SPECIAL ECONOMIC ANIMAL NUTRITION AND FEED

Effects of L-Carnosine on Growth and Healthy of Canis lupus familiaris

  • CHEN Xuewei ,
  • LI Yang ,
  • QIN Shunyi ,
  • YANG Hua ,
  • ZHANG Jianbin
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  • Tianjin Key Laboratory of Agricultural Animal Breeding and Healthy Husbandry, College of Animal Science and Veterinary Medicine, Tianjin Agricultural University, Tianjin 300384, China

Received date: 2021-01-18

  Online published: 2021-08-11

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Abstract

This experiment was conducted to investigate the effects of L-carnosine on growth performance, serum biochemical indexes and antioxidant capacity of Canis lupus familiaris. Twenty-four 3-month-old Canis lupus familiaris were randomly divided into 4 groups with 6 dogs per group. The dogs in control group (group C) was fed a basic diet, and those in the groups Ⅰ, Ⅱ and Ⅲ were fed the basic diet with 300, 600 and 900 mg/kg L-carnosine, respectively. The preliminary test lasted for 7 d and the formal test lasted for 28 d. At the end of the experiment, sensory evaluation was performed and indicators related to growth performance, serum biochemical indexes, immunologic function and antioxidant capacity were measured. The results showed as follows:1) the average daily gain and average daily feed intake of dogs were inversely proportional to the additive amount of L-carnosine. With the increase of L-carnosine additive amount, the sensory scores of dogs increased gradually, and the scores in group Ⅲ were significantly higher than those in other groups (P<0.05). 2) For the fecal score, mean scores in group Ⅱ most closely matched the optimal fecal score; with the increase of L-carnosine additive amount, the apparent digestibility of crude fat was increased, the apparent digestibilities of crude protein and crude fiber in groups Ⅱ and Ⅲ were significantly higher than those in group C (P<0.05). 3) Serum cholesterol (CHO) content in experimental groups was significantly lower than that in group C (P<0.05); the activity of glutamic-oxalacetic transaminase (AST) in serum in group Ⅰwas significantly higher than that in group C (P<0.05); the contents of immunoglobulin A (IgA) and immunoglobulin G (IgG) in serum in group Ⅱ were significantly higher than those in groups C and Ⅰ (P<0.05); the content of malondialdehyde (MDA) in serum in group Ⅲ was significantly lower than that in group C (P<0.05), and the content of serum creatinine (CRE) in group Ⅲ was significantly lower than that in group C (P<0.05). However, the total antioxidant capacity (T-AOC), the activities of glutathione peroxidase (GSH-Px) and superoxide dismutase (SOD) in serum were significantly higher than those in group C (P<0.05). In summary, dietary L-carnosine can improve the sensory score of canine, increase digestion, absorption and metabolism ability, reduce the content of total cholesterol in serum, improve the body immunity and antioxidant capacity; dietary suitable L-carnosine supplemental level is 600 mg/kg.

Cite this article

CHEN Xuewei , LI Yang , QIN Shunyi , YANG Hua , ZHANG Jianbin . Effects of L-Carnosine on Growth and Healthy of Canis lupus familiaris[J]. Chinese Journal of Animal Nutrition, 2021 , 33(8) : 4604 -4614 . DOI: 10.3969/j.issn.1006-267x.2021.08.040

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