Research Progress on Regulation of Protein Metabolism in Animal Muscle Tissue

  • DOU Lu ,
  • LIU Chang ,
  • YANG Zhihao ,
  • JIN Ye
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  • College of Food Science and Engineering, Inner Mongolia Agricultural University, Hohhot 010018, China

Received date: 2021-06-22

  Online published: 2022-01-18

Abstract

Animal muscle protein is an important protein which maintains the normal physiological functions of the body, and it is also an important factor that affects the characteristics of meat quality. Studies have shown that animal muscle protein metabolism is completed by multiple signaling pathways such as insulin-like growth factor-1 (IGF-1)/phosphatidylinositol 3-kinase (PI3K)/protein kinase B (Akt), tumor necrosis factor-α (TNF-α)/nuclear transcription factor-κB (NF-κB) and myostatin (MSTN)/Smadt. In addition, muscle protein metabolism is regulated by miRNA, AMP-activated protein kinase (AMPK), intestinal microbes and fatty acid. Therefore, this article systematically elaborates on the signal pathways, regulation mechanisms of muscle protein metabolism and its effects on meat quality, in order to improve and enrich the network regulation mechanism of skeletal muscle development and metabolism, which will provide a theoretical basis for improving meat quality through genetic and nutrition measures in the future.

Cite this article

DOU Lu , LIU Chang , YANG Zhihao , JIN Ye . Research Progress on Regulation of Protein Metabolism in Animal Muscle Tissue[J]. Chinese Journal of Animal Nutrition, 2022 , 34(1) : 39 -50 . DOI: 10.3969/j.issn.1006-267x.2022.01.005

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