[1] CHATURVEDI P,BHAT R A H,PANDE A.Antimicrobial peptides of fish:innocuous alternatives to antibiotics[J].Reviews in Aquaculture,2020,12(1):85-106.
[2] PATEL S,AKHTAR N.Antimicrobial peptides (AMPs):the quintessential ‘offense and defense’ molecules are more than antimicrobials[J].Biomedicine & Pharmacotherapy,2017,95:1276-1283.
[3] 王鑫,张萌萌,姜宁,等.宿主防御肽调节动物肠道屏障功能的研究进展[J].动物营养学报,2018,30(9):3410-3416. WANG X,ZHANG M M,JIANG N,et al.Research progress in regulation of animal intestinal barrier function by host defense peptides[J].Chinese Journal of Animal Nutrition,2018,30(9):3410-3416.(in Chinese)
[4] 齐志涛,徐杨,邹钧,等.水产动物抗菌肽研究进展[J].水产学报,2020,44(9):1572-1583. QI Z T,XU Y,ZOU J,et al.Review of antimicrobial peptides from aquatic animals[J].Journal of Fisheries of China,2020,44(9):1572-1583.(in Chinese)
[5] VALERO Y,SARAIVA-FRAGA M,COSTAS B,et al.Antimicrobial peptides from fish:beyond the fight against pathogens[J].Reviews in Aquaculture,2020,12(1):224-253.
[6] RAJU S V,SARKAR P,KUMAR P,et al.Piscidin,fish antimicrobial peptide:structure, classification,properties,mechanism,gene regulation and therapeutical importance[J].International Journal of Peptide Research and Therapeutics,2021,27(1):91-107.
[7] ZHUANG Z R,YANG X D,HUANG X Z,et al.Three new piscidins from orange-spotted grouper (
Epinephelus coioides):phylogeny, expression and functional characterization[J].Fish & Shellfish Immunology,2017,66:240-253.
[8] CETUK H,MARAMBA J,BRITT M,et al.Differential interactions of piscidins with phospholipids and lipopolysaccharides at membrane interfaces[J].Langmuir,2020,36(18):5065-5077.
[9] MIHAILESCU M,SORCI M,SECKUTE J,et al.Structure and function in antimicrobial piscidins:histidine position, directionality of membrane insertion,and pH-dependent permeabilization[J].Journal of the American Chemical Society,2019,141(25):9837-9853.
[10] TALANDASHTI R,MAHDIUNI H,JAFARI M,et al.Molecular basis for membrane selectivity of antimicrobial peptide pleurocidin in the presence of different eukaryotic and prokaryotic model membranes[J].Journal of Chemical Information and Modeling,2019,59(7):3262-3276.
[11] HSU W H,LAI Y J,WU S C.Effects of the anti-microbial peptide pardaxin plus sodium erythorbate dissolved in different gels on the quality of Pacific white shrimp under refrigerated storage[J].Food Control,2017,73:712-719.
[12] CIPOLARI O C,DE OLIVEIRA NETO X A,CONCEIÇÃO K.Fish bioactive peptides:a systematic review focused on sting and skin[J].Aquaculture,2020,515:734598.
[13] PAN C Y,LIN C N,CHIOU M T,et al.The antimicrobial peptide pardaxin exerts potent anti-tumor activity against canine perianal gland adenoma[J]. Oncotarget,2015,6(4):2290-2301.
