FAN Xiangyu , ZHANG Fuqun , HUANG Tailai , CAO Manhu . Effects of Curcumin on Growth Performance, Abdominal Fat Deposition, Antioxidant Capacity, Liver Enzyme Activities and Gene Expression Related to Lipid Metabolism of Medium Speed Yellow-Feathered Broilers[J]. Chinese Journal of Animal Nutrition, 2021 , 33(10) : 5581 -5590 . DOI: 10.3969/j.issn.1006-267x.2021.10.018

[1] GUPTA S C, SUNG B, KIM J H, et al.Multitargeting by turmeric, the golden spice:from kitchen to clinic[J].Molecular Nutrition & Food Research, 2013, 57(9):1510-1528.  
[2] 狄建彬, 顾振纶, 赵笑东, 等.姜黄素的抗氧化和抗炎作用研究进展[J].中草药, 2010, 41(5):854-857. DI J B, GU Z L, ZHAO X D, et al.Advances in studies on antioxidant and anti-inflammation of curcumin[J].Chinese Traditional and Herbal Drugs, 2010, 41(5):854-857.(in Chinese)
[3] 钱兆全, 周金星.姜黄素对肉鸡日增重、料重比及肉质指标的影响[J].安徽科技学院学报, 2018, 32(6):40-43. QIAN Z Q, ZHOU J X.Effect of curcumin on daily gain, feed-to-weight ratio and meat quality index of broilers[J].Journal of Anhui Science and Technology University, 2018, 32(6):40-43.(in Chinese)
[4] NELSON K M, DAHLIN J L, BISSON J, et al.The essential medicinal chemistry of curcumin[J].Journal of Medicinal Chemistry, 2017, 60(5):1620-1637.  
[5] ILSLEY S E, MILLER H M, KAMEL C.Effects of dietary quillaja saponin and curcumin on the performance and immune status of weaned piglets[J].Journal of Animal Science, 2005, 83(1):82-88.  
[6] PANAHI Y, GHANEI M, BASHIRI S, et al.Short-term curcuminoid supplementation for chronic pulmonary complications due to sulfur mustard intoxication:positive results of a randomized double-blind placebo-controlled trial[J].Drug Research, 2015, 65(11):567-573.
[7] GAN Y X, ZHENG S C, ZHAO J Q, et al.Protein network module-based identification of key pharmacological pathways of Curcuma phaeocaulis Val. acting on hepatitis[J].Journal of Ethnopharmacology, 2018, 221:10-19.
[8] SEPTEMBRE-MALATERRE A, LE SAGE F, HATIA S, et al.Curcuma longa polyphenols improve insulin-mediated lipid accumulation and attenuate proinflammatory response of 3T3-L1 adipose cells during oxidative stress through regulation of key adipokines and antioxidant enzymes[J].BioFactors, 2016, 42(4):418-430.  
[9] HSIAO Y T, KUO C L, CHUEH F S, et al.Curcuminoids induce reactive oxygen species and autophagy to enhance apoptosis in human oral cancer cells[J].The American Journal of Chinese Medicine, 2018, 46(5):1145-1168.  
[10] HSIAO Y T, KUO C L, LIN J J, et al.Curcuminoids combined with gefitinib mediated apoptosis and autophagy of human oral cancer SAS cells in vitro and reduced tumor of SAS cell xenograft mice in vivo[J].Environmental Toxicology, 2018, 33(8):821-832.  
[11] 吴杰, 徐娇娇, 叶娟, 等.天然姜黄素类化合物抗人类呼吸道合胞病毒研究[J].中国药师, 2015(1):34-38. WU J, XU J J, YE J, et al.Study on Anti-RSV activity of natural curcuminoids[J].China Pharmacist, 2015(1):34-38.(in Chinese)
[12] 彭景华, 曹健美, 王晓柠, 等.姜黄素对内毒素脂多糖诱导的库普弗细胞分泌炎症细胞因子的抑制作用[J].中国中西医结合消化杂志, 2006(4):211-214. PENG J H, CAO J M, WANG X N, et al.Inhibiting effects of curcumin on expression of inflammatory cytokines in Kupffer cells induced by lipopolysaccharides[J].Chinese Journal of Integrated Traditional and Western Medicine on Digestion, 2006(4):211-214.(in Chinese)
[13] PATIL T N, SRINIVASAN M.Hypocholesteremic effect of curcumin in induced hypercholesteremic rats[J].Indian Journal of Experimental Biology, 1971, 9(2):167-169.
