[1] WYSS M,KADDURAH-DAOUK R.Creatine and creatinine metabolism[J].Physiological Reviews,2000,80(3):1107-1213.

[2] MACCORMICK V M,HILL L M,MACNEIL L,et al.Elevation of creatine in red blood cells in vegetarians and nonvegetarians after creatine supplementation[J].Canadian Journal of Applied Physiology,2004,29(6):704-713.

[3] MADDOCK R J,BIDNER B S,CARR S N,et al.Creatine monohydrate supplementation and the quality of fresh pork in normal and halothane carrier pigs[J].Journal of Animal Science,2002,80(4):997-1004.

[4] YOUNG J F,BERTRAM H C,ROSENVOLD K,et al.Dietary creatine monohydrate affects quality attributes of Duroc but not Landrace pork[J].Meat Science,2005,70(4):717-725.

[5] BURNS A F,GATLIN D M.Dietary creatine requirement of red drum (
Sciaenops ocellatus) and effects of water salinity on responses to creatine supplementation[J].Aquaculture,2019,506:320-324.
[6] MCBREAIRTY L E,ROBINSON J L,FURLONG K R,et al.Guanidinoacetate is more effective than creatine at enhancing tissue creatine stores while consequently limiting methionine availability in Yucatan miniature pigs[J].PLoS One,2015,10(6):e0131563.
[7] European Food Safety Authority.Safety and efficacy of guanidinoacetic acid as feed additive for chickens for fattening[J].EFSA Journal,2009,7(3):988.
[8] ÇENESIZ A A,YAVAŞ Ī,ÇIFTCI Ī,et al.Guanidinoacetic acid supplementation is favourable to broiler diets even containing poultry by-product meal[J].British Poultry Science,2020,61(3):311-319.

[9] LI J,ZHANG L,FU Y,et al.Creatine monohydrate and guanidinoacetic acid supplementation affects the growth performance,meat quality,and creatine metabolism of finishing pigs[J].Journal of Agricultural and Food Chemistry,2018,66(38):9952-9959.

[10] LIU Y,LI J L,LI Y J,et al.Effects of dietary supplementation of guanidinoacetic acid and combination of guanidinoacetic acid and betaine on postmortem glycolysis and meat quality of finishing pigs[J].Animal Feed Science and Technology,2015,205:82-89.
[11] 廖艳琴,张春晓.水产动物肌酸营养的研究进展[J].水产学报,2019,43(10):2084-2092. LIAO Y Q,ZHANG C X.Research progress of nutritional effects of creatine on aquatic animals[J].Journal of Fisheries of China,2019,43(10):2084-2092.(in Chinese)
[12] 赵元,许迟,吴仙花,等.不同浓度水平胍基乙酸对育肥猪肉品质影响的研究[J].中国饲料,2018,17(17):27-31. ZHAO Y,XU C,WU X H,et al.Study on effects of dietary supplementation guanidinoacetic acid (GAA) on fattening pork quality[J].China Feed,2018,17(17):27-31.(in Chinese)
[13] 潘宝海,孙冬岩,田耀耀.胍基乙酸对育肥猪生长性能、胴体品质及肉品质的影响[J].中国畜牧杂志,2016,52(19):38-41. PAN B H,SUN D Y,TIAN Y Y.Effects of guanidinoacetic acid on growth performance,carcass traits and meat quality in finishing pigs[J].Chinese Journal of Animal Science,2016,52(19):38-41.(in Chinese)
[14] 刘洋,李蛟龙,张林,等.胍基乙酸和甜菜碱对育肥猪肌肉能量代谢和肉品质的影响[J].畜牧兽医学报,2015,46(9):1557-1563. LIU Y,LI J L,ZHANG L,et al.Effects of dietary supplementation of guanidinoacetic acid and combination of guanidinoacetic acid and betaine on muscle energy metabolism,meat quality in finishing pigs[J].Acta Veterinaria Et Zootechnica Sinica,2015,46(9):1557-1563.(in Chinese)
[15] 程灵豪,高峰,温若竹,等.一水肌酸对肉鸭胴体组成及肌肉系水力的影响[J].浙江大学学报(农业与生命科学版),2010,36(6):635-640. CHENG L H,GAO F,WEN R Z,et al.Effect of creatine monohydrate on carcass characteristics and drip loss in meat duck[J].Journal of Zhejiang University(Agriculture & Life Sciences),2010,36(6):635-640.(in Chinese)
[16] 宋阳.胍基乙酸影响肌源性分化和肌肉生长的miRNA调控途径研究[D].硕士学位论文.雅安:四川农业大学,2019:45-49. SONG Y.Effects of guanylacetic acid on myogenic differentiation and muscle growth through the regulation of miRNA[D].Master's Thesis.Ya'an:Sichuan Agricultural University,2019:45-49.(in Chinese)
[17] 隋美霞,李法增,王宗伟,等.畜禽精氨酸营养研究进展[J].畜牧与兽医,2016,48(11):112-115. SUI M X,LI F Z,WANG Z W,et al.Progress of arginine in the study of animal nutrition[J].Animal Husbandry & Veterinary Medicine,2016,48(11):112-115.(in Chinese)
[18] 陈西风,刘维平.饲粮中补充不同水平精氨酸对肉鸡生长性能及免疫的影响[J].中国饲料,2019(21):51-53. CHEN X F,LIU W P.Effects of dietary arginine supplementation on growth performance and immune status of broiler chickens[J].China Feed,2019(21):51-53.(in Chinese)
[19] DILGER R N,BRYANT-ANGELONI K,PAYNE R L,et al.Dietary guanidino acetic acid is an efficacious replacement for arginine for young chicks[J].Poultry Science,2013,92(1):171-177.