[14] 尹航.非溶酶体途径脂质体用于干细胞转染和肿瘤细胞基因编辑的研究[D].硕士学位论文.苏州:苏州大学,2019. YIN H.Non-lysosomal pathway liposomes for stem cell transfection and gene editing in cancer cells[D].Master's Thesis.Suzhou:Suzhou University,2019.(in Chinese)
[15] 马萍.鲈鱼、石斑鱼、豹鳎鱼、泥鳅和臭蛙抗菌肽在毕赤酵母SMD1168中的高效表达[D].硕士学位论文.兰州:兰州交通大学,2018. MA P.High-level expression in
Pichia pastoris SMD1168 of moronecidin,epinecidin-1,pardaxin-4,misgurin and smelly frog antibacterial peptide[D].Master's Thesis.Lanzhou:Lanzhou Jiaotong University,2018.(in Chinese)
[16] BROWNE M J,FENG C Y,BOOTH V,et al.Characterization and expression studies of gaduscidin-1 and gaduscidin-2;paralogous antimicrobial peptide-like transcripts from Atlantic cod (
Gadus morhua)[J].Developmental & Comparative Immunology,2011,35(3):399-408.
[17] SANDHU G,BOOTH V,MORROW M R.Role of charge in lipid vesicle binding and vesicle surface saturation by gaduscidin-1 and gaduscidin-2[J].Langmuir,2020,36(33):9867-9877.
[18] PAN C Y,CHEN J Y,CHENG Y S E,et al.Gene expression and localization of the epinecidin-1 antimicrobial peptide in the grouper (
Epinephelus coioides),and its role in protecting fish against pathogenic infection[J].DNA and Cell Biology,2007,26(6):403-413.
[19] SU B C,WU T H,HSU C H,et al.Distribution of positively charged amino acid residues in antimicrobial peptide epinecidin-1 is crucial for
in vitro glioblastoma cytotoxicity and its underlying mechanisms[J].Chemico-Biological Interactions,2020,315:108904.
[20] MASON A J,BERTANI P,MOULAY G,et al.Membrane interaction of chrysophsin-1,a histidine-rich antimicrobial peptide from red sea bream[J].Biochemistry,2007,46(51):15175-15187.
[21] ALEXANDER T E,SMITH I M,LIPSKY Z W,et al.Role of lipopolysaccharides and lipoteichoic acids on C-chrysophsin-1 interactions with model Gram-positive and Gram-negative bacterial membranes[J].Biointerphases,2020,15(3):031007.
[22] LAUTH X,SHIKE H,BURNS J C,et al.Discovery and characterization of two isoforms of moronecidin, a novel antimicrobial peptide from hybrid striped bass[J].The Journal of Biological Chemistry,2002,277(7):5030-5039.
[23] CAMPAGNA S,SAINT N,MOLLE G,et al.Structure and mechanism of action of the antimicrobial peptide piscidin[J].Biochemistry,2007,46(7):1771-1778.
[24] SILPHADUANG U,NOGA E J.Peptide antibiotics in mast cells of fish[J].Nature,2001,414(6861):268-269.
[25] NOGA E J,SILPHADUANG U,PARK N G,et al.Piscidin 4,a novel member of the piscidin family of antimicrobial peptides[J].Comparative Biochemistry and Physiology Part B:Biochemistry and Molecular Biology,2009,152(4):299-305.
[26] SALGER S A,CASSADY K R,READING B J,et al.A diverse family of host-defense peptides (piscidins) exhibit specialized anti-bacterial and anti-protozoal activities in fishes[J].PLoS One,2016,11(8):e0159423.
[27] SALERNO G,PARRINELLO N,ROCH P,et al.cDNA sequence and tissue expression of an antimicrobial peptide, dicentracin; a new component of the moronecidin family isolated from head kidney leukocytes of sea bass,
Dicentrarchus labrax[J].Comparative Biochemistry and Physiology Part B:Biochemistry and Molecular Biology,2007,146(4):521-529.
[28] COLE A M,WEIS P,DIAMOND G.Isolation and characterization of pleurocidin,an antimicrobial peptide in the skin secretions of winter flounder[J].The Journal of Biological Chemistry,1997,272(18):12008-12013.
[29] DOUGLAS S E,PATRZYKAT A,PYTYCK J,et al.Identification, structure and differential expression of novel pleurocidins clustered on the genome of the winter flounder,
Pseudopleuronectes americanus (Walbaum)[J].European Journal of Biochemistry,2003,270(18):3720-3730.
