SWINE NUTRITION AND FEED

Effects of Bacillus subtilis on Growth Performance of Weaned Pglets: a Meta-Analysis

  • YANG Kuanmin ,
  • SHEN Yuanhang ,
  • WANG Li ,
  • JIANG Zongyong
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  • 1. Guangdong Key Laboratory of Animal Breeding and Nutrition, Guangdong Laboratory for Lingnan Modern Agriculture, Maoming Branch, State Key Laboratory of Livestock and Poultry Breeding, Key Laboratory of Animal Nutrition and Feed Science in South China Ministry of Agriculture and Rural Affairs, Institute of Animal Science, Guangdong Academy of Agricultural Sciences, Guangzhou 510640, China;
    2. Shenzhen Premix Nutrition Co., Ltd., Shenzhen 518103, China

Received date: 2021-01-26

  Online published: 2021-08-11

Supported by

 

Abstract

The aim of this systematic review and Meta-analysis was to explore the effects of Bacillus subtilis on the growth performance of weaned piglets. The study conducted a literature search about randomized controlled trials on the effects of Bacillus subtilis on the growth performance of weaned piglets in English and Chinese databases, including CNKI, CQVIP, Wan Fang Data, Science Direct and Web of science databases. The retrieval period was from the establishment of the database to 2020. According to the inclusion and exclusion criteria, we formulated, the literatures were screened and the data were extracted. The Meta-analysis was conducted using Review Manager V5.3 software. Publication bias analysis, subgroup analysis and sensitivity analysis were also performed. A total of 1 742 samples were included in 18 studies. The results of Meta-analysis showed that average daily gain of Bacillus subtilis group was significantly higher than that of control group[P<0.000 01, standardized mean difference (SMD)=1.34, 95% confidence interval (CI):0.76 to 1.93]. Meanwhile, feed to gain ratio of Bacillus subtilis group was significantly lower than that of control group (P=0.000 3, SMD=-0.86, 95% CI:-1.33 to -0.40). Moreover, lower diarrhea rate was found in Bacillus subtilis group than control group (P=0.000 2, SMD=-3.07, 95% CI:-4.68 to -1.46), but there was no significant difference in feed intake between the two groups (P=0.12, SMD=0.33,95% CI:-0.08 to 0.74). This study demonstrates that Bacillus subtilis improves the average daily gain of weaned piglets, reduces the feed to gain ratio and diarrhea rate, and doesn't influence the average daily feed intake. The above results provide a theoretical basis for the selection of additives in the production of weaned piglets.

Cite this article

YANG Kuanmin , SHEN Yuanhang , WANG Li , JIANG Zongyong . Effects of Bacillus subtilis on Growth Performance of Weaned Pglets: a Meta-Analysis[J]. Chinese Journal of Animal Nutrition, 2021 , 33(8) : 4332 -4341 . DOI: 10.3969/j.issn.1006-267x.2021.08.014

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