[1] FRAMPTON J,MURPHY K G,FROST G,et al.Short-chain fatty acids as potential regulators of skeletal muscle metabolism and function[J].Nature Metabolism,2020,2(9):840-848.

[2] 刘壮.畜禽骨骼肌生长发育规律及其调控机制[J].饲料博览,2019(9):8-13. LIU Z.Growth and development of skeletal muscle in livestock and poultry and regulation mechanism[J].Feed Review,2019(9):8-13.(in Chinese)
[3] SACHECK J M,OHTSUKA A,MCLARY S C,et al.IGF-Ⅰ stimulates muscle growth by suppressing protein breakdown and expression of atrophy-related ubiquitin ligases,atrogin-1 and MuRF1[J].American Journal of Physiology.Endocrinology and Metabolism,2004,287(4):E591-E601.
[4] ORELLANA R A,SURYAWAN A,WILSON F A,et al.Development aggravates the severity of skeletal muscle catabolism induced by endotoxemia in neonatal pigs[J].American Journal of Physiology:Regulatory,Integrative and Comparative Physiology,2012,302(6):R682-R690.
[5] WANG X N,HU Z Y,HU J P,et al.Insulin resistance accelerates muscle protein degradation:activation of the ubiquitin-proteasome pathway by defects in muscle cell signaling[J].Endocrinology,2006,147(9):4160-4168.

[6] LAI K M V,GONZALEZ M,POUEYMIROU W T,et al.Conditional activation of akt in adult skeletal muscle induces rapid hypertrophy[J].Molecular and Cellular Biology,2004,24(21):9295-9304.

[7] BODINE S C,STITT T N,GONZALEZ M,et al.Akt/mTOR pathway is a crucial regulator of skeletal muscle hypertrophy and can prevent muscle atrophy
in vivo[J].Nature Cell Biology,2001,3(11):1014-1019.

[8] MILAN G,ROMANELLO V,PESCATORE F,et al.Regulation of autophagy and the ubiquitin-proteasome system by the FoxO transcriptional network during muscle atrophy[J].Nature Communications,2015,6:6670.
[9] SARBASSOV D D,GUERTIN D A,ALI S M,et al.Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex[J].Science,2005,307(5712):1098-1101.

[10] ZANCHI N E,LANCHA A H,Jr.Mechanical stimuli of skeletal muscle:implications on mTOR/p70s6k and protein synthesis[J].European Journal of Applied Physiology,2008,102(3):253-263.

[11] CROSSLAND H,CONSTANTIN-TEODOSIU D,GARDINER S M,et al.A potential role for Akt/FOXO signalling in both protein loss and the impairment of muscle carbohydrate oxidation during sepsis in rodent skeletal muscle[J].The Journal of Physiology,2008,586(22):5589-5600.

[12] COSTAMAGNA D,COSTELLI P,SAMPAOLESI M,et al.Role of inflammation in muscle homeostasis and myogenesis[J].Mediators of Inflammation,2015,2015:805172.
[13] BAKKAR N,GUTTRIDGE D C.NF-kappa B signaling:a tale of two pathways in skeletal myogenesis[J].Physiological Reviews,2010,90(2):495-511.

[14] PIJET B,PIJET M,LITWINIUK A,et al.TNF-α and IFN-s-dependent muscle decay is linked to NF-κB- and STAT-1α-stimulated
Atrogin1 and
MuRF1 genes in C2C12 myotubes[J].Mediators of Inflammation,2013,2013:171437.
[15] LECKER S H,GOLDBERG A L,MITCH W E.Protein degradation by the ubiquitin-proteasome pathway in normal and disease states[J].Journal of the American Society of Nephrology,2006,17(7):1807-1819.

[16] TRINDADE B C,CHEN G Y.NOD1 and NOD2 in inflammatory and infectious diseases[J].Immunological Reviews,2020,297(1):139-161.

[17] COLL C,LAMBERTY G,JENKINS R,et al.An integrative model for the study of developmental competencies in minority children[J].Child Development,1996,67(5):1891-1914.

