RESEARCH PAPER

Effects of Antimicrobial Peptide on Growth Performance, Nutrient Apparent Digestibilities and Intestinal Flora of Growing Female Minks

  • YU Xiaojun ,
  • LI Dandan ,
  • WANG Luyi ,
  • GUO Zhihao ,
  • WANG Guang ,
  • WANG Lihua
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  • College of Animal Science and Technology, Qingdao Agricultural University, Qingdao 266109, China

Received date: 2021-07-08

  Online published: 2022-02-15

Abstract

The present experiment was conducted to explore the effects of antimicrobial peptide on growth performance, nutrient apparent digestibilities and intestinal flora of growing female minks. Sixty short-haired black female minks with similar body weight at 65 days of age were selected and divided into 6 groups with 10 replicates per group and 1 mink per replicate. Minks in six groups were fed basal diets supplemented with 0 (control group), 100, 200, 300, 400 and 500 mg/kg antimicrobial peptide, respectively. The pre-test lasted for 1 week, and the experiment lasted for 8 weeks. The results showed as follows:1) compared with the control group, the final weight and average daily gain of 200 mg/kg antimicrobial peptide addition group were significantly increased (P<0.05), and the body length of 100, 200, 400 and 500 mg/kg antimicrobial peptide addition groups was significantly increased (P<0.05). 2) Compared with the control group, the crude protein apparent digestibility during 1 to 5 weeks of 200, 300 and 400 mg/kg antimicrobial peptide addition groups was significantly increased (P<0.05), and the ether extract apparent digestibility during 6 to 8 weeks of 100, 200, 300 and 400 mg/kg antimicrobial peptide addition groups was significantly increased (P<0.05). 3) Compared with the control group, the Ace index of 200 and 300 mg/kg antimicrobial peptide addition groups was significantly increased (P<0.05), and the Chao1 index of 300 mg/kg antimicrobial peptide addition group was significantly increased (P<0.05). At the phylum level, compared with the control group, the Firmicutes relative abundance of 100 and 200 mg/kg antimicrobial peptide addition groups was significantly increased (P<0.05), and the Proteobacteria relative abundance of 100, 200 and 300 mg/kg antimicrobial peptide addition groups was significantly decreased (P<0.05). At the genus level, compared with the control group, the Lactobacillus relative abundance of 200 and 300 mg/kg antimicrobial peptide addition groups was significantly increased (P<0.05), the Burkholderia relative abundance of 400 mg/kg antimicrobial peptide addition group was significantly increased (P<0.05), and the Clostridium relative abundance of 100, 200, 300, 400 and 500 mg/kg antimicrobial peptide addition groups was significantly decreased (P<0.05). In conclusion, under this experimental condition, dietary supplemented with 100 and 200 mg/kg antimicrobial peptide can improve final weight, average daily gain, body length and apparent digestibilities of crude peotein and ether extract, adjust the diversity of intestinal flora, increase the relative abundance of Firmicutes and Lactobacillus, and decrease the relative abundance of Proteobacteria and Clostridium of growing female minks.

Cite this article

YU Xiaojun , LI Dandan , WANG Luyi , GUO Zhihao , WANG Guang , WANG Lihua . Effects of Antimicrobial Peptide on Growth Performance, Nutrient Apparent Digestibilities and Intestinal Flora of Growing Female Minks[J]. Chinese Journal of Animal Nutrition, 2022 , 34(2) : 1194 -1204 . DOI: 10.3969/j.issn.1006-267x.2022.02.051

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