[30] DOUGLAS S E,GALLANT J W,GONG Z,et al.Cloning and developmental expression of a family of pleurocidin-like antimicrobial peptides from winter flounder,
Pleuronectes americanus (Walbaum)[J].Developmental & Comparative Immunology,2001,25(2):137-147.
[31] SUGIYAMA N,ARAKI M,ISHIDA M,et al.Further isolation and characterization of grammistins from the skin secretion of the soapfish
Grammistes sexlineatus[J].Toxicon,2005,45(5):595-601.
[32] KAJI T,SUGIYAMA N,ISHIZAKI S,et al.Molecular cloning of grammistins, peptide toxins from the soapfish
Pogonoperca punctata,by hemolytic screening of a cDNA library[J].Peptides,2006,27(12):3069-3076.
[33] SAITOH T,SETO Y,FUJIKAWA Y,et al.Distribution of three isoforms of antimicrobial peptide, chrysophsin-1,-2 and -3,in the red sea bream,
Pagrus (
Chrysophrys)
major[J].Analytical Biochemistry,2019,566:13-15.
[34] SCHEENSTRA M R,VAN HARTEN R M,VELDHUIZEN E J A,et al.Cathelicidins modulate TLR-activation and inflammation[J].Frontiers in Immunology,2020,11:1137.
[35] BRIDLE A,NOSWORTHY E,POLINSKI M,et al.Evidence of an antimicrobial-immunomodulatory role of Atlantic salmon cathelicidins during infection with
Yersinia ruckeri[J].PLoS One,2011,6(8):e23417.
[36] TOMASINSIG L,ZANETTI M.The cathelicidins-structure,function and evolution[J].Current Protein & Peptide Science,2005,6(1):23-34.
[37] 厉政.细鳞鱼Cathelicidins的鉴定及宿主防御肽CATH_BRALE的结构与功能分析[D].硕士学位论文.大连:大连理工大学,2013. LI Z.Identification of cathelicidins, structural and functional charaterization of CATH_BRALE,the defense molecule in the ancient salmonoid,
Brachymystax lenok[D].Master's Thesis.Dalian:Dalian University of Technology,2013.(in Chinese)
[38] CONTRERAS G,SHIRDEL I,BRAUN M S,et al.Defensins:transcriptional regulation and function beyond antimicrobial activity[J].Developmental & Comparative Immunology,2020,104:103556.
[39] MA Y Q,KIM S S,MAENG C H,et al.Key role of disulfide bridges in the antimicrobial activity of beta-defensin from olive flounder[J].International Journal of Peptide Research and Therapeutics,2020,26(1):291-299.
[40] CHATURVEDI P,DHANIK M,PANDE A.Molecular characterization and
in silico analysis of defensin from
Tor putitora (Hamilton)[J].Probiotics and Antimicrobial Proteins,2015,7(3):207-215.
[41] ZHOU Y C,LEI Y,CAO Z J,et al.A β-defensin gene of
Trachinotus ovatus might be involved in the antimicrobial and antiviral immune response[J].Developmental & Comparative Immunology,2019,92:105-115.
[42] HARTE A,TIAN G M,XU Q Q,et al.Five subfamilies of β-defensin genes are present in salmonids:evolutionary insights and expression analysis in Atlantic salmon
Salmo salar[J].Developmental & Comparative Immunology,2020,104:103560.
[43] YANG K,HOU B R,REN F F,et al.Characterization of grass carp (
Ctenopharyngodon idella) beta-defensin 1:implications for its role in inflammation control[J].Bioscience, Biotechnology, and Biochemistry,2019,83(1):87-94.
[44] ZHOU Y,ZHOU Q J,QIAO Y,et al.The host defense peptide β-defensin confers protection against
Vibrio anguillarum in ayu,
Plecoglossus altivelis[J].Developmental & Comparative Immunology,2020,103:103511.
