ S,PERGOLA P E,ZAGER R A,et al.Targeting the transcription factor Nrf2 to ameliorate oxidative stress and inflammation in chronic kidney disease[J].Kidney International,2013,83(6):1029-1041.

[27] GESSNER D K,SCHLEGEL G,RINGSEIS R,et al.Up-regulation of endoplasmic reticulum stress induced genes of the unfolded protein response in the liver of periparturient dairy cows[J].BMC Veterinary Research,2014,10(1):46.
[28] CULLINAN S B,DIEHL J A.Coordination of ER and oxidative stress signaling:the PERK/Nrf2 signaling pathway[J].International Journal of Biochemistry and Cell Biology,2006,38(3):317-332.

[29] PARK E Y,CHO I J,KIM S G.Transactivation of the PPAR-responsive enhancer module in chemopreventive glutathione S-transferase gene by the peroxisome proliferator-activated receptor-γ and retinoid X receptor heterodimer[J].Cancer Research,2004,64(10):3701-3713.

[30] 苏芮.硒通过Nrf2/GPX1-PPARγ-NF-κB信号通路对一氧化氮诱导的奶牛乳腺上皮细胞氧化应激的减缓作用[D].硕士学位论文.呼和浩特:内蒙古农业大学,2019. SU R.The mechanism on Se alleviating oxidative stress in the bovine mammary epithelial cells induced by NO through Nrf2/GPx1-PPARγ-NF-κB signaling pathway[D].Master's Thesis.Hohhot:Inner Mongolia Agricultural University,2019.(in Chinese)
[31] SIOMEK A.NF-κB signaling pathway and free radical impact[J].Acta Biochimica Polonica,2012,59(3):323-331.
[32] 石惠宇.维生素A通过Nrf2/谷胱甘肽过氧化物酶1/NF-κB信号通路缓解奶牛乳腺上皮细胞氧化应激的机理研究[D].博士学位论文.呼和浩特:内蒙古农业大学,2018. SHI H Y.The mechanism on VA alleviating oxidative stress in the bovine mammary epithelial cells by Nrf2/glutathione peroxidase1/NF-κB signaling pathway[D].Ph.D.Thesis.Hohhot:Inner Mongolia Agricultural University,2018.(in Chinese)
[33] PAN M H,HONG H M,LIN C L,et al.Se-methylselenocysteine inhibits lipopolysaccharide-induced NF-κB activation and iNOS induction in RAW 264.7 murine macrophages[J].Molecular Nutrition & Food Research,2011,55(5):723-732.

[34] ZHENG Y G,YAN S M,QI J Y,et al.Protective effect of chitosan oligosaccharide against oxidative damage of peripheral blood mononuclear cells in dairy cows induced by diethylenetriamine/nitric oxide via NF-κB signalling pathway[J].Italian Journal of Animal Science,2020,19(1):602-609.

[35] 郑亚光.壳聚糖通过NF-κB信号通路调节奶牛抗氧化功能与抗炎症反应的机理研究[D].博士学位论文.呼和浩特:内蒙古农业大学,2020. ZHENG Y G.Mechanism of chitosan regulating antioxidant function and anti-inflammatory response of dairy cows by NF-κB signaling pathway[D].Ph.D.Thesis.Hohhot:Inner Mongolia Agricultural University,2020.(in Chinese)
[36] WENK J,SCHVLLER J,HINRICHS C,et al.Overexpression of phospholipid-hydroperoxide glutathione peroxidase in human dermal fibroblasts abrogates UVA irradiation-induced expression of interstitial collagenase/matrix metalloproteinase-1 by suppression of phosphatidylcholine hydroperoxide-mediated NFκB activation and interleukin-6 release[J].Journal of Biological Chemistry,2004,279(44):45634-45642.

[37] HOLMSTRÖM K M,FINKEL T.Cellular mechanisms and physiological consequences of redox-dependent signalling[J].Nature Reviews Molecular Cell Biology,2014,15(6):411-421.

