RESEARCH PAPER

Effects of Dietary Quercetagetin on Growth Performance, Nutrient Apparent Digestibility and Antioxidant Capacity of Broilers

  • ZHENG Xu ,
  • RAO Zhiyong ,
  • MENG Chunyan ,
  • LI Yue ,
  • ZHANG Wei ,
  • GUO Yongpeng ,
  • WU Di ,
  • WANG Zhixiang
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  • 1. College of Animal Science and Technology, Henan Agricultural University, Zhengzhou 450002, China;
    2. Chenguang Biological Technology Group Co., Ltd., Handan 057250, China

Received date: 2022-01-08

  Online published: 2022-07-14

Abstract

This study was conducted to evaluate the effects of dietary quercetagetin on growth performance, nutrient apparent digestibility and antioxidant capacity of broilers. Four hundred and eighty healthy Arbor Acres (AA) broilers of 1-day-old were randomly divided into 4 groups with 6 replicates per group and 20 broilers per replicate. Broilers in the control group were fed a basal diet, and those in the experimental groups were fed the basal diets supplemented with 10, 50 and 100 mg/kg quercetagetin, respectively. The experiment lasted for 42 days consisting of 2 stages of 1 to 21 and 22 to 42 days of age. The results showed as follows:1) compared with the control group, dietary 50 and 100 mg/kg quercetagetin significantly increased the body weight of broilers at 42 days of age and the average daily gain (ADG) from 1 to 42 days of age (P<0.05), and significantly decreased the ratio of feed to gain (F/G) from 1 to 21, 22 to 42 and 1 to 42 days of age as well as the average daily feed intake (ADFI) from 1 to 42 days of age (P<0.05). 2) Compared with the control group, dietary 10 and 50 mg/kg quercetagetin significantly increased the apparent digestibility of ether extract and crude protein of broilers, respectively (P<0.05). 3) Compared with the control group, dietary 50 and 100 mg/kg quercetagetin significantly increased the serum glutathione peroxidase (GSH-Px) activity of broilers at 21 and 42 days of age (P<0.05); dietary 10 and 50 mg/kg quercetagetin significantly increased the liver GSH-Px activity of broilers (P<0.05); dietary 10 mg/kg quercetagetin significantly increased the serum GSH-Px activity of broilers at 42 days of age, and total antioxidant capacity (T-AOC) and superoxide dismutase (SOD) activity in breast muscle (P<0.05). 4) Compared with the control group, dietary 50 mg/kg quercetin significantly increased the mRNA relative expression levels of nuclear factor E2-related factor 2 (Nrf2) in liver and glutamate cysteine ligase regulatory subunit (GCLm) in breast muscle of broilers (P<0.05); dietary 10, 50 and 100 mg/kg quercetagetin significantly increased the mRNA relative expression levels of glutathione peroxidase 1 (GPX1) in liver and breast muscle and Nrf2 in breast muscle of broilers (P<0.05). In conclusion, the appropriate level of dietary quercetagetin can improve the growth performance, increase the apparent digestibility of crude protein and ether extract of broilers, and enhance the antioxidant capacity of broilers by up-regulating Nrf2/antioxidant component (ARE) signaling pathway related genes expression. Under the experimental conditions, the regression analysis of growth performance of broilers and quercetagetin supplemental level shows that the optimal supplemental level of quercetagetin is 64.91 to 68.42 mg/kg.

Cite this article

ZHENG Xu , RAO Zhiyong , MENG Chunyan , LI Yue , ZHANG Wei , GUO Yongpeng , WU Di , WANG Zhixiang . Effects of Dietary Quercetagetin on Growth Performance, Nutrient Apparent Digestibility and Antioxidant Capacity of Broilers[J]. Chinese Journal of Animal Nutrition, 2022 , 34(7) : 4271 -4282 . DOI: 10.3969/j.issn.1006-267x.2022.07.019

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