[45] LOMBARDI L,MAISETTA G,BATONI G,et al.Insights into the antimicrobial properties of hepcidins:advantages and drawbacks as potential therapeutic agents[J].Molecules,2015,20(4):6319-6341.
[46] SHIRDEL I,KALBASSI M R,HOSSEINKHANI S,et al.Cloning,characterization and tissue-specific expression of the antimicrobial peptide hepcidin from caspian trout (
Salmo caspius) and the antibacterial activity of the synthetic peptide[J].Fish & Shellfish Immunology,2019,90:288-296.
[47] LIU Y Y,HAN X D,CHEN X Z,et al.Molecular characterization and functional analysis of the hepcidin gene from roughskin sculpin (
Trachidermus fasciatus)[J].Fish & Shellfish Immunology,2017,68:349-358.
[48] XU T J,SUN Y N,SHI G,et al.Miiuy croaker hepcidin gene and comparative analyses reveal evidence for positive selection[J].PLoS One,2012,7(4):e35449.
[49] HOCQUELLET A,LE SENECHAL C,GARBAY B.Importance of the disulfide bridges in the antibacterial activity of human hepcidin[J].Peptides,2012,36(2):303-307.
[50] XIE J S,OBIEFUNA V,HODGKINSON J W,et al.Teleost antimicrobial peptide hepcidin contributes to host defense of goldfish (
Carassius auratus L.) against
Trypanosoma carassii[J].Developmental & Comparative Immunology,2019,94:11-15.
[51] MA Y Q,LEE C J,KIM S S,et al.Role of hepcidins from black rockfish (
Sebastes schlegelii) in iron-metabolic function and bacterial defense[J].Journal of Marine Science and Engineering,2020,8(7):493.
[52] JIANG Y,CHEN B,YAN Y L,et al.Hepcidin protects against iron overload-induced inhibition of bone formation in zebrafish[J].Fish Physiology and Biochemistry,2019,45(1):365-374.
[53] 费威,李慧,马龙洋,等.水生动物组蛋白衍生抗菌肽的结构特征和抗菌活性研究进展[J].河南农业科学,2015,44(4):9-13. FEI W,LI H,MA L Y,et al.Structure characteristics and antibacterial activities of histone-derived antibacterial peptides in aquatic animal[J].Journal of Henan Agricultural Sciences,2015,44(4):9-13.(in Chinese)
[54] PARSEGHIAN M H,LUHRS K A.Beyond the walls of the nucleus:the role of histones in cellular signaling and innate immunity[J].Biochemistry and Cell Biology,2006,84(4):589-604.
[55] ATHIRA P P,ANJU M V,ANOOJA V V,et al.A histone H2A-derived antimicrobial peptide, hipposin from mangrove whip ray,
Himantura walga:molecular and functional characterisation[J].3 Biotech,2020,10(11):467.
[56] UZZELL T,STOLZENBERG E D,SHINNAR A E,et al.Hagfish intestinal antimicrobial peptides are ancient cathelicidins[J].Peptides,2003,24(11):1655-1667.
[57] BROEKMAN D C,FREI D M,GYLFASON G A,et al.Cod cathelicidin:isolation of the mature peptide,cleavage site characterisation and developmental expression[J].Developmental & Comparative Immunology,2011,35(3):296-303.
[58] LU X J,CHEN J,HUANG Z A,et al.Identification and characterization of a novel cathelicidin from ayu,
Plecoglossus altivelis[J].Fish & Shellfish Immunology,2011,31(1):52-57.
[59] DONG J J,WU F,YE X,et al.β-defensin in Nile tilapia (
Oreochromis niloticus):sequence,tissue expression,and anti-bacterial activity of synthetic peptides[J].Gene,2015,566(1):23-31.
[60] WANG G L,LI J H,ZOU P F,et al.Expression pattern,promoter activity and bactericidal property of β-defensin from the mandarin fish
Siniperca chuatsi[J].Fish & Shellfish Immunology,2012,33(3):522-531.
