Effects of Resveratrol on Growth Performance, Serum Biochemical Indexes and Antioxidant Capacity of Broilers

MA Zheng; KANG Shouting; CAI Fenglong; QIN Shunyi; LI Liuan; YANG Hua; ZHANG Jianbin

doi:10.3969/j.issn.1006-267x.2022.03.019

Chinese Journal of Animal Nutrition >

2022 , Vol. 34 >Issue 3: 1559 - 1568

DOI: https://doi.org/10.3969/j.issn.1006-267x.2022.03.019

RESEARCH PAPER

Effects of Resveratrol on Growth Performance, Serum Biochemical Indexes and Antioxidant Capacity of Broilers

MA Zheng ,
KANG Shouting ,
CAI Fenglong ,
QIN Shunyi ,
LI Liuan ,
YANG Hua ,
ZHANG Jianbin

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1. Tianjin Key Laboratory of Agricultural Animal Breeding and Healthy Breeding, Department of Animal Science and Veterinary Medicine, Tianjin Agricultural University, Tianjin 300384, China;
2. College of Pharmacy, Heze University, Heze 274015, China;
3. Tianjin Guangyuan Livestock and Poultry Breeding Co., Ltd., Tianjin 301824, China

Received date: 2021-08-12

Online published: 2022-03-14

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Abstract

This experiment was conducted to study the effects of resveratrol (RES) on growth performance, serum biochemical indexes and antioxidant capacity of broilers. A total of 480 one-day-old Ross 308 broilers were randomly divided into 4 groups with 6 replicates in each group and 20 broilers per replicate. Broilers in group A (control group) were fed a basal diet, those in group B, group C and group D were fed the basal diet supplemented with RES at levels of 200, 500 and 800 mg/kg, respectively. The experiment lasted for 42 days. The results showed as follows:1) compared with group A, the experimental groups had no significant difference in average daily gain, average daily feed intake and feed/gain (P>0.05). 2) There was no significant difference between the experimental groups and group A in serum aspartate aminotransferase activity, glucose, albumin, uric acid, urea, triglyceride and cholesterol contents at 21 and 42 days of age (P>0.05); serum total protein content in group C was significantly lower than that in group A at 42 days of age (P<0.05); serum high density lipoprotein cholesterol content in groups B and C was significantly higher than that in group A at 42 days of age (P<0.05); serum low density lipoprotein cholesterol content in groups C and D was significantly lower than that in group A at 21 days of age (P<0.05). 3) There was no significant difference between the experimental groups and the group A in serum immunoglobulin A and complement 4 contents at 21 and 42 days of age (P>0.05); the content of serum immunoglobulin M in group A was significantly higher than that in group D at 42 days of age (P<0.05). 4) Compared with group A, serum total antioxidant capacity and total superoxide dismutase (T-SOD) activity in group C were significantly increased (P<0.05); the basic diet supplemented with RES significantly increased the activity of serum glutathione peroxidase (GSH-Px) (P<0.05). 5) Compared with group A, heart index, liver index, spleen index and glandular stomach index of broilers in group D were significantly increased (P<0.05). It can be seen that adding RES can significantly improve the antioxidant capacity of broilers, and the supplemental level of 500 mg/kg has a better benefit; it can reduce the contents of cholesterol and low density lipoprotein cholesterol in serum, increase the content of high density lipoprotein cholesterol, and improve the body's lipid metabolism.

Key words： resveratrol; broilers; growth performance; serum biochemistry; antioxidant capacity

Cite this article

MA Zheng , KANG Shouting , CAI Fenglong , QIN Shunyi , LI Liuan , YANG Hua , ZHANG Jianbin . Effects of Resveratrol on Growth Performance, Serum Biochemical Indexes and Antioxidant Capacity of Broilers[J]. Chinese Journal of Animal Nutrition, 2022 , 34(3) : 1559 -1568 . DOI: 10.3969/j.issn.1006-267x.2022.03.019

References

[1] 孟庆维,吴芊慧,石宝明,等.白藜芦醇在猪营养中的研究进展[J].动物营养学报,2021,33(3):1216-1222. MENG Q W,WU Q H,SHI B M,et al.Research progress of resveratrol in pig nutrition[J].Chinese Journal of Animal Nutrition,2021,33(3):1216-1222.(in Chinese)
[2] LAI X,CAO M,SONG X,et al.Resveratrol promotes recovery of immune function of immunosuppressive mice by activating JNK/NF-κB pathway in splenic lymphocytes[J].Canadian Journal of Physiology and Pharmacology,2017,95(6):763-767.

[3] JIN X L,WANG K,LIU H Y,et al.Protection of bovine mammary epithelial cells from hydrogen peroxide-induced oxidative cell damage by resveratrol[J].Oxidative Medicine and Cellular Longevity,2016,2016:2572175.
[4] VESTERGAARD M,INGMER H.Antibacterial and antifungal properties of resveratrol[J].International Journal of Antimicrobial Agents,2019,53(6):716-723.

[5] ZHOU Z X,MOU S F,CHEN X Q,et al.Anti-inflammatory activity of resveratrol prevents inflammation by inhibiting NF-κB in animal models of acute pharyngitis[J].Molecular Medicine Reports,2018,17(1):1269-1274.
[6] KO J H,SETHI G,UM J Y,et al.The role of resveratrol in cancer therapy[J].International Journal of Molecular Sciences,2017,18(12):2589.
[7] ZHANG H Z,CHEN D W,HE J,et al.Long-term dietary resveratrol supplementation decreased serum lipids levels,improved intramuscular fat content,and changed the expression of several lipid metabolism-related miRNAs and genes in growing-finishing pigs[J].Journal of Animal Science,2019,97(4):1745-1756.

