[1] 任伟忠.奶牛干奶前期饲喂不同粗饲料日粮对其生产性能、血液指标及瘤胃发酵的影响[D].硕士学位论文.保定:河北农业大学, 2019. REN W Z.Effects of different roughage diets fed to the dry cows during the first phase of the dry period on its performance, blood indexes and rumen fermentation[D].Master's Thesis.Baoding:Hebei Agricultural University, 2019.(in Chinese)
[2] 欧四海, 冯建丽, 付云宝, 等.德系弗莱维赫牛与高产荷斯坦奶牛杂交一代生产性能研究[J].中国乳业, 2019(10):55-57. OU S H, FENG J L, FU Y B, et al.Study on the production performance of the first generation of German Fleivich cattle and high-yield Holstein cows[J].China Dairy, 2019(10):55-57.(in Chinese)
[3] 姜晓鹃.鲁西牛、中国西门塔尔牛和荷斯坦牛的经济效益分析[D].硕士学位论文.北京:中国农业科学院, 2011. JIANG X J.The economic benefit analysis of
Luxi, Chinese Simmental and Holstein[D].Master's Thesis.Beijing:Chinese Academy of Agricultural Sciences, 2011.(in Chinese)
[4] DE LA TORRE-SANTOS S, ROYO L J, MARTÍNEZ-FERNÁNDEZ A, et al.The mode of grass supply to dairy cows impacts on fatty acid and antioxidant profile of milk[J].Foods, 2020, 9(9):1256.
[5] DAVIS H, STERGIADIS S, CHATZIDIMITRIOU E, et al.Meeting breeding potential in organic and low-input dairy farming[J].Frontiers in Veterinary Science, 2020, 7:544149.
[6] SUN H Z, WANG D M, WANG B, et al.Metabolomics of four biofluids from dairy cows:potential biomarkers for milk production and quality[J].Journal of Proteome Research, 2015, 14(2):1287-1298.
[7] HUMER E, KRÖGER I, NEUBAUER V, et al.Supplementing phytogenic compounds or autolyzed yeast modulates ruminal biogenic amines and plasma metabolome in dry cows experiencing subacute ruminal acidosis[J].Journal of Dairy Science, 2018, 101(10):9559-9574.
[8] TANG C H, ZHANG K, ZHAN T F, et al.Metabolic characterization of dairy cows treated with gossypol by blood biochemistry and body fluid untargeted metabolome analyses[J].Journal of Agricultural and Food Chemistry, 2017, 65(42):9369-9378.
[9] AMETAJ B N, ZEBELI Q, SALEEM F, et al.Metabolomics reveals unhealthy alterations in rumen metabolism with increased proportion of cereal grain in the diet of dairy cows[J].Metabolomics, 2010, 6(4):583-594.
[10] MAO S Y, HUO W J, ZHU W Y.Microbiome-metabolome analysis reveals unhealthy alterations in the composition and metabolism of ruminal microbiota with increasing dietary grain in a goat model[J].Environmental Microbiology, 2016, 18(2):525-541.
[11] ZHAO S, ZHAO J, BU D, et al.Metabolomics analysis reveals large effect of roughage types on rumen microbial metabolic profile in dairy cows[J].Letters in Applied Microbiology, 2014, 59(1):79-85.
[12] SUN L W, ZHANG H Y, WU L, et al.(1)H-nuclear magnetic resonance-based plasma metabolic profiling of dairy cows with clinical and subclinical ketosis[J].Journal of Dairy Science, 2014, 97(3):1552-1562.
[13] LI T G, APTE U.Bile acid metabolism and signaling in cholestasis, inflammation, and cancer[J].Advances in Pharmacology, 2015, 74:263-302.
[14] BATTA A K, SALEN G, ARORA R, et al.Side chain conjugation prevents bacterial 7-dehydroxylation of bile acids[J].Journal of Biological Chemistry, 1990, 265(19):10925-10928.
[15] RIDLON J M, KANG D J, HYLEMON P B.Bile salt biotransformations by human intestinal bacteria[J].Journal of Lipid Research, 2006, 47(2):241-259.
[16] PACÍFICO C, STAUDER A, REISINGER N, et al.Distinct serum metabolomic signatures of multiparous and primiparous dairy cows switched from a moderate to high-grain diet during early lactation[J].Metabolomics, 2020, 16(9):96.
[17] SHERIHA G M, WALLER G R, CHAN T, et al.Composition of bile acids in ruminants[J].Lipids, 1968, 3(1):72-78.
[18] 刘艳利, 孙文强, 韩迪, 等.基于GC-MS代谢组学技术对叶酸调控鸡原代肝细胞代谢的研究[J].畜牧兽医学报, 2018, 49(9):1919-1927. LIU Y L, SUN W Q, HAN D, et al.The study on folic acid regulating metabolism of chicken primary hepatocytes by GC-MS metabolomics[J].Acta Veterinaria et Zootechnica Sinica, 2018, 49(9):1919-1927.(in Chinese)
[19] ZHAO M, YUAN M M, YUAN L, et al.Chronic folate deficiency induces glucose and lipid metabolism disorders and subsequent cognitive dysfunction in mice[J].PLoS One, 2018, 13(8):e0202910.
[20] 杨鑫, 汪水平, 谭支良, 等.胆汁酸菌群修饰介导肠道黏膜免疫的研究进展[J].动物营养学报, 2021, 33(7):3702-3712. YANG X, WANG S P, TAN Z L, et al.Gut microbiota-dominated bioconversion of bile acids on intestinal mucosal immunity:a systemic review[J].Chinese Journal of Animal Nutrition, 2021, 33(7):3702-3712.(in Chinese)
[21] DEVLIN A S, FISCHBACH M A.A biosynthetic pathway for a prominent class of microbiota-derived bile acids[J].Nature Chemical Biology, 2015, 11(9):685-690.
[22] JAROCKI P, TARGOÑSKI Z.Genetic diversity of bile salt hydrolases among human intestinal bifidobacteria[J].Current Microbiology, 2013, 67(3):286-292.
[23] SAYIN S I, WAHLSTRÖM A, FELIN J, et al.Gut microbiota regulates bile acid metabolism by reducing the levels of tauro-beta-muricholic acid, a naturally occurring FXR antagonist[J].Cell Metabolism, 2013, 17(2):225-235.
[24] 杨汉博.胆汁酸——脂肪消化促进剂[J].