[1] SHEN P,ZHANG Z C,HE Y,et al.Magnolol treatment attenuates dextran sulphate sodium-induced murine experimental colitis by regulating inflammation and mucosal damage[J].Life Sciences,2018,196:69-76.
[2] PARRAY H A,LONE J,PARK J P,et al.Magnolol promotes thermogenesis and attenuates oxidative stress in 3T3-L1 adipocytes[J].Nutrition,2018,50:82-90.
[3] DING Y N,SONG Z H,LI H,et al.Honokiol ameliorates high-fat-diet-induced obesity of different sexes of mice by modulating the composition of the gut microbiota[J].Frontiers in Immunology,2019,10:2800.
[4] CHENG Y C,HUENG D Y,HUANG H Y,et al.Magnolol and honokiol exert a synergistic anti-tumor effect through autophagy and apoptosis in human glioblastomas[J].Oncotarget,2016,7(20):29116-29130.
[5] ZHANG J H,CHEN Z X,HUANG X H,et al.Insights on the multifunctional activities of magnolol[J].BioMed Research International,2019,2019:1847130.
[6] 魏泽英,王祖坤,朱培芳.云厚朴生品及3种炮制品中4种活性成分含量的HPLC-PDA测定[J].时珍国医国药,2016,27(12):2915-2919. WEI Z Y,WANG Z K,ZHU P F.Determination of four active compounds in four samples of
Magnolia rostrata W.W. Smith by HPLC-PDA[J].Lishizhen Medicine and Materia Medica Research,2016,27(12):2915-2919.(in Chinese)
[7] CHEN Y H,LIN F Y,LIU P L,et al.Antioxidative and hepatoprotective effects of magnolol on acetaminophen-induced liver damage in rats[J].Archives of Pharmacal Research,2009,32(2):221-228.
[8] HALLIWELL B.Biochemistry of oxidative stress[J].Biochemical Society Transactions,2007,35(5):1147-1150.
[9] HALLIWELL B.Tell me about free radicals,doctor:a review[J].Journal of the Royal Society of Medicine,1989,82(12):747-752.
[10] 孙雨晴.石榴皮多酚及其酶解产物的抗氧化活性和对氧化应激小鼠的保护作用研究[D]. 博士学位论文.南京:南京农业大学,2016. SUN Y Q.The antioxidant activity of pomegranate peel polyphenols and its enzymatic hydrolysates and their protective effects on oxidatively stressed mice[D].Ph.D.Thesis.Nanjing:Nanjing Agricultural University,2016.(in Chinese)
[11] KUO D H,TSAI S W,PAN M H.Magnolol blocks homocysteine-induced endothelial dysfunction in porcine coronary arteries[J].Food Chemistry,2011,127(1):135-140.
[12] ZHAO C,LIU Z Q.Comparison of antioxidant abilities of magnolol and honokiol to scavenge radicals and to protect DNA[J].Biochimie,2011,93(10):1755-1760.
[13] ZHANG W,LU D,DONG W,et al.Expression of
CYP2E1 increases oxidative stress and induces apoptosis of cardiomyocytes in transgenic mice[J].The FEBS Journal,2011,278(9):1484-1492.
[14] WANG J J,ZHAO R,LIANG J C,et al.The antidiabetic and hepatoprotective effects of magnolol on diabetic rats induced by high-fat diet and streptozotocin[J].Acta Pharmaceutica Sinica,2014,49(4):476-481.
[15] SAITO J,SHIBUYA K,NAGASE H.Anti-clastogenic effect of magnolol on benzo(a)pyrene-induced clastogenicity in mice[J].Food and Chemical Toxicology,2008,46(2):694-700.
[16] DENG Y L,LIU Y,TANG S X,et al.General machine learning model,review,and experimental-theoretic study of magnolol activity in enterotoxigenic induced oxidative stress[J].Current Topics in Medicinal Chemistry,2017,17(26):2977-2988.
[17] 庞月兰.厚朴酚与和厚朴酚抗氧化和抗腹泻功能研究[D].硕士学位论文.长沙:湖南农业大学,2010. PANG Y L.Research on the anti-oxidation and the anti-diarrhea function of magnolol and honokiol[D].Master’s Thesis.Changsha:Hunan Agricultural University,2010.(in Chinese)
[18] DE HAAN J B.Nrf2 activators as attractive therapeutics for diabetic nephropathy[J].Diabetes,2011,60(11):2683-2684.
[19] LIU X,WANG Y N,WU D,et al.Magnolol prevents acute alcoholic liver damage by activating PI3K/Nrf2/PPARγ and inhibiting NLRP3 signaling pathway[J].Frontiers in Pharmacology,2019,10:1459.
