SPECIAL COLUMN:RESEARCH PROGRESS ON FEED NUTRITION

Epigenetic and Transcriptional Regulation of N6-Methyladenosine RNA Methylation in Animal Nutritional Physiology and Metabolism

  • ZHONG Xiang ,
  • WANG Huan ,
  • WANG Tian
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  • College of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China

Received date: 2022-08-01

  Online published: 2022-10-17

Abstract

In recent years, epigenetic transcriptomics has opened a new chapter in life science and human medicine research. As the main aspects of the epigenetic transcriptome, N6-methyladenine (m6A) plays an important regulatory role in animal phenotypes and traits. In addition, nutrition is a key factor affecting animal phenotypes and traits, which is closely related to epigenetics. Therefore, it is worth exploring how m6A RNA methylation dynamically regulates nutrient metabolism and the effects of nutrient metabolism on m6A RNA methylation. This review summarized the molecular basis of m6A RNA methylation and its interactions with carbohydrate metabolism, lipid metabolism, ion metabolism and microbiota, aiming to provide important support for the profound understanding of the theoretical basis of animal nutrition physiology and metabolism and the development of a new theoretical system of animal nutrition, and provide new ideas for the development of animal husbandry in the future.

Cite this article

ZHONG Xiang , WANG Huan , WANG Tian . Epigenetic and Transcriptional Regulation of N6-Methyladenosine RNA Methylation in Animal Nutritional Physiology and Metabolism[J]. Chinese Journal of Animal Nutrition, 2022 , 34(10) : 6257 -6264 . DOI: 10.3969/j.issn.1006-267x.2022.10.017

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