RESEARCH PAPER

Effects of Combined Yeast and Bacillus coagulans Fermentation Culture on Growth Performance, Nutrient Apparent Digestibility, Immunity and Antioxidant Capacity of Rex Rabbits

  • WANG Guozhou ,
  • WU Fengyang ,
  • YU Zhikai ,
  • KONG Lingchang ,
  • WANG Junfeng ,
  • LIU Yajuan ,
  • CHEN Baojiang
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  • 1. College of Animal Science and Technology, Hebei Agricultural University, Baoding 071001, China;
    2. Mountainous Area Research Institute of Hebei Province, Hebei Agricultural University, Baoding 071001, China;
    3. National Engineering Research Center for Agriculture in Northern Mountainous Areas, Baoding 071001, China;
    4. Jiangsu Yinong Bioengineering Co., Ltd., Suqian 223600, China

Received date: 2022-04-15

  Online published: 2022-10-17

Abstract

This experiment was conducted to investigate the effects of different supplemental levels of combined yeast and Bacillus coagulans fermentation culture on growth performance, nutrient apparent digestibility, immunity and antioxidant capacity of Rex rabbits. A total of 160 healthy Rex rabbits at 35-day-old with similar body weight were randomly allocated to 4 groups with 8 replicates per group and 5 rabbits per replicate. Rex rabbits in the control group was fed a basal diet, while the others in experimental groups were fed experimental diets supplemented with 0.01%, 0.02% and 0.04% combined yeast and Bacillus coagulans fermentation culture based on the basal diet, respectively. The pretrial period lasted for 7 days and formal period lasted for 56 days. The results showed as follows: 1) compared with the control group, dietary supplemented with different levels of combined yeast and Bacillus coagulans fermentation culture significantly increased average daily gain (P < 0.05), trended to increase the final body weight and decrease the ratio of feed to gain (0.05≤P < 0.10), and decreased diarrhea frequency (P > 0.05). 2) Compared with the control group, the calcium (Ca) apparent digestibility of 0.01% and 0.02% added groups was significantly increased (P < 0.05), the dry matter (DM), gross energy (GE), crude protein (CP) and Ca apparent digestibility of 0.04% added group was significantly increased (P < 0.05). 3) There were no significant differences in intestinal digestive enzyme activities and immune organ indexes among all groups (P > 0.05). 4) Compared with the control group, the serum immunoglobulin A (IgA) and interleukin-4 (IL-4) contents of each added groups were significantly increased (P < 0.05), and the serum immunoglobulin G (IgG) content of 0.04% added group trended to increase (0.05≤P < 0.10), while there was no significant difference in serum immunoglobulin M (IgM) content among all groups (P > 0.05). 5) Compared with the control group, there were no significant differences in serum, liver and jejunal glutathione peroxidase (GSH-Px), superoxide dismutase (SOD) activities and total antioxidant capacity (T-AOC) in each added groups (P > 0.05), and the jejunal malondialdehyde (MDA) content of 0.02% and 0.04% added groups tended to decrease (0.05≤P < 0.10). In summary, dietary supplemented with combined yeast and Bacillus coagulans fermentation culture can improve the growth performance, increase the apparent digestibility of nutrients and enhance immunity of Rex rabbits. Comprehensive analysis, the appropriate supplemental level of combined yeast and Bacillus coagulans fermentation culture in the diet for Rex rabbits is 0.02% to 0.04%.

Cite this article

WANG Guozhou , WU Fengyang , YU Zhikai , KONG Lingchang , WANG Junfeng , LIU Yajuan , CHEN Baojiang . Effects of Combined Yeast and Bacillus coagulans Fermentation Culture on Growth Performance, Nutrient Apparent Digestibility, Immunity and Antioxidant Capacity of Rex Rabbits[J]. Chinese Journal of Animal Nutrition, 2022 , 34(10) : 6665 -6676 . DOI: 10.3969/j.issn.1006-267x.2022.10.059

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