[61] ZOU J,MERCIER C,KOUSSOUNADIS A,et al.Discovery of multiple beta-defensin like homologues in teleost fish[J].Molecular Immunology,2007,44(4):638-647.
[62] GUO M L,WEI J G,HUANG X H,et al.Antiviral effects of β-defensin derived from orange-spotted grouper (
Epinephelus coioides)[J].Fish & Shellfish Immunology,2012,32(5):828-838.
[63] CUESTA A,MESEGUER J,ESTEBAN M Á.The antimicrobial peptide hepcidin exerts an important role in the innate immunity against bacteria in the bony fish gilthead seabream[J].Molecular Immunology,2008,45(8):2333-2342.
[64] PEREIRO P,FIGUERAS A,NOVOA B.A novel hepcidin-like in turbot (
Scophthalmus maximus L.) highly expressed after pathogen challenge but not after iron overload[J].Fish & Shellfish Immunology,2012,32(5):879-889.
[65] SHIKE H,SHIMIZU C,LAUTH X,et al.Organization and expression analysis of the zebrafish hepcidin gene,an antimicrobial peptide gene conserved among vertebrates[J].Developmental & Comparative Immunology,2004,28(7/8):747-754.
[66] LAUTH X,BABON J J,STANNARD J A,et al.Bass hepcidin synthesis,solution structure,antimicrobial activities and synergism,and
in vivo hepatic response to bacterial infections[J].Journal of Biological Chemistry,2005,280(10):9272-9282.
[67] PELLE G D,PERÀ G,BELARDINELLI M C,et al.Trematocine,a novel antimicrobial peptide from the antarctic fish
Trematomus bernacchii:identification and biological activity[J].Antibiotics,2020,9(2):66.
[68] CHEN Y,WU J,CHENG H L,et al.Anti-infective effects of a fish-derived antimicrobial peptide against drug-resistant bacteria and its synergistic effects with antibiotic[J].Frontiers in Microbiology,2020,11:602412.
[69] SHAN Z G,YANG Y P,GUAN N,et al.NKL-24:a novel antimicrobial peptide derived from zebrafish NK-lysin that inhibits bacterial growth and enhances resistance against
Vibrio parahaemolyticus infection in Yesso scallop,
Patinopecten yessoensis[J].Fish & Shellfish Immunology,2020,106:431-440.
[70] YANG S,DONG Y T,AWEYA J J,et al.A hemoglobin-derived antimicrobial peptide,LCH4,from the large yellow croaker (
Larimichthys crocea) with potential use as a food preservative[J].LWT,2020,131:09656.
[71] TAHERI B,MOHAMMADI M,NABIPOUR I,et al.Identification of novel antimicrobial peptide from Asian sea bass (
Lates calcarifer) by
in silico and activity characterization[J].PLoS One,2018,13(10):e0206578.
[72] JIANG M L,YANG X Q,WU H M,et al.An active domain HF-18 derived from hagfish intestinal peptide effectively inhibited drug-resistant bacteria
in vitro/vivo[J].Biochemical Pharmacology,2020,172:113746.
[73] LI T T,LIU Q W,CHEN H T,et al.Antibacterial activity and mechanism of the cell-penetrating peptide CF-14 on the gram-negative bacteria,
Escherichia coli[J].Fish & Shellfish Immunology,2020,100:489-495.
[74] KAWASAKI H,IWAMURO S.Potential roles of histones in host defense as antimicrobial agents[J].Infectious Disorders-Drug Targets,2008,8(3):195-205.
[75] WEN L L,ZHAO M L,CHI H,et al.Histones and chymotrypsin-like elastases play significant roles in the antimicrobial activity of tongue sole neutrophil extracellular traps[J].Fish & Shellfish Immunology,2018,72:470-476.
[76] HE S W,WANG G H,YUE B,et al.TO17:a teleost antimicrobial peptide that induces degradation of bacterial nucleic acids and inhibits bacterial infection in red drum,
Sciaenops ocellatus[J].Fish & Shellfish Immunology,2018,72:639-645.
