Formation of Bacterial Biofilm and Anti-Biofilm Activity of Antimicrobial Peptides

  • ZHANG Shanshan ,
  • SONG Jing ,
  • WANG Jiajun ,
  • SHAN Anshan
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  • College of Agriculture, Northeast Agricultural University, Harbin 150030, China

Received date: 2021-05-21

  Online published: 2021-12-16

Abstract

The formation process of bacterial biofilm is complex, including five stages of reversible attachment, irreversible attachment, formation of microflora, maturity of biofilm and bacteria shedding/diffusion, and the resistance of bacteria in the membrane is very high. In this paper, the characteristics and structure of biofilm are introduced in detail. The drug resistance mechanism of biofilm was analyzed. Some antimicrobial peptides with anti-biofilm activity and synergistic effect with antibiotics were briefly introduced, as well as nano drug delivery system which can improve the anti-biofilm effect of antimicrobial peptides. The anti-biofilm mechanism of antimicrobial peptides was described, hoping to provide reference for related research of bacterial biofilm.

Cite this article

ZHANG Shanshan , SONG Jing , WANG Jiajun , SHAN Anshan . Formation of Bacterial Biofilm and Anti-Biofilm Activity of Antimicrobial Peptides[J]. Chinese Journal of Animal Nutrition, 2021 , 33(12) : 6631 -6640 . DOI: 10.3969/j.issn.1006-267x.2021.12.004

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