[14] 崔晓旭.姜黄素对肉鸡肝脏、肾脏及肌肉中AFB₁及其代谢物AFM₁残留及消除的影响[D].硕士学位论文.哈尔滨:东北农业大学, 2017. CUI X X.Effect of curcumin on the residual and elimination of AFB₁ and its metabolite AFM₁ in liver, kidney and muscle of broilers[D].Master's Thesis.Harbin:Northeast Agricultural University, 2017.(in Chinese)
[15] 韩刚, 崔静静, 毕瑞, 等.姜黄素、去甲氧基姜黄素和双去甲氧基姜黄素稳定性研究[J].中国中药杂志, 2008, 33(22):2611-2614. HAN G, CUI J J, BI R, et al.Study on stability of curcumine, demethoxycurcumin and bisdemethoxycurcumin[J].China Journal of Chinese Materia Medica, 2008, 33(22):2611-2614.(in Chinese)
[16] 董梅.姜黄素对肉鸡部分内脏器官和肠道生长发育的影响[J].安徽农学通报, 2014(19):86-88, 91. DONG M.Effect of curcumin on the broiler part of the internal organs and intestinal growth and development[J].Anhui Agricultural Science Bulletin, 2014(19):86-88, 91.(in Chinese)
[17] GALLI G M, GERBET R R, GRISS L G, et al.Combination of herbal components (curcumin, carvacrol, thymol, cinnamaldehyde) in broiler chicken feed:impacts on response parameters, performance, fatty acid profiles, meat quality and control of coccidia and bacteria[J].Microbial Pathogenesis, 2020, 139:103916.
[18] 胡忠泽, 王立克, 闻爱友.姜黄素对皖江黄鸡脂肪代谢的影响[J].粮食与饲料工业, 2008(4):29-30, 33. HU Z Z, WANG L K, WEN A Y.Effect of curcumin on fat metabolism in Wanjiang yellow chickens[J].Cereal & Feed Industry, 2008(4):29-30, 33.(in Chinese)
[19] 从光雷, 肖蕴祺, 张倩雲, 等.饲粮添加化香果单宁对肉鸡生长性能、屠宰性能、器官指数、肉品质、抗氧化功能和肠道发育的影响[J].动物营养学报, 2021, 33(5):2661-2671. CONG G L, XIAO Y Q, ZHANG Q Y, et al.Effects of Plotytarya strohilacea Sieb. et Zuce tannin on growth performance, slaughter performance, organ indexes, meat quality, antioxidant function and intestinal development of broilers[J].Chinese Journal of Animal Nutrition, 2021, 33(5):2661-2671.(in Chinese)
[20] RAUF A, IMRAN M, ORHAN I E, et al.Health perspectives of a bioactive compound curcumin:a review[J].Trends in Food Science & Technology, 2018, 74:33-45.
[21] 孙全友, 李文嘉, 徐彬, 等.姜黄素和地衣芽孢杆菌对肉鸡生长性能、血清抗氧化功能、肠道微生物数量和免疫器官指数的影响[J].动物营养学报, 2018, 30(8):3176-3183. SUN Q Y, LI W J, XU B, et al.Effects of curcumin and Bacillus licheniformis on growth performance, serum antioxidant function, intestinal microbe counts and immune organ indexes of broilers[J].Chinese Journal of Animal Nutrition, 2018, 30(8):3176-3183.(in Chinese)
[22] 祝国强, 侯风琴.姜黄素对肉仔鸡日增重、脂质代谢、肉品质的影响[J].饲料博览, 2007(2):49-51. ZHU G Q, HOU F Q.Effects of curcumin on daily weight gains, lipid metabolism and meat quality of broilers[J].Feed Review, 2007(2):49-51.(in Chinese)
[23] 彭翔.抗菌肽和姜黄素对肉仔鸡生长性能、抗氧化功能、肠道微生物及免疫功能的影响[D].硕士学位论文.郑州:河南农业大学, 2014. PENG X.Effects of antimicrobial peptides and curcumin on growth performance, antioxidant function, intestinal microorganism and immune function of broilers[D].Master's Thesis.Zhengzhou:Henan Agricultural University, 2014.(in Chinese)
[24] 杨泰.姜黄素对蛋鸡蛋品质、抗氧化与免疫功能及肠道形态的影响[D].硕士学术论文.长沙:湖南农业大学, 2018. YANG T.Effects of curcumin on egg quality, antioxidant and immune function and intestinal morphology[D].Master's Thesis.Changsha:Hunan Agricultural University, 2018.(in Chinese)
[25] SHAO W J, YU Z W, CHIANG Y, et al.Curcumin prevents high fat diet induced insulin resistance and obesity via attenuating lipogenesis in liver and inflammatory pathway in adipocytes[J].PLoS One, 2012, 7(1):e28784.