[18] 曹婷,周汉林,荀文娟,等.
MSTN基因对猪骨骼肌发育调控的作用及其研究进展[J].基因组学与应用生物学,2017,36(4):1511-1517. CAO T,ZHOU H L,XUN W J,et al.The effect of
MSTN gene on the regulation of skeletal muscle development of pig and its research progress[J].Genomics and Applied Biology,2017,36(4):1511-1517.(in Chinese)
[19] ALLEN D L,UNTERMAN T G.Regulation of myostatin expression and myoblast differentiation by FoxO and SMAD transcription factors[J].American Journal of Physiology.Cell Physiology,2007,292(1):C188-C199.
[20] 阮井玲,甄鑫,刘娣,等.Myostatin通过Smad3下调
MyoD的表达来抑制骨骼肌卫星细胞的分化[J].中国生物工程杂志,2008,28(5):99-103. RUAN J L,ZHEN X,LIU D,et al.Myostatin inhibits myogenic satellite cell differentiation through down-regulating
MyoD expression by Smad3[J].China Biotechnology,2008,28(5):99-103.(in Chinese)
[21] CHELH I,PICARD B,HOCQUETTE J F,et al.Myostatin inactivation induces a similar muscle molecular signature in double-muscled cattle as in mice[J].Animal,2011,5(2):278-286.

[22] KAMBADUR R,SHARMA M,SMITH T P,et al.Mutations in myostatin (GDF8) in double-muscled Belgian blue and Piedmontese cattle[J].Genome Research,1997,7(9):910-916.

[23] MOSHER D S,QUIGNON P,BUSTAMANTE C D,et al.A mutation in the myostatin gene increases muscle mass and enhances racing performance in heterozygote dogs[J].PLoS Genetics,2007,3(5):e79.
[24] CHEN J F,MANDEL E M,THOMSON J M,et al.The role of microRNA-1 and microRNA-133 in skeletal muscle proliferation and differentiation[J].Nature Genetics,2006,38:228-233.
[25] HUANG Z Q,CHEN X L,YU B,et al.MicroRNA-27a promotes myoblast proliferation by targeting myostatin[J].Biochemical and Biophysical Research Communications,2012,423(2):265-269.

[26] JIA L,LI Y F,WU G F,et al.MiRNA-199a-3p regulates C2C12 myoblast differentiation through IGF-1/AKT/mTOR signal pathway[J].International Journal of Molecular Sciences,2013,15(1):296-308.

[27] MOHAMED J S,HAJIRA A,PARDO P S,et al.MicroRNA-149 inhibits PARP-2 and promotes mitochondrial biogenesis via SIRT-1/PGC-1α network in skeletal muscle[J].Diabetes,2014,63(5):1546-1559.

[28] XU J,LI R S,WORKENEH B,et al.Transcription factor FoxO1,the dominant mediator of muscle wasting in chronic kidney disease,is inhibited by microRNA-486[J].Kidney International,2012,82(4):401-411.

[29] HITACHI K,TSUCHIDA K.Role of microRNAs in skeletal muscle hypertrophy[J].Frontiers in Physiology,2013,4:408.
[30] SALMINEN A,KAARNIRANTA K.AMP-activated protein kinase (AMPK) controls the aging process via an integrated signaling network[J].Ageing Research Reviews,2012,11(2):230-241.

[31] KIMURA N,TOKUNAGA C,DALAL S,et al.A possible linkage between AMP-activated protein kinase (AMPK) and mammalian target of rapamycin (mTOR) signalling pathway[J].Genes to Cells,2003,8(1):65-79.

[32] 刘启梁.eEF2K与肿瘤[J].生命的化学,2016,36(5):633-638. LIU Q L.Eukaryotic elongation factor 2 kinase and cancer[J].Chemistry of Life,2016,36(5):633-638.(in Chinese)
[33] JENSEN T E,WOJTASZEWSKI J F P,RICHTER E A.AMP-activated protein kinase in contraction regulation of skeletal muscle metabolism:necessary and/or sufficient?[J].Acta Physiologica,2009,196(1):155-174.

