Effects of Dietary Postbiotics on Growth Performance, Diarrhea Incidence, Antioxidant Capacity and Fecal Microbiome of Weaned Piglets

YIN Chenggang; GAO Ge; SHANG Tan; LI Xilong; JIANG Xianren

doi:10.3969/j.issn.1006-267x.2022.08.019

2022 , Vol. 34 >Issue 8: 4932 - 4943

DOI: https://doi.org/10.3969/j.issn.1006-267x.2022.08.019

RESEARCH PAPER

Effects of Dietary Postbiotics on Growth Performance, Diarrhea Incidence, Antioxidant Capacity and Fecal Microbiome of Weaned Piglets

YIN Chenggang ,
GAO Ge ,
SHANG Tan ,
LI Xilong ,
JIANG Xianren

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1. Key Laboratory of Feed Biotechnology of Ministry of Agriculture, Institute of Feed Research, Chinese Academy of Agricultural Sciences, Beijing 100081, China;
2. Cytozyme (Beijing) Agricultural Technology Co., Ltd., Beijing 100027, China

Received date: 2022-01-29

Online published: 2022-08-11

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Abstract

This experiment was conducted to investigate the effects of dietary postbiotics on growth performance, diarrhea incidence, antioxidant capacity and fecal microbiome of weaned piglets. Seventy-five 23-day-old "Duroc×Landrace×Yorkshire" hybrid weaned castrated barrows with initial body weight of (6.18±0.21) kg were randomly divided into 3 groups with 5 replicates in each group and 5 piglets in each replicate. Piglets in the negative control group (NC group) were fed a basal diet without antibiotics and zinc oxide, piglets in the positive control group (PC group) were fed the basal diet+zinc oxide (supplemented with 2 kg/t during days 1 to 14 and no supplemented during days 15 to 42), piglets in the postbiotics group (PB group) were fed a basal diet+postbiotics (supplemented with 4 kg/t during days 1 to 14 and supplemented with 2 kg/t during days 15 to 42). The experiment period was 42 days. The results showed as follows: 1) the body weight on day 28 of PC group was significantly lower than that of NC group and PB group (P<0.05), and the average daily gain (ADG) and average daily food intake (ADFI) during days 15 to 28 were significantly lower than that of NC group and PB group (P<0.01). The diarrhea incidence during days 1 to 14 of PC group and PB group was significantly lower than that of NC group (P<0.01). 2) On days 14 and days 42, the activities of superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) in plasma of PC group and PB group were significantly higher than those of NC group (P<0.01), the plasma malondialdehyde (MDA) content of PB group was significantly lower than that of NC group (P<0.05 or P<0.01), and the plasma immunoglobulin A (IgA) content of PB group was significantly higher than that of NC group (P<0.01). 3) The Shannon index of PC group and PB group was significantly higher than that of NC group (P<0.01), and the Simpson index of PC group and PB group was significantly lower than that of NC group (P<0.05). 4) The fecal Lactobacillus relative abundance of NC group and PB group was significantly higher than that of PC group (P<0.01), the fecal Clostridium_sensu_stricto_1 relative abundance of PC group was significantly higher than that of NC group and PB group (P<0.01). In conclusion, dietary postbiotics can reduce the diarrhea incidence of weaned piglets in early nursery stage, improve the antioxidant capacity and immune function, enrich fecal microbiome diversity, and maintain the number of beneficial bacteria.

Key words： postbiotics; weaned piglets; antioxidant capacity; fecal microbiome

Cite this article

YIN Chenggang , GAO Ge , SHANG Tan , LI Xilong , JIANG Xianren . Effects of Dietary Postbiotics on Growth Performance, Diarrhea Incidence, Antioxidant Capacity and Fecal Microbiome of Weaned Piglets[J]. Chinese Journal of Animal Nutrition, 2022 , 34(8) : 4932 -4943 . DOI: 10.3969/j.issn.1006-267x.2022.08.019

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