[38] 郭咏梅,张博綦,闫素梅,等.硒对脂多糖诱导的奶牛乳腺上皮细胞氧化损伤的保护作用[J].动物营养学报,2017,29(9):3375-3384. GUO Y M,ZHANG B Q,YAN S M,et al.Protective effect of selenium on bovine mammary epithelial cells oxidative damaged by lipopolysaccharide[J].Chinese Journal of Animal Nutrition,2017,29(9):3375-3384.(in Chinese)
[39] 郭咏梅.硒通过TrxR1/MAPK信号通路缓解奶牛乳腺上皮细胞氧化应激的机理研究[D].博士学位论文.呼和浩特:内蒙古农业大学,2020. GUO Y M.Mechanism of selenium attenuating oxidative stress in bovine mammary epithelial cells through modulation of thioredoxin reductase 1/MAPK signalling pathway[D].Ph.D.Thesis.Hohhot:Inner Mongolia Agricultural University,2020.(in Chinese)
[40] WANG K,ZHANG J,WANG X L,et al.Thioredoxin reductase was nitrated in the aging heart after myocardial ischemia/reperfusion[J].Rejuvenation Research,2013,16(5):377-385.

[41] TRIGONA W L,MULLARKY I K,CAO Y Z,et al.Thioredoxin reductase regulates the induction of haem oxygenase-1 expression in aortic endothelial cells[J].Biochemical Journal,2006,394(1):207-216.

[42] CHANG L F,KARIN M.Mammalian MAP kinase signalling cascades[J].Nature,2001,410(6824):37-40.

[43] AL-GAYYAR M M H,ABDELSAID M A,MATRAGOON S,et al.Thioredoxin interacting protein is a novel mediator of retinal inflammation and neurotoxicity[J].British Journal of Pharmacology,2011,164(1):170-180.

[44] BERNABUCCI U,RONCHI B,LACETERA N,et al.Influence of body condition score on relationships between metabolic status and oxidative stress in periparturient dairy cows[J].Journal of Dairy Science,2005,88(6):2017-2026.

[45] 毕崇亮.硒对金黄色葡萄球菌诱导的巨噬细胞和奶牛乳腺上皮细胞炎性损伤的保护作用研究[D].博士学位论文.扬州:扬州大学,2016. BI C L.The protective effect and molecular mechanisms of selenium against inflammation injury of primary bovine mammary epithelial cells and macrophages induced by
Staphylococcus aureus[D].Master's Thesis.Yangzhou:Yangzhou University,2016.(in Chinese)
[46] WEI C.The role of 15-lipoxygenase-1- and cyclooxygenase-2-derived lipid mediators in endothelial cell proliferation[D].Ph.D.Thesis.Philadelphia:University of Pennsylvania,2010.
[47] GUO Y M,YAN S M,GONG J,et al.The protective effect of selenium on bovine mammary epithelial cell injury caused by depression of thioredoxin reductase[J].Biological Trace Element Research,2017,184(1):75-82.
[48] ASTUDILLO A M,BALGOMA D,BALBOA D A,et al.Dynamics of arachidonic acid mobilization by inflammatory cells[J].Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids,2012,1821(2):249-256.
[49] 任善茂,陶勇,李春梅.硒对母牛免疫功能及健康的改善作用研究进展[J].畜牧与兽医,2015,47(2):123-126. REN S M,TAO Y,LI C M.Research progress of selenium on improving immune function and health of cows[J].Animal Husbandry and Veterinary Medicine,2015,47(2):123-126.(in Chinese)
[50] STRAIF D,WERZ O,KELLNER R,et al.Glutathione peroxidase-1 but not -4 is involved in the regulation of cellular 5-lipoxygenase activity in monocytic cells[J].Biochemical Journal,2000,349(2):455-461.

[51] CONRAD M,SANDIN A,FORSTER H,et al.12/15-lipoxygenase-derived lipid peroxides control receptor tyrosine kinase signaling through oxidation of protein tyrosine phosphatases[J].Proceedings of the National Academy of Sciences of the United States of America,2010,107(36):15774-15779.