[34] 王佳明.热应激下ABCG2介导AMPK通路调节肉鸡肌肉生长发育及机理[D].硕士学位论文.合肥:安徽农业大学,2019. WANG J M.ABCG2-mediated AMPK pathway regulates muscle growth and development in broilers under heat stress[D].Master's Thesis.Hefei:Anhui Agricultural University,2019.(in Chinese)
[35] KRAWIEC B J,NYSTROM G J,FROST R A,et al.AMP-activated protein kinase agonists increase mRNA content of the muscle-specific ubiquitin ligases MAFbx and MuRF1 in C2C12 cells[J].American Journal of Physiology.Endocrinology and Metabolism,2007,292(6):E1555-E1567.
[36] 任阳.饱和与不饱和脂肪酸对猪肌纤维组成的影响及其AMPK途径研究[D].博士学位论文.杭州:浙江大学,2014. REN Y.Effect of saturated and unsaturated fatty acids on porcine muscle fiber composition and AMPK expression[D].Ph.D.Thesis.Hangzhou:Zhejiang University,2014.(in Chinese)
[37] MARIÑO E,RICHARDS J L,MCLEOD K H,et al.Gut microbial metabolites limit the frequency of autoimmune T cells and protect against type 1 diabetes[J].Nature Immunology,2017,18(5):552-562.

[38] LAHIRI S,KIM H,GARCIA-PEREZ I,et al.The gut microbiota influences skeletal muscle mass and function in mice[J].Science Translational Medicine,2019,11(502):eaan5662.
[39] BINDELS L B,BECK R,SCHAKMAN O,et al.Restoring specific lactobacilli levels decreases inflammation and muscle atrophy markers in an acute leukemia mouse model[J].PLoS One,2012,7(6):e37971.
[40] YAN J,HERZOG J W,TSANG K,et al.Gut microbiota induce IGF-1 and promote bone formation and growth[J].Proceedings of the National Academy of Sciences of the United States of America,2016,113(47):E7554-E7563.
[41] JANG H M,HAN S K,KIM J K,et al.
Lactobacillus sakei alleviates high-fat-diet-induced obesity and anxiety in mice by inducing AMPK activation and
SIRT1 expression and inhibiting gut microbiota-mediated NF-κB activation[J].Molecular Nutrition & Food Research,2019,63(6):e1800978.
[42] RUSSELL S T,TISDALE M J.Mechanism of attenuation by beta-hydroxy-beta-methylbutyrate of muscle protein degradation induced by lipopolysaccharide[J].Molecular and Cellular Biochemistry,2009,330(1/2):171-179.
[43] SEALE P,BJORK B,YANG W L,et al.PRDM16 controls a brown fat/skeletal muscle Switch[J].Nature,2008,454(7207):961-967.

[44] BRYNER R W,WOODWORTH-HOBBS M E,WILLIAMSON D L,et al.Docosahexaenoic acid protects muscle cells from palmitate-induced atrophy[J].ISRN Obesity,2012,2012:647348.
[45] WOODWORTH-HOBBS M E,HUDSON M B,RAHNERT J A,et al.Docosahexaenoic acid prevents palmitate-induced activation of proteolytic systems in C2C12 myotubes[J].The Journal of Nutritional Biochemistry,2014,25(8):868-874.

[46] ANDRÉE-ANNE G,WHITE P J,CHOUINARD P Y,et al.Long-chain omega-3 fatty acids regulate bovine whole-body protein metabolism by promoting muscle insulin signalling to the Akt-mTOR-S6K1 pathway and insulin sensitivity[J].The Journal of Physiology,2007,579(1):269-284
[47] GINGRAS A A,WHITE P J,CHOUINARD P Y,et al.Long-chain omega-3 fatty acids regulate bovine whole-body protein metabolism by promoting muscle insulin signalling to the Akt-Mtor-S6K1 pathway and insulin sensitivity[J].The Journal of Physiology,2007,579(1):269-284.

[48] 陈逢.鱼油通过TLR4和NOD信号通路对脂多糖诱导的仔猪肠道、肝脏损伤和肌肉蛋白质降解的调控作用[D].硕士学位论文.武汉:武汉轻工大学,2013. CHEN F.Regulative role of fish oil on intestinal and liver injury,and muscle protein degradation of piglets after lipopolysaccharide challenge through TLR4 and NOD signaling pathway[D].Master's Thesis.Wuhan:Wuhan Polytechnic University,2013.(in Chinese)
[49] NARDI F,HOFFMANN T M,STRETTON C,et al.Proteasomal modulation of cellular SNAT2(SLC38A2) abundance and function by unsaturated fatty acid availability[J].The Journal of Biological Chemistry,2015,290(13):8173-8184.

