REVIEW

Advances of Dynamic Changes of Extracellular Matrix Network and Its Regulating Effects on Nutrient Metabolism

  • LIU Chunyan ,
  • WANG Li ,
  • JIANG Zongyong ,
  • YI Hongbo
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  • 1. Guangdong Key Laboratory of Animal Breeding and Nutrition, Maoming Branch of Guangdong Laboratory for Lingnan Modern Agriculture, Key Laboratory of Animal Nutrition and Feed Science in South China, Ministry of Agriculture and Rural Affairs, State Key Laboratory of Livestock and Poultry Breeding, Institute of Animal Science, Guangdong Academy of Agricultural Sciences, Guangzhou 510640, China;
    2. College of Animal Science and Technology, Guangxi University, Nanning 530004, China

Received date: 2021-08-31

  Online published: 2022-03-14

Abstract

Extracellular matrix (ECM) is a dynamic multifunctional network structure, which is the external environment for the survival of cells and tissues. The ECM network has long been regarded as regulators of various physiological functions, such as cell growth, adhesion and tissue remodeling. Recent studies have found that the ECM network is a physiological barrier for the gradual transport of nutrients such as amino acids. When ECM network is absent or over deposited, it will lead to metabolic abnormalities, indicating that ECM network is involved in the regulation of nutrient transport and metabolism. However, the role and mechanism of ECM network on nutrient metabolism remain unclear. Therefore, this article reviewed the physiological barrier function and dynamic changes of ECM network and its regulation on the transport and metabolism of nutrients such as amino acids, in order to provide new ideas for improving the utilization efficiency and production performance of livestock and poultry.

Cite this article

LIU Chunyan , WANG Li , JIANG Zongyong , YI Hongbo . Advances of Dynamic Changes of Extracellular Matrix Network and Its Regulating Effects on Nutrient Metabolism[J]. Chinese Journal of Animal Nutrition, 2022 , 34(3) : 1446 -1455 . DOI: 10.3969/j.issn.1006-267x.2022.03.009

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