Effects of Carvacrol on Growth Performance, Nutrient Apparent Digestibilities, Intestinal Digestive Enzyme Activities, Immune Organ Development and Antioxidant Capacity of Meat Rabbits

LIU Fuxin; KONG Fangen; WANG Guozhou; ZHANG Wei; LIU Shudong; CHEN Saijuan; CHEN Baojiang

doi:10.3969/j.issn.1006-267x.2022.03.047

2022 , Vol. 34 >Issue 3: 1875 - 1884

DOI: https://doi.org/10.3969/j.issn.1006-267x.2022.03.047

RESEARCH PAPER

Effects of Carvacrol on Growth Performance, Nutrient Apparent Digestibilities, Intestinal Digestive Enzyme Activities, Immune Organ Development and Antioxidant Capacity of Meat Rabbits

LIU Fuxin ,
KONG Fangen ,
WANG Guozhou ,
ZHANG Wei ,
LIU Shudong ,
CHEN Saijuan ,
CHEN Baojiang

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1. College of Animal Science and Technology, Hebei Agricultural University, Baoding 071001, China;
2. Mountainous Area Research Institute of Hebei Province, Hebei Agricultural University, Baoding 071001, China;
3. Agricultural Technology Innovation Center in Mountainous Areas of Hebei Province, Baoding 071001, China

Received date: 2021-08-18

Online published: 2022-03-14

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Abstract

This experiment was conducted to investigate the effects of carvacrol on growth performance, nutrient apparent digestibilities, intestinal digestive enzyme activities, immune organ development and antioxidant capacity of meat rabbits. One hundred and twenty healthy 35-day-old New Zealand rabbits of similar body weight were randomly allocated to 4 groups with 30 replicates per group and 1 rabbit per replicate. Rabbits in the control group were fed a basal diet, while the others in experimental groups (T1, T2 and T3 groups) were fed the basal diet supplemented with 150, 300 and 450 g/t carvacrol, respectively. The pre-feeding period lasted for 7 d followed by an experimental period of 28 d, and the digestion and metabolism test lasted for 7 d. The results showed as follows:1) compare with the control group, the average daily feed intake of T2 group was significantly decreased (P<0.05), the feed to gain ratio of T1, T2 and T3 groups was tend to decrease (P=0.056), and the mortality rate of T1, T2 and T3 groups was decreased by 3.34% (P>0.05). 2) There were no significant differences in the apparent digestibilities of dry matter (DM), crude protein (CP), gross energy (GE) and acid detergent fiber (ADF) among all groups (P>0.05). Compare with the control group, the ether extract (EE) apparent digestibility of T1, T2 and T3 groups was significantly increased (P<0.05), and the crude fiber (CF) apparent digestibility of T2 group was significantly increased (P<0.05). 3) Compare with the control group, the ileal trypsin activity of T2 and T3 groups was significantly increased (P<0.05), the cecal trypsin activity of T1, T2 and T3 groups was significantly increased (P<0.05), and the cecal lipase activity of T1 group was significantly increased (P<0.05). 4) There were no significant differences in the thymus index, liver index and spleen index among all groups (P>0.05), but the thymus index of T2 and T3 groups was increased by 50.00% and 17.27% compared with the control group. 5) Compare with the control group, the jejunal total antioxidant capacity (T-AOC) of T1 and T2 groups was significantly increased (P<0.05), the jejunal glutathione peroxidase (GSH-Px) activity of T1, T2 and T3 groups was significantly increased (P<0.05), and the liver GSH-Px activity of T1 group was significantly increased (P<0.05). In conclusion, the addition of carvacrol in the diet can reduce the diarrhea rate and feed to gain ratio of meat rabbits, increase the apparent digestibilities of EE and CF for meat rabbits, increase the activities of some digestive enzyme, increase the thymus index to a certain extent, and enhance the antioxidant capacity of jejunum and liver. Under this experimental condition, the appropriate supplemental level of carvacrol in the diet of meat rabbits is 300 g/t.

Key words： carvacrol; meat rabbits; growth performance; apparent digestibilities; digestive enzyme activities; immune organ indexes; antioxidant capacity

Cite this article

LIU Fuxin , KONG Fangen , WANG Guozhou , ZHANG Wei , LIU Shudong , CHEN Saijuan , CHEN Baojiang . Effects of Carvacrol on Growth Performance, Nutrient Apparent Digestibilities, Intestinal Digestive Enzyme Activities, Immune Organ Development and Antioxidant Capacity of Meat Rabbits[J]. Chinese Journal of Animal Nutrition, 2022 , 34(3) : 1875 -1884 . DOI: 10.3969/j.issn.1006-267x.2022.03.047

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