[1] FERENC K, PIETRZAK P, GODLEWSKI M M, et al.Intrauterine growth retarded piglet as a model for humans-studies on the perinatal development of the gut structure and function[J].Reproductive Biology, 2014, 14(1):51-60.

[2] 孔祥峰, 伍国耀, 印遇龙.猪宫内生长迟缓及其防治研究进展[J].畜牧与兽医, 2009, 41(10):96-101. KONG X F, WU G Y, YIN Y L.Advances of intrauterine growth retardation in pigs[J].Animal Husbandry & Veterinary Medicine, 2009, 41(10):96-101.(in Chinese)
[3] LUISSINT A C, PARKOS C A, NUSRAT A.Inflammation and the intestinal barrier:leukocyte-epithelial cell interactions, cell junction remodeling, and mucosal repair[J].Gastroenterology, 2016, 151(4):616-632.

[4] WANG J J, CHEN L X, LI D F, et al.Intrauterine growth restriction affects the proteomes of the small intestine, liver, and skeletal muscle in newborn pigs[J].The Journal of Nutrition, 2008, 138(1):60-66.

[5] OLSZEWSKI J, ZABIELSKI R, SKRZYPEK T, et al.Differences in intestinal barrier development between intrauterine growth restricted and normal birth weight piglets[J].Animals, 2021, 11(4):990.
[6] WANG W, DEGROOTE J, VAN GINNEKEN C, et al.Intrauterine growth restriction in neonatal piglets affects small intestinal mucosal permeability and mRNA expression of redox-sensitive genes[J].FASEB Journal, 2016, 30(2):863-873.

[7] FERENC K, PIETRZAK P, WIERZBICKA M, et al.Alterations in the liver of intrauterine growth retarded piglets may predispose to development of insulin resistance and obesity in later life[J].Journal of Physiology and Pharmacology, 2018, 69(2):211-218.
[8] MCELRATH T F, ALLRED E N, VAN MARTER L, et al.Perinatal systemic inflammatory responses of growth-restricted preterm newborns[J].Acta Paediatrica, 2013, 102(10):e439-e442.
[9] D'INCA R, KLOAREG M, GRAS-LE GUEN C, et al.Intrauterine growth restriction modifies the developmental pattern of intestinal structure, transcriptomic profile, and bacterial colonization in neonatal pigs[J].The Journal of Nutrition, 2010, 140(5):925-931.

[10] ZHANG W, MA C, XIE P, et al.Gut microbiota of newborn piglets with intrauterine growth restriction have lower diversity and different taxonomic abundances[J].Journal of Applied Microbiology, 2019, 127(2):354-369.

[11] XIONG L, YOU J M, ZHANG W H, et al.Intrauterine growth restriction alters growth performance, plasma hormones, and small intestinal microbial communities in growing-finishing pigs[J].Journal of Animal Science and Biotechnology, 2020, 11(1):86.
[12] TURNER J R.Molecular basis of epithelial barrier regulation:from basic mechanisms to clinical application[J].The American Journal of Pathology, 2006, 169(6):1901-1909.

[13] BAUER R, WALTER B, HOPPE A, et al.Body weight distribution and organ size in newborn swine (
sus scrofa domestica)-a study describing an animal model for asymmetrical intrauterine growth retardation[J].Experimental and Toxicologic Pathology, 1998, 50(1):59-65.

[14] GEHART H, CLEVERS H.Tales from the crypt:new insights into intestinal stem cells[J].Nature Reviews Gastroenterology & Hepatology, 2019, 16(1):19-34.

[15] SU W P, ZHANG H, YING Z X, et al.Effects of dietary
L-methionine supplementation on intestinal integrity and oxidative status in intrauterine growth-retarded weanling piglets[J].European Journal of Nutrition, 2018, 57(8):2735-2745.

[16] LI Y, ZHANG H, SU W P, et al.Effects of dietary
Bacillus amyloliquefaciens supplementation on growth performance, intestinal morphology, inflammatory response, and microbiota of intra-uterine growth retarded weanling piglets[J].Journal of Animal Science and Biotechnology, 2018, 9:22.
[17] TRAHAIR J F, SANGILD P T.Systemic and luminal influences on the perinatal development of the gut[J].Equine Veterinary Journal, 1997, 29(S24):40-50.
[18] ZHONG X, WANG T, ZHANG X H, et al.Heat shock protein 70 is upregulated in the intestine of intrauterine growth retardation piglets[J].Cell Stress & Chaperones, 2010, 15(3):335-342.

[19] FRANK D N, ST AMAND A L, FELDMAN R A, et al.Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases[J].Proceedings of the National Academy of Sciences of the United States of America, 2007, 104(34):13780-13785.

[20] 宗秋芳, 钦伟云, 霍永久, 等.猪肠上皮紧密连接蛋白研究进展[J].浙江农业学报, 2018, 30(8):1435-1444. ZONG Q F, QIN W Y, HUO Y J, et al.Research progress of intestinal epithelial tight junction proteins in piglets[J].Acta Agriculturae Zhejiangensis, 2018, 30(8):1435-1444.(in Chinese)
[21] YAN T, ZHANG F, HE Y, et al.
Enterococcus faecium HDRsEf1 elevates the intestinal barrier defense against enterotoxigenic
Escherichia coli and regulates occludin expression via activation of TLR-2 and PI3K signalling pathways[J].Letters in Applied Microbiology, 2018, 67(5):520-527.

[22] ANDREWS C, MCLEAN M H, DURUM S K.Cytokine tuning of intestinal epithelial function[J].Frontiers in Immunology, 2018, 9:1270.
[23] AL-SADI R, BOIVIN M, MA T.Mechanism of cytokine modulation of epithelial tight junction barrier[J].Frontiers in Bioscience (Landmark Edition), 2009, 14:2765-2778.
[24] WANG X Q, WU W Z, LIN G, et al.Temporal proteomic analysis reveals continuous impairment of intestinal development in neonatal piglets with intrauterine growth restriction[J].Journal of Proteome Research, 2010, 9(2):924-935.