Effects of N-Carbamylglutamate on Lactation Performance and Plateau Adaptability of Holstein&#215;Tibet Hybrid Cows

JIANG Aoyu; BASANG Zhuzha; LI Bin; WU Yicheng; PENG Jinfen; LYU Xiaokang; LIU Zixin; HUANG Ximei; ZHOU Chuanshe; CHEN Liang; TAN Zhiliang

doi:10.3969/j.issn.1006-267x.2022.09.042

Chinese Journal of Animal Nutrition >

2022 , Vol. 34 >Issue 9: 5879 - 5890

DOI: https://doi.org/10.3969/j.issn.1006-267x.2022.09.042

RESEARCH PAPER

Effects of N-Carbamylglutamate on Lactation Performance and Plateau Adaptability of Holstein×Tibet Hybrid Cows

JIANG Aoyu ,
BASANG Zhuzha ,
LI Bin ,
WU Yicheng ,
PENG Jinfen ,
LYU Xiaokang ,
LIU Zixin ,
HUANG Ximei ,
ZHOU Chuanshe ,
CHEN Liang ,
TAN Zhiliang

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1. Hunan Provincial Key Laboratory of Animal Nutrition Physiology and Metabolic Process, National Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production, CAS Key Laboratory for Agro-Ecological Processes in Subtropical Region, Institute of Subtropical Agriculture, Chinese Academy of Sciences, Changsha 410125, China;
2. University of Chinese Academy of Sciences, Beijing 100049, China;
3. Institute of Animal Science, Tibet Academy of Agricultural and Animal Husbandry Sciences, Lhasa 850000, China;
4. Zhongshan Nenghe Biotechnology Co., Ltd., Zhongshan 528415, China;
5. Rural Revitalization Strategy Research Institute, Shenyang Agricultural University, Shenyang 110866, China

Received date: 2022-03-31

Online published: 2022-10-17

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Abstract

This experiment was conducted to investigate the effects of N-carbamyl glutamate (NCG) fed at high altitude and low oxygen environment on nutrient apparent digestibility, lactation performance, rumen fermentation parameters, serum biochemistry indexes, antioxidant indexes and anti-altitude response indexes of dairy cows. Twenty hybrid cows of Holstein dairy cow×Tibetan cattle cross third generation dairy cows in pre-lactation with similar parity, body weight, milk yield and physical condition scores were randomly divided into two groups of 10 cows each. The control group was fed a basic diet (CON group), and the NCG group was added 20 g/(head·d) NCG to the basic diet. The experiment lasted for 45 d, including 15 d for pre-test and 30 d for formal test. The results showed as follows:1) the 4% fat corrected milk and feed conversion rate in NCG group were 39.35% and 54.16% higher than those in CON group, respectively (P<0.05). 2) Compared with CON group, the milk yield and milk total solid content of NCG group were significantly increased (P<0.05), milk urea nitrogen content was decreased by 19.61% (P=0.13), and milk fat percentage was increased by 8.53% (P=0.13). 3) Compared with CON group, ammoniacal nitrogen (NH₃-N) content in rumen fluid of NCG group was decreased by 38.11% (P<0.05), and microbial protein content was increased by 12.43% (P<0.05), and there was an increasing trend in acetic/propionic (P=0.07). 4) The total cholesterol content and glutamic-pyruvic transaminase activity of NCG group were significantly lower than those in CON group (P<0.05), and the content of triglyceride was significantly increased compared with CON group (P<0.05). 5) Compared with CON group, the glutathione peroxidase, superoxide dismutase activity and total antioxidant capacity of NCG group were significantly increased (P<0.05), and the contents of malondialdehyde and reactive oxygen species (P<0.05) were significantly decreased. 6) Dietary NCG supplementation could significantly increase the contents of vascular endothelial growth factor and nitric oxide (P<0.05), as well as activity of endothelial nitric oxide synthase and inducible nitric oxide synthase in serum (P<0.05). It is concluded that dietary NCG supplementation can enhance lactation performance, antioxidant and anti-altitude response capacity, and improve liver metabolism and nitrogen cycling of dairy cows in high altitude and low oxygen environment.

Key words： N-carbamyl glutamate; Holstein×Tibet hybrid cows; milk performance; oxidation resistance; anti-altitude response

Cite this article

JIANG Aoyu , BASANG Zhuzha , LI Bin , WU Yicheng , PENG Jinfen , LYU Xiaokang , LIU Zixin , HUANG Ximei , ZHOU Chuanshe , CHEN Liang , TAN Zhiliang . Effects of N-Carbamylglutamate on Lactation Performance and Plateau Adaptability of Holstein×Tibet Hybrid Cows[J]. Chinese Journal of Animal Nutrition, 2022 , 34(9) : 5879 -5890 . DOI: 10.3969/j.issn.1006-267x.2022.09.042

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