Research Progress on Physiological Function of Polyamines and Its Mechanism

YIN Yunju; LI Fengna; LI Keke; CHEN Qinghua

doi:10.3969/j.issn.1006-267x.2022.04.013

Chinese Journal of Animal Nutrition >

2022 , Vol. 34 >Issue 4: 2167 - 2176

DOI: https://doi.org/10.3969/j.issn.1006-267x.2022.04.013

Research Progress on Physiological Function of Polyamines and Its Mechanism

YIN Yunju ,
LI Fengna ,
LI Keke ,
CHEN Qinghua

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1. College of Animal Science and Technology, Hunan Agricultural University, Changsha 410128, China;
2. Hunan Provincial Key Laboratory of Animal Nutrition Physiology and Metabolic Process, Key Laboratory of Agricultural Processes in Subtropical Region, Institute of Subtropical Agriculture, Chinese Academy of Sciences, Changsha 410125, China;
3. Henan Golden Lily Biotechnology Co., Ltd., Tangyin 456150, China

Received date: 2021-09-16

Online published: 2022-04-14

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Abstract

Polyamines commonly exist in animal and plant cells and are widely involved in physiological and pathological processes in organisms. There are three sources of polyamines in animal body:food intake, gut microorganism synthesis and cell synthesis, among which dietary polyamines are the main source. Polyamines have important effects on animal health, including intestinal maturation and differentiation and development of the immune system. In addition, the antioxidant and anti-inflammatory effects of polyamines also play an important role in the prevention of chronic diseases such as cardiovascular disease. In this paper, the physiological function and mechanism of polyamines were discussed from the aspects of the regulation of intestinal epithelial cell migration, immune function, oxidative stress state and myocardial cell apoptosis by polyamines. Meanwhile, the application of polyamines in livestock and poultry production was also described, in order to provide reference for the development and application of polyamines in livestock and poultry feed additives.

Key words： polyamine; cell apoptosis; intestine; oxidative stress

Cite this article

YIN Yunju , LI Fengna , LI Keke , CHEN Qinghua . Research Progress on Physiological Function of Polyamines and Its Mechanism[J]. Chinese Journal of Animal Nutrition, 2022 , 34(4) : 2167 -2176 . DOI: 10.3969/j.issn.1006-267x.2022.04.013

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