Effects of Different Forms of Zinc Oxide on Growth Performance and Intestinal Health of Weaned Piglets

LIU Hansuo; PIAO Xiangshu; MA Hong; HE Pingli; LIU Li

doi:10.3969/j.issn.1006-267x.2022.02.016

Chinese Journal of Animal Nutrition >

2022 , Vol. 34 >Issue 2: 818 - 829

DOI: https://doi.org/10.3969/j.issn.1006-267x.2022.02.016

RESEARCH PAPER

Effects of Different Forms of Zinc Oxide on Growth Performance and Intestinal Health of Weaned Piglets

LIU Hansuo ,
PIAO Xiangshu ,
MA Hong ,
HE Pingli ,
LIU Li

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1. State Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China;
2. Tianjin Zhongsheng Feed Co., Ltd., Tianjin 300380, China

Received date: 2021-07-05

Online published: 2022-02-15

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Abstract

This experiment was conducted to investigate the effects of different forms of zinc oxide on growth performance, nutrient apparent digestibility, serum antioxidant capacity and intestinal morphology of weaned piglets. In a completely randomized block design, a total of 144 healthy three-way (Duroc×Landrace×Yorkshire) crossbred weaned piglets of (6.42±0.51) kg were divided into 3 groups with 6 replicates per group and 8 pigs per replicate. The experiment lasted for 28 days and was divided into two stages as early stage (days 1 to 14) and late stage (days 15 to 28). The groups were as follows:ordinary zinc oxide group (basal diet supplemented with 1 600 mg/kg ordinary zinc oxide in early stage and 110 mg/kg in late stage, calculated as zinc); passivated zinc oxide group (basal diet supplemented with 1 600 mg/kg passivated zinc oxide in early stage and 110 mg/kg in late stage, calculated as zinc); nano zinc oxide group (basal diet supplemented with 1 600 mg/kg nano zinc oxide in early stage and 110 mg/kg in late stage, calculated as zinc). The basal diet was corn-soybean meal type. The results showed as follows:1) in the early stage, compared with ordinary zinc oxide group, the body weight on day 14 and average daily gain of weaned piglets in passivated zinc oxide group were significantly increased (P<0.05), and the ratio of feed to gain was significantly decreased (P<0.05); the diarrhea rate in passivated zinc oxide group and nano zinc oxide group was significantly decreased (P<0.05). During the whole experiment period (days 1 to 28), compared with ordinary zinc oxide group, the diarrhea rate of weaned piglets in passivated zinc oxide group and nano zinc oxide group was significantly decreased (P<0.05). 2) In the later stage of the experiment, compared with ordinary zinc oxide group, the apparent digestibility of organic matter and crude protein of weaned piglets in passivated zinc oxide group was significantly increased (P<0.05), and the apparent digestibility of dry matter, gross energy, calcium and phosphorus of weaned piglets in passivated zinc oxide group and nano zinc oxide group was significantly increased (P<0.05). 3) Compared with ordinary zinc oxide group, zinc content in liver and stomach digesta of weaned piglets in passivated zinc oxide group and nano zinc oxide group was significantly increased (P<0.05). 4) Compared with ordinary zinc oxide group, the expression level of occludin in jejunum of weaned piglets in nano zinc oxide group was significantly increased (P<0.05), and the expression levels of zonula occluden-1 (ZO-1) (P=0.08) and claudin-1 (P=0.07) in jejunum tended to be increased. In conclusion, compared with ordinary zinc oxide, dietary supplemented with passivated zinc oxide and nano zinc oxide can improve dietary nutrient apparent digestibility and jejunum tight junction protein expression, reduce diarrhea rate, and have positive effects on intestinal health and growth performance of weaned piglets.

Key words： weaned piglets; zinc oxide; growth performance; intestinal health

Cite this article

LIU Hansuo , PIAO Xiangshu , MA Hong , HE Pingli , LIU Li . Effects of Different Forms of Zinc Oxide on Growth Performance and Intestinal Health of Weaned Piglets[J]. Chinese Journal of Animal Nutrition, 2022 , 34(2) : 818 -829 . DOI: 10.3969/j.issn.1006-267x.2022.02.016

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