[8] CHEN X L,ZENG Z Y,HUANG Z Q,et al.Effects of dietary resveratrol supplementation on immunity, antioxidative capacity and intestinal barrier function in weaning piglets[J].Animal Biotechnology,2021,32(2):240-245.

[9] RENAUD S,DE LORGERIL M.Wine,alcohol,platelets,and the French paradox for coronary heart disease[J].Lancet,1992,339(8808):1523-1526.

[10] LIPPI G,FRANCHINI M,FAVALORO E J,et al.Moderate red wine consumption and cardiovascular disease risk:beyond the"French paradox"[J].Seminars in Thrombosis and Hemostasis,2010,36(1):59-70.

[11] MENG Q W,SUN S S,BAI Y S,et al.Effects of dietary resveratrol supplementation in sows on antioxidative status,myofiber characteristic and meat quality of offspring[J].Meat Science,2020,167:108176.
[12] ZHANG C,WANG L,ZHAO X H,et al.Dietary resveratrol supplementation prevents transport-stress-impaired meat quality of broilers through maintaining muscle energy metabolism and antioxidant status[J].Poultry Science,2017,96(7):2219-2225.

[13] LV C R,LARBI A,WU G Q,et al.Improving the quality of cryopreserved goat semen with a commercial bull extender supplemented with resveratrol[J].Animal Reproduction Science,2019,208:106127.
[14] LIU L L,HE J H,XIE H B,et al.Resveratrol induces antioxidant and heat shock protein mRNA expression in response to heat stress in black-boned chickens[J].Poultry Science,2014,93(1):54-62.

[15] ZHANG C,ZHAO X H,YANG L,et al.Resveratrol alleviates heat stress-induced impairment of intestinal morphology,microflora,and barrier integrity in broilers[J].Poultry Science,2017,96(12):4325-4332.

[16] ZHANG C,CHEN K K,ZHAO X H,et al.Protective effects of resveratrol against high ambient temperature-induced spleen dysplasia in broilers through modulating splenic redox status and apoptosis[J].Journal of the Science of Food and Agriculture,2018,98(14):5409-5417.

[17] 王其龙,杨景森,王丽,等.白藜芦醇改善动物生长性能和肠道健康的研究进展[J].中国饲料,2020(19):1-5. WANG Q L,YANG J S,WANG L,et al.Advances progress of resveratrol in improving the growth performance and intestinal health of animals[J].China Feed,2020(19):1-5.(in Chinese)
[18] ZHANG F,JIN C L,JIANG S G,et al.Dietary supplementation with pioglitazone hydrochloride and resveratrol improves meat quality and antioxidant capacity of broiler chickens[J].Applied Sciences,2020,10(7):2452.
[19] YU Q F,FANG C K,MA Y J,et al.Dietary resveratrol supplement improves carcass traits and meat quality of Pekin ducks[J].Poultry Science,2021,100(3):100802.
[20] CHENG K,YAN E F,SONG Z H,et al.Protective effect of resveratrol against hepatic damage induced by heat stress in a rat model is associated with the regulation of oxidative stress and inflammation[J].Journal of Thermal Biology,2019,82:70-75.
[21] 张桂枝,曹艳芳,靳双星,等.枯草芽孢杆菌发酵制剂对饲喂含AFB₁饲料肉鸡血清生化指标和肝功能的影响[J].中国家禽,2019,41(23):31-35. ZHANG G Z,CAO Y F,JIN S X,et al.Effect of Bacillus subtilis fermentation agents on the serum biochemical index and liver function of broilers fed with a diet containing AFB₁[J].China Poultry,2019,41(23):31-35.(in Chinese)
[22] HE S P,LI S,AROWOLO M A,et al.Effect of resveratrol on growth performance,rectal temperature and serum parameters of yellow-feather broilers under heat stress[J].Animal Science Journal,2019,90(3):401-411.

[23] HE S P,YU Q F,HE Y J,et al.Dietary resveratrol supplementation inhibits heat stress-induced high-activated innate immunity and inflammatory response in spleen of yellow-feather broilers[J].Poultry Science,2019,98(12):6378-6387.

[24] ATTIA Y A,ABD EL-HAMID A E H E,ABEDALLA A A,et al.Laying performance,digestibility and plasma hormones in laying hens exposed to chronic heat stress as affected by betaine,vitamin C,and/or vitamin E supplementation[J].SpringerPlus,2016,5(1):1619.
[25] COPENHAVER M,YU C Y,HOFFMAN R P.Complement components,C3 and C4,and the metabolic syndrome[J].Current Diabetes Reviews,2019,15(1):44-48.
[26] BOTTERMANN M,FOSS S,CADDY S L,et al.Complement C4 prevents viral infection through capsid inactivation[J].Cell Host & Microbe,2019,25(4):617-629.e7.

[27] LI C Y,ZHAO Y H,HAO H S,et al.Resveratrol significantly improves the fertilisation capacity of bovine sex-sorted semen by inhibiting apoptosis and lipid peroxidation[J].Scientific Reports,2018,8(1):7603.
[28] ZHA C,XIAO H,SONG B,et al.Resveratrol promotes mammary cell proliferation and antioxidation capacity during pregnancy and lactation in mice[J].Journal of Applied Microbiology,2021,130(2):450-463.

[29] ZHANG Y W,LUO H L,CHANG Y F,et al.Effects of liquorice extract on the activity and gene expression level of antioxidant enzymes in longissimus dorsi muscle of Tan lamb[J].Small Ruminant Research,2017,154:23-28.

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