[20] MICHIELS J,MAERTENS L,BUYSE J,et al.Supplementation of guanidinoacetic acid to broiler diets:effects on performance,carcass characteristics,meat quality,and energy metabolism[J].Poultry Science,2012,91(2):402-412.

[21] 王誉杰,张进威,王讯,等.胍基乙酸及代谢产物肌酸的研究进展[J].畜牧兽医学报,2018,49(8):1577-1584. WANG Y J,ZHANG J W,WANG X,et al.The research progress of guanidinoacetic acid and creatine[J].Acta Veterinaria Et Zootechnica Sinica,2018,49(8):1577-1584.(in Chinese)
[22] OSTOJIC S M.Advanced physiological roles of guanidinoacetic acid[J].European Journal of Nutrition,2015,54(8):1211-1215.

[23] STEAD L M,BROSNAN J T,BROSNAN M E,et al.Is it time to reevaluate methyl balance in humans?[J].The American Journal of Clinical Nutrition,2006,83(1):5-10.

[24] 赵景鹏,孙明发,李培勇,等.胍基乙酸对肉鸡的适用阶段及饲粮蛋氨酸配套强化效果研究[J].动物营养学报,2020,32(2):691-705. ZHAO J P,SUN M F,LI P Y,et al.Appropriate period of guanidinoacetic acid of broiler chickens and effects of dietary methionine fortification[J].Chinese Journal of Animal Nutrition,2020,32(2):691-705.(in Chinese)
[25] 解祥学,杜红方,陈书琴,等.蒸汽压片玉米及膨化大豆对犊牛腹泻、血液生化及抗氧化性能的影响[J].中国农业大学学报,2017,22(5):57-65. XIE X X,DU H F,CHEN S Q,et al.Effects of steam-flaked corn and extruded soybeans on diarrhea and blood parameters in veal calves[J].Journal of China Agricultural University,2017,22(5):57-65.(in Chinese)
[26] HALLIWELL B,WHITEMAN M.Measuring reactive species and oxidative damage
in vivo and in cell culture:how should you do it and what do the results mean?[J].British Journal of Pharmacology,2004,142(2):231-255.

[27] THANAN R,OIKAWA S,HIRAKU Y,et al.Oxidative stress and its significant roles in neurodegenerative diseases and cancer[J].International Journal of Molecular Sciences,2015,16(1):193-217.
[28] 阿娜尔,白东义,纳日嘎,等.不同抗氧化剂组合对蒙古马精液冷冻保存效果和抗氧化相关指标的影响[J].中国农业大学学报,2020,25(10):98-105. ANAER,BAI D Y,NARIGA,et al.Effects of antioxidants combination on cryopreservation and antioxidant activity of equine frozen semen[J].Journal of China Agricultural University,2020,25(10):98-105.(in Chinese)
[29] 李子平,田树飞,牛建东.不同蛋白质水平日粮添加胍基乙酸对热应激肉鸡生长性能、应激指标及肠道形态的影响[J].中国饲料,2020(4):59-63. LI Z P,TIAN S F,NIU J D.Effects of additional of guanidylacetic acid in different protein levels diets on growth performance,stress index and intestinal morphology of broilers exposed to heat stress[J].China Feed,2020(4):59-63.(in Chinese)
[30] 唐中元.磷酸肌酸对脂多糖诱导的RAW264.7的抗炎作用初步研究[D].硕士学位论文.长春:吉林大学,2020:6-9. TANG Z Y.Preliminary study on the anti-inflammatory effects of phosphocreatine on RAW264.7 induced by lipopolysaccharide[D].Master's Thesis.Changchun:Jilin University,2020:6-9.(in Chinese)
[31] CHU P,HAN G,AHSAN A,et al.Phosphocreatine protects endothelial cells from methylglyoxal induced oxidative stress and apoptosis via the regulation of PI3K/Akt/eNOS and NF-κB pathway[J].Vascular Pharmacology,2017,91:26-35.
[32] 李晓斌,马军,聂彪彪,等.补喂支链氨基酸、肌酸对伊犁马血浆生化指标的影响[J].新疆农业科学,2015,52(2):325-333. LI X B,MA J,NIE B B,et al.The effect of supplement with branched-chain amino acid,creatine on blood biochemical index of
Yili horse[J].Xinjiang Agricultural Sciences,2015,52(2):325-333.(in Chinese)
[33] MORI A,KOHNO M,MASUMIZU T,et al.Guanidino compounds generate reactive oxygen species[J].IUBMB Life,1996,40(1):135-143.