[20] 柏飞飞.黄腐酚和厚朴酚对于PC12细胞氧化损伤的保护作用及其机制的研究[D].硕士学位论文.兰州:兰州大学,2019. BAI F F.Xanthohumol analogues and magnolol alleviate oxidative stress-mediated injuries of PC12 cells[D].Master’s Thesis.Lanzhou:Lanzhou University,2019.(in Chinese)
[21] DONG L Q,ZHOU S,YANG X H,et al.Magnolol protects against oxidative stress-mediated neural cell damage by modulating mitochondrial dysfunction and PI3K/Akt signaling[J].Journal of Molecular Neuroscience,2013,50(3):469-481.
[22] YAHFOUFI N,ALSADI N,JAMBI M,et al.The immunomodulatory and anti-inflammatory role of polyphenols[J].Nutrients,2018,10(11):1618.
[23] WANG W,LIANG D J,SONG X J,et al.Magnolol inhibits the inflammatory response in mouse mammary epithelial cells and a mouse mastitis model[J].Inflammation,2015,38(1):16-26.
[24] 仲伟婷,霍美霞,郭维霄,等.厚朴酚在体外对LPS诱导细胞因子释放及ERK通路激活的影响[J].中国兽医学报,2012,32(1):79-82. ZHONG W T,HUO M X,GUO W X,et al.Magnolol inhibits LPS-induced cytokine releases and the activation of ERK pathway
in vitro[J].Chinese Journal of Veterinary Science,2012,32(1):79-82.(in Chinese)
[25] ZHANG L,WANG J,XU W,et al.Magnolol inhibits
Streptococcus suis-induced inflammation and ROS formation via TLR2/MAPK/NF-κB signaling in RAW264.7 cells[J].Polish Journal of Veterinary Sciences,2018,21(1):111-118
[26] WANG J H,SHIH K S,LIOU J P,et al.Anti-arthritic effects of magnolol in human interleukin 1β-stimulated fibroblast-like synoviocytes and in a rat arthritis model[J].PLoS One,2012,7(2):e31368.
[27] KOTA B P,HUANG T H W,ROUFOGALIS B D.An overview on biological mechanisms of PPARs[J].Pharmacological Research,2005,51(2):85-94.
[28] REDDY R C,KESHAMOUNI V G,JAIGIRDAR S H,et al.Deactivation of murine alveolar macrophages by peroxisome proliferator-activated receptor-gamyma ligands[J].American Journal of Physiology.Lung Cellular and Molecular Physiology,2004,286(3):L613-L619.
[29] REMELS A H V,LANGEN R C J,GOSKER H R,et al.PPARγ inhibits NF-κB-dependent transcriptional activation in skeletal muscle[J].American Journal of Physiology-Endocrinology and Metabolism,2009,297(1):174-183.
[30] LIN M H,CHEN M C,CHEN T H,et al.Magnolol ameliorates lipopolysaccharide-induced acute lung injury in rats through PPAR-γ-dependent inhibition of NF-κB activation[J].International Immunopharmacology,2015,28(1):270-278.
[31] LIANG X Y,XING W J,HE J X,et al.Magnolol administration in normotensive young spontaneously hypertensive rats postpones the development of hypertension:role of increased PPAR gamma,reduced TRB3 and resultant alleviative vascular insulin resistance[J].PLoS One,2015,10(3):e0120366.
[32] AGARWAL A,DAS K,LERNER N,et al.The AKT/I kappa B kinase pathway promotes angiogenic/metastatic gene expression in colorectal cancer by activating nuclear factor-kappa B and beta-catenin[J].Oncogene,2005,24(6):1021-1031.
[33] KUO D H,LAI Y S,LO C Y,et al.Inhibitory effect of magnolol on TPA-induced skin inflammation and tumor promotion in mice[J].Journal of Agricultural and Food Chemistry,2010,58(9):5777-5783.
[34] KOU D Q,JIANG Y L,QIN J H,et al.Magnolol attenuates the inflammation and apoptosis through the activation of SIRT1 in experimental stroke rats[J].Pharmacological Reports,2017,69(4):642-647.
[35] LIU Z L,ZHANG H,WANG H L,et al.Magnolol alleviates IL-1β-induced dysfunction of chondrocytes through repression of SIRT1/AMPK/PGC-1α signaling pathway[J].Journal of Interferon & Cytokine Research,2020,40(3):145-151.
[36] WU C L,WANG H Y,XU J,et al.Magnolol inhibits tumor necrosis factor-α-induced ICAM-1 expression via suppressing NF-κB and MAPK signaling pathways in human lung epithelial cells[J].Inflammation,2014,37(6):1957-1967.