[50] CHEN Q,LIU Q,SUN Q X,et al.Flavour formation from hydrolysis of pork sarcoplasmic protein extract by a unique LAB culture isolated from Harbin dry sausage[J].Meat Science,2015,100:110-117.
[51] GUICHARD E.Interactions between flavor compounds and food ingredients and their influence on flavor perception[J].Food Reviews International,2002,18(1):49-70.

[52] WU S Y,PÉREZ M D,PUYOL P,et al.Beta-lactoglobulin binds palmitate within its central cavity[J].The Journal of Biological Chemistry,1999,274(1):170-174.

[53] BOYER C,JOANDEL S,ROUSSILHES V,et al.Heat-induced gelation of myofibrillar proteins and myosin from fast- and slow-twitch rabbit muscles[J].Journal of Food Science,1996,61(6):1138-1143.

[54] 周昌瑜,蒋娅婷,曹锦轩,等.肌原纤维蛋白浓度对风味物质吸附能力的影响[J].核农学报,2016,30(5):904-911. ZHOU C Y,JIANG Y T,CAO J X,et al.Effect of the myofibril proteins concentrations on the adsorbing capacity for the flavor compounds[J].Journal of Nuclear Agricultural Sciences,2016,30(5):904-911.(in Chinese)
[55] 吕彤,林俊杰,周昌瑜,等.热处理强度对猪肉肌球蛋白结构及风味成分吸附特性的影响[J].农业工程学报,2016,32(8):285-291. LV T,LIN J J,ZHOU C Y,et al.Effect of heat treatment intensity on structure and binding capacity of volatile compounds of myosin[J].Transactions of the Chinese Society of Agricultural Engineering,2016,32(8):285-291.(in Chinese)
[56] O'NEILL E,MORRISSEY P A,MULVIHILL D M.The surface-active properties of muscle proteins[J].Food Chemistry,1990,35(1):1-12.

[57] TAN Y, SIEBERT K J. Modeling bovine serum albumin binding of flavor compounds (alcohols,aldehydes,esters,and ketones) as a function of molecular properties[J].Journal of Food Science,2007,73(1):56-63.

[58] PÉREZ-JUAN M,FLORES M,TOLDRÁ F.Binding of aroma compounds by isolated myofibrillar proteins:effect of protein concentration and conformation[J].Food Chemistry,2007,105(3):932-939.

[59] WANG K,ARNTFIELD S D.Effect of protein-flavour binding on flavour delivery and protein functional properties:a special emphasis on plant-based proteins[J].Flavour and Fragrance Journal,2017,32(2):92-101.

[60] LEDWARD D A.Post-slaughter influences on the formation of metyyoglobin in beef muscles[J].Meat Science,1985,15(3):149-171.

[61] OFFER G,KNIGHT P,JEACOCKE R,et al.The structural basis of the water-holding,appearance and toughness of meat and meat products[J].Food Struture,1989,8(1):17.
[62] 魏秀丽,谢小雷,张春晖,等.猪宰后肌肉体系中μ-calpain及肌原纤维蛋白理化特性的变化规律[J].中国农业科学,2015,48(12):2428-2438. WEI X L,XIE X L,ZHANG C H,et al.The variations inμ-calpain and physico-chemical characteristics of myofibrillar proteins in postmortem porcine muscle[J].Scientia Agricultura Sinica,2015,48(12):2428-2438.(in Chinese)
[63] HO C Y,STROMER M H,ROBSON R M.Identification of the 30 kDa polypeptide in post mortem skeletal muscle as a degradation product of troponin-T[J].Biochimie,1994,76(5):369-375.

[64] KOOHMARAIE M.Biochemical factors regulating the toughening and tenderization processes of meat[J].Meat Science,1996,43(S1):193-201.
[65] TAKAHASHI K.Structural weakening of skeletal muscle tissue during post-mortem ageing of meat:the non-enzymatic mechanism of meat tenderization[J].Meat Science,1996,43(S1):67-80.
[66] OKITANI A,ICHINOSE N,ITOH J,et al.Liberation of actin from actomyosin in meats heated to 65℃[J].Meat Science,2009,81(3):446-450.

[67] HUANG H G,LARSEN M R,PALMISANO G,et al.Quantitative phosphoproteomic analysis of porcine muscle within 24h postmortem[J].Journal of Proteomics,2014,106:125-139.