[34] 邹思湘.动物生物化学[M].5版.北京:中国农业出版社,2012:124-143. ZOU S X.Animal Biochemistry[M].5th ed.Beijing:China Agriculture Press,2012:124-143.(in Chinese)
[35] 洑琴,乔丽红,唐志刚,等.胍基乙酸对建鲤生产性能、体成分及肌肉能量代谢关键酶的影响[J].中国粮油学报,2015,30(3):85-89. FU Q,QIAO L H,TANG Z G,et al.Effects of guanidinoacetic acid on growth performance,body composition and key enzymes of energy metabolism of muscle in
Jian carp (
Cyprinus carpio var.Jian)[J].Journal of the Chinese Cereals and Oils Association,2015,30(3):85-89.(in Chinese)
[36] 邰宏飞,崔丽英.肌萎缩侧索硬化患者血清肌酐水平研究进展[J].中华内科杂志,2017,56(2):136-139. TAI H F,CUI L Y.Research progress of serum creatinine level in patients with amyotrophic lateral sclerosis[J].Chinese Journal of Internal Medicine,2017,56(2):136-139.(in Chinese)
[37] MEYER L E,MACHADO L B,SANTIAGO A P S A,et al.Mitochondrial creatine kinase activity prevents reactive oxygen species generation:antioxidant role of mitochondrial kinase-dependent adp re-cycling activity[J].Journal of Biological Chemistry,2006,281(49):7361-7371.
[38] 李蛟龙.一水肌酸和胍基乙酸对育肥猪肉质的影响及其作用机制研究[D].博士学位论文.南京:南京农业大学,2015:372-381. LI J L.Effects of creatine monohydrate and guanidinoacetic acid supplementation on meat quality of finishing pigs and mechanisms involved[D].Ph.D.Thesis.Nanjing:Nanjing Agricultural University,2015:372-381.(in Chinese)
[39] 刘洋.胍基乙酸和甜菜碱对育肥猪肉质和机体代谢的影响[D].硕士学位论文.南京:南京农业大学,2015:37-40. LIU Y.Effects of dietary supplementation of guanidinoacetic acid and betaine on meat quality and body metabolism of finishing pigs[D].Master's Thesis.Nanjing:Nanjing Agricultural University,2015:37-40.(in Chinese)
[40] PERSKY A M,BRAZEAU G A,HOCHHAUS G.Pharmacokinetics of the dietary supplement creatine[J].Clinical Pharmacokinetics,2003,42(6):557-574.

[41] 袁建琴,刘承宜,徐晓阳.骨骼肌肌酸转运及其分子机制[J].中国运动医学杂志,2009,28(3):345-348. YUAN J Q,LIU C Y,XU X Y.Skeletal muscle creatine transport and its molecular mechanism[J].Chinese Journal of Sports Medicine,2009,28(3):345-348.(in Chinese)
[42] LOIKE J D,ZALUTSKY D L,KABACK E,et al.Extracellular creatine regulates creatine transport in rat and human muscle cells[J].Proceedings of the National Academy of Sciences of the United States of America,1988,85(3):807-811.

[43] 苏琳,李慧姣,侯艳茹,等.一水肌酸及共轭亚油酸对小鼠肌纤维相关基因和酶活的影响及机理[J].食品科学2021,42(7):149-155. SU L,LI H J,HOU Y R,et al.Effects of dietary supplementation with creatine monohydrate and conjugated linoleic acid on muscle fiber-related gene expression and enzyme activities in mice[J].Food Science,2021,42(7):149-155.(in Chinese)
[44] 杜超.日粮中添加二甲双胍对育肥猪生产性能、血液指标、肉质以及
AMPK基因表达量的影响[D].硕士学位论文.沈阳:沈阳农业大学,2016:6-9. DU C.Effect of adding metformin in diet on finishing pig performance,blood index,meat quality and gene expression of
AMPK[D].Master's Thesis.Shenyang:Shenyang Agricultural University,2016:6-9.(in Chinese)
[45] 孙维琦,王路红,李环.AMPK细胞能量感受器研究进展[J].北华大学学报(自然科学版),2017,18(2):213-216. SUN W Q,WANG L H,LI H.Research progress on energy sensor-AMPK[J].Journal of Beihua University (Natural Science Edition),2017,18(2):213-216.(in Chinese)
[46] TACHIKAWA M,IKEDA S,FUJINAWA J,et al.γ-aminobutyric acid transporter 2 mediates the hepatic uptake of guanidinoacetate,the creatine biosynthetic precursor,in rats[J].PLoS One,2012,7(2):e32557.