[77] ZHOU J G,WEI J G,XU D,et al.Molecular cloning and characterization of two novel hepcidins from orange-spotted grouper,
Epinephelus coioides[J].Fish & Shellfish Immunology,2011,30(2):559-568.
[78] 黄小建,李跃龙,戚南山,等.抗菌肽的生物学活性及其在畜禽生产中的作用[J].动物医学进展,2020,41(12):115-119. HUANG X J,LI Y L,QI N S,et al.Biological activity of antimicrobial peptides and their roles in livestock and poultry production[J].2020,41(12):115-119.(in Chinese)
[79] YUAN C H,MA Y L,SHIH P C,et al.The antimicrobial peptide tilapia piscidin 3 induces mitochondria-modulated intrinsic apoptosis of osteosarcoma cells[J].Biochemical Pharmacology,2020,178:114064.
[80] KUO H M,TSENG C C,CHEN N F,et al.MSP-4,an antimicrobial peptide, induces apoptosis via activation of extrinsic Fas/FasL- and intrinsic mitochondria-mediated pathways in one osteosarcoma cell line[J].Marine Drugs,2018,16(1):8.
[81] TING C H,LIU Y C,LYU P C,et al.Nile tilapia derived antimicrobial peptide TP4 exerts antineoplastic activity through microtubule disruption[J].Marine Drugs,2018,16(12):462.
[82] CHENG M H,PAN C Y,CHEN N F,et al.Piscidin-1 induces apoptosis via mitochondrial reactive oxygen species-regulated mitochondrial dysfunction in human osteosarcoma cells[J].Scientific Reports,2020,10:5045.
[83] UMASUTHAN N,MOTHISHRI M S,THULASITHA W S,et al.Molecular,genomic,and expressional delineation of a piscidin from rock bream (
Oplegnathus fasciatus) with evidence for the potent antimicrobial activities of Of-Pis1 peptide[J].Fish & Shellfish Immunology,2016,48:154-168.
[84] RUANGSRI J,SALGER S A,CAIPANG C M A,et al.Differential expression and biological activity of two piscidin paralogues and a novel splice variant in Atlantic cod (
Gadus morhua L.)[J].Fish & Shellfish Immunology,2012,32(3):396-406.
[85] 王雪洋,韩淑敏,李金库,等.抗菌肽在畜禽生产中的应用进展[J].畜牧与饲料科学,2019,40(8):35-37. WANG X Y,HAN S M,LI J K,et al.Research progress on application of antibacterial peptides in livestock and poultry production[J].2019,40(8):35-37.(in Chinese)
[86] WANG J H,LU J,ZHANG Y X,et al.Metagenomic analysis of antibiotic resistance genes in coastal industrial mariculture systems[J].Bioresource Technology,2018,253:235-243.
[87] PAN C Y,TSAI T Y,SU B C,et al.Study of the antimicrobial activity of tilapia piscidin 3(TP3) and TP4 and their effects on immune functions in hybrid tilapia (
Oreochromis spp.)[J].PLoS One,2017,12(1):e0169678.
[88] ACOSTA J,CARPIO Y,VALDÉS I,et al.Co-administration of tilapia alpha-helical antimicrobial peptides with subunit antigens boost immunogenicity in mice and tilapia (
Oreochromis niloticus)[J].Vaccine,2014,32(2):223-229.
[89] LIU S P,CHUANG S C,YANG C D.Protective immunity against
Vibrio harveyi in Grouper induced by single vaccination with poly (lactide-co-glycolide) microparticles releasing pleurocidin peptide and recombinant glyceraldehyde-3-phosphate dehydrogenase[J].Vaccines,2020,8(1):33.
[90] NGO D H,KIM S K.Marine bioactive peptides as potential antioxidants[J].Current Protein & Peptide Science,2013,14(3):189-198.