[26] XU Z R, HU C H, XIA M S, et al.Effects of dietary fructooligosaccharide on digestive enzyme activities, intestinal microflora and morphology of male broilers[J].Poultry Science, 2003, 82(6):1030-1036.  
[27] RAJPUT N, MUHAMMAD N, YAN R, et al.Effect of dietary supplementation of curcumin on growth performance, intestinal morphology and nutrients utilization of broiler chicks[J].The Journal of Poultry Science, 2013, 50(1):44-52.  
[28] 胡忠泽, 闻爱友, 王立克, 等.姜黄素对肉鸡腹脂沉积的影响及作用机理探讨[J].饲料博览, 2009(10):23-25. HU Z Z, WEN A Y, WANG L K, et al.Effect of curcumin on abdominal fat deposition and mechanism for broilers[J].Feed Review, 2009(10):23-25.(in Chinese)
[29] AMMON H P, WAHL M A.Pharmacology of Curcuma longa[J].Planta Medica, 1991, 57(1):1-7.  
[30] 李婉雁, 陈国开, 庞木生, 等.姜黄粉对岭南黄鸡生产性能、免疫器官指数和抗氧化能力的影响[J].仲恺农业工程学院学报, 2010, 23(3):36-39. LI W Y, CHEN G K, PANG M S, et al.Effect of turmeric powder on performance, immune organ index and anti-oxidative ability in Lingnan yellow broiler[J].Journal of Zhongkai University of Agriculture and Technology, 2010, 23(3):36-39.(in Chinese)
[31] 胡忠泽, 李敏娜, 胡元庆.姜黄素对肉鸡体内抗氧化酶活性及NO含量的影响[J].饲料研究, 2012(8):10-12. HU Z Z, LI M N, HU Y Q.Effects of curcumin on antioxidant enzyme activity and NO content in broilers[J].Feed Research, 2012(8):10-12.(in Chinese)
[32] NM J, JOSEPH A, MALIAKEL B, et al.Dietary addition of a standardized extract of turmeric (TurmaFEED^TM) improves growth performance and carcass quality of broilers[J].Journal of Animal Science and Technology, 2018, 60:8.
[33] PARASKEUAS V, FEGEROS K, PALAMIDI I, et al.Growth performance, nutrient digestibility, antioxidant capacity, blood biochemical biomarkers and cytokines expression in broiler chickens fed different phytogenic levels[J].Animal Nutrition, 2017, 3(2):114-120.  
[34] XIE Z, SHEN G, WANG Y, et al.Curcumin supplementation regulates lipid metabolism in broiler chickens[J].Poultry Science, 2019, 98(1):422-429.  
[35] SMITH S, WITKOWSKI A, JOSHI A K.Structural and functional organization of the animal fatty acid synthase[J].Progress in Lipid Research, 2003, 42(4):289-317.  
[36] PANDEY N R, RENWICK J, MISQUITH A, et al.Linoleic acid-enriched phospholipids act through peroxisome proliferator-activated receptors alpha to stimulate hepatic apolipoprotein A-I secretion[J].Biochemistry, 2008, 47(6):1579-1587.  
[37] DUVAL C, FRUCHART J C, STAELS B.PPAR alpha, fibrates, lipid metabolism and inflammation[J].Archives des Maladies du Coeur et des Vaisseaux, 2004, 97(6):665-672.
[38] DREYER C, KREY G, KELLER H, et al.Control of the peroxisomal beta-oxidation pathway by a novel family of nuclear hormone receptors[J].Cell, 1992, 68(5):879-887.  
[39] SCHOONJANS K, STAELS B, AUWERX J.The peroxisome proliferator activated receptors (PPARS) and their effects on lipid metabolism and adipocyte differentiation[J].Biochimica et Biophysica Acta, 1996, 1302(2):93-109.  
[40] NAKAGAWA S, KAWASHIMA Y, HIROSE A, et al.Regulation of hepatic level of fatty-acid-binding protein by hormones and clofibric acid in the rat[J].The Biochemical Journal, 1994, 297(Pt 3):581-584.