REVIEW

Mechanism of 3-Nitroxypropanol in Reducing Methane Emission from Ruminants' Rumen and Its Application Prospect in Production

  • ZHOU Xiaokang ,
  • LI Hao ,
  • ZHANG Liyang ,
  • GAO Tengyun
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  • Henan International Joint Laboratory of Nutrition Regulation and Ecological Raising of Domestic Animal, College of Animal Science and Technology, Henan Agricultural University, Zhengzhou 450002, China

Received date: 2021-10-12

  Online published: 2022-06-14

Abstract

Methane emitted from ruminant gastrointestinal tract is considered as an important source of global greenhouse gas emission to a certain extent, and it also represents the loss of dietary energy. It was found that the nitroester group in 3-nitroxypropanol (3-NOP) can selectively combine with methyl coenzyme M reductase, and inactivate the enzyme by temporarily oxidizing nickel ions from +1 to +2 at the active site, thus inhibiting the last step in the process of methane generation continuously inhibiting methane generation, and having no effect on the health of ruminants. In this paper, the research on 3-NOP, a specific inhibitor of methane production, was reviewed, aiming at clarifying the internal mechanism of methane production inhibition and providing substantial theoretical support and reference for ruminant production and the application prospect of 3-NOP.

Cite this article

ZHOU Xiaokang , LI Hao , ZHANG Liyang , GAO Tengyun . Mechanism of 3-Nitroxypropanol in Reducing Methane Emission from Ruminants' Rumen and Its Application Prospect in Production[J]. Chinese Journal of Animal Nutrition, 2022 , 34(6) : 3454 -3460 . DOI: 10.3969/j.issn.1006-267x.2022.06.007

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