REVIEW

Research Progress of Dietary Plant miRNA in Cross-Kingdom Regulation on Animal Health

  • LI Meng ,
  • PENG Han ,
  • PENG Yongjia ,
  • ZHANG Jin
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  • College of Biological Chemical Sciences and Engineering, Jiaxing University, Jiaxing 314001, China

Received date: 2021-10-17

  Online published: 2022-05-14

Abstract

Nutrients in food are generally considered important animal nutrition-related gene expression regulators. In recent years, it has been found that food-derived dietary miRNA could serve as a novel functional component that plays a regulatory role in the animal body. Over the past decade, evidence has indicated that plant miRNA were absorbed by feeding, participated in the regulation of gene expression, and impacted animal physiological processes and the development of animal diseases. At present, there is no systematic and comprehensive summary of plant miRNA transport pathways and regulatory functions in the animal. This review summarizes and analyses the research progress of plant miRNA in terms of cross-kingdom stability, transport mode, absorption regulation, mechanism of function, and metabolism. It provides a new perspective for exploring the relationship between plant miRNA and animal health. Our review also forecasts the application prospect of plant miRNA in animal disease and production and provides a reference for plant miRNA development and utilization.

Cite this article

LI Meng , PENG Han , PENG Yongjia , ZHANG Jin . Research Progress of Dietary Plant miRNA in Cross-Kingdom Regulation on Animal Health[J]. Chinese Journal of Animal Nutrition, 2022 , 34(5) : 2732 -2740 . DOI: 10.3969/j.issn.1006-267x.2022.05.002

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