[37] HUANG S H,CHEN Y,TUNG P Y,et al.Mechanisms for the magnolol-induced cell death of CGTH W-2 thyroid carcinoma cells[J].Journal of Cellular Biochemistry,2007,101(4):1011-1022.
[38] LEE D H,SZCZEPANSKI M J,LEE Y J.Magnolol induces apoptosis via inhibiting the EGFR/PI3K/Akt signaling pathway in human prostate cancer cells[J].Journal of Cellular Biochemistry,2009,106(6):1113-1122.
[39] LI M L,ZHANG F,WANG X A,et al.Magnolol inhibits growth of gallbladder cancer cells through the p53 pathway[J].Cancer Science,2015,106(10):1341-1350.
[40] ZHANG F H,REN H Y,SHEN J X,et al.Magnolol suppresses the proliferation and invasion of cholangiocarcinoma cells via inhibiting the NF-κB signaling pathway[J].Biomedicine & Pharmacotherapy,2017,94:474-480.
[41] CHEN L C,LIU Y C,LIANG Y C,et al.Magnolol inhibits human glioblastoma cell proliferation through upregulation of p21/Cip1[J].Journal of Agricultural and Food Chemistry,2009,57(16):7331-7337.
[42] KIM K M,KIM N S,KIM J,et al.Magnolol suppresses vascular endothelial growth factor-induced angiogenesis by inhibiting Ras-dependent mitogen-activated protein kinase and phosphatidylinositol 3-kinase/Akt signaling pathways[J].Nutrition and Cancer,2013,65(8):1245-1253.
[43] LIU Y,CAO W,ZHANG B,et al.The natural compound magnolol inhibits invasion and exhibits potential in human breast cancer therapy[J].Scientific Reports,2013,3(1):3098.
[44] BEHBEHANI J,SHREAZ S,IRSHAD M,et al.The natural compound magnolol affects growth,biofilm formation,and ultrastructure of oral
Candida isolates[J].Microbial Pathogenesis,2017,113:209-217.
[45] HU Y J,QIAO J L,ZHANG X,et al.Antimicrobial activity of
Magnolia officinalis extracts in vitro and its effects on the preservation of chilled mutton[J].Journal of Food Biochemistry,2011,35(2):425-441.
[46] 向华.厚朴酚抗金黄色葡萄球菌作用机制的研究[D].博士学位论文.长春:吉林大学,2010. XIANG H.Mechanism of action of magnolol against
Staphylococcus aureus[D].Ph.D.Thesis.Changchun:Jilin University,2010.(in Chinese)
[47] DONG J,DING H,LIU Y T,et al.Magnolol protects channel catfish from
Aeromonas hydrophila infection via inhibiting the expression of aerolysin[J].Veterinary Microbiology,2017,211:119-123.
[48] SAKAUE Y,DOMON H,ODA M,et al.Anti-biofilm and bactericidal effects of magnolia bark-derived magnolol and honokiol on
Streptococcus mutans[J].Microbiology and Immunology,2016,60(1):10-16.
[49] LIN Q,ZHAO J F,XIE K,et al.Magnolol additive as a replacer of antibiotic enhances the growth performance of Linwu ducks[J].Animal Nutrition,2017,3(2):132-138.
[50] 程迪,王佳丽,周子涛,等.厚朴总酚对肉仔鸡生长性能,免疫功能及抗氧化能力的影响[J].饲料研究,2015(15):1-4,38. CHENG D,WANG J L,ZHOU Z T,et al.Effects of total phenols of
Magnolia officinalis on growth performance,immune function and antioxidant capacity of broilers[J].Feed Research,2015(15):1-4,38.(in Chinese)
[51] 曹蓉.厚朴总酚对黄羽肉鸡生产性能、抗氧化及肠道功能的影响[D].硕士学位论文.长沙:湖南农业大学,2015. CAO R.Effects of total phenols from
Magnolia officinalis on the growth performance,antioxidant ability and intestinal function of yellow broilers[D].Master’s Thesis.Changsha:Hunan Agricultural University,2015.(in Chinese)
[52] CHEN F,ZHANG H,DU E C,et al.Effects of magnolol on egg production,egg quality,antioxidant capacity,and intestinal health of laying hens in the late phase of the laying cycle[J].Poultry Science,2021,100(2):835-843.
[53] CHEN F,ZHANG H,DU E C,et al.Supplemental magnolol or honokiol attenuates adverse effects in broilers infected with
Salmonella pullorum by modulating mucosal gene expression and the gut microbiota[J].Journal of Animal Science and Biotechnology,2021,12(1):87.
[54] LIN Q,PENG S M,LI Y H,et al.Magnolol additive improves carcass and meat quality of
Linwu ducks by modulating antioxidative status[J].Animal Science Journal,2020,91(1):e13301.
