RUMINANT AND HERBIVORE NUTRITION AND FEED

Effects of Sanguinarine on Performance, Antioxidation and Immune Function of Dairy Goats

  • LING Hao ,
  • XIAO Hongyan ,
  • ZHANG Ziyang ,
  • HE Youkuan ,
  • QU Jingtao ,
  • ZHANG Peihua
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  • 1. College of Animal Science and Technology, Hunan Agricultural University, Changsha 410128, China;
    2. Chengbu Shanmu Animal Husbandry Co., Ltd., Shaoyang 422500, China

Received date: 2021-01-26

  Online published: 2021-08-11

Supported by

 

Abstract

The purpose of this experiment was to study the effects of sanguinarine on performance, antioxidation and immune function of dairy goats. Twenty-four Xinong Sanen dairy goats with similar parity, lactation age, milk yield and body weight were randomly divided into 2 groups with 12 goats in each group. Goats in the control group were fed a total mixed ration, and others in the sanguinarine group were fed the total mixed ration+400 mg/kg sanguinarine. The pre-feeding period was 10 days and the trial period was 42 days. The results showed as follows:1) the milk yield of the sanguinarine group was significantly higher than that of the control group (P<0.05). There were no significant differences in dry matter intake and feed conversion rate between the two groups (P<0.05). 2) The serum malondialdehyde content of the sanguinarine group was significantly lower than that of the control group (P<0.01), and the serum glutathione peroxidase activity and total antioxidant capacity were significantly higher than those of the control group (P<0.01). There was no significant difference in serum superoxide dismutase activity between the two groups (P<0.05). 3) The blood white blood cell number of the sanguinarine group was significantly higher than that of the control group (P<0.05), and the blood neutrophil number was significantly higher than that of the control group (P<0.01). There were no significant differences in other blood cell indexes between the two groups (P<0.05). 4) The contents of interleukin-2 and immunoglobulin G in serum of the sanguinarine group were significantly higher than that of the control group (P<0.05), and the contents of interleukin-4 and immunoglobulin A in serum were significantly higher than those of the control group (P<0.01). There were no significant differences in other serum immune indexes between the two groups (P<0.05). To sum up, under the conditions of this experiment, adding sanguinarine to the diet can increase the milk yield of dairy goats, and improve the body antioxidant and immune function.

Cite this article

LING Hao , XIAO Hongyan , ZHANG Ziyang , HE Youkuan , QU Jingtao , ZHANG Peihua . Effects of Sanguinarine on Performance, Antioxidation and Immune Function of Dairy Goats[J]. Chinese Journal of Animal Nutrition, 2021 , 33(8) : 4541 -4548 . DOI: 10.3969/j.issn.1006-267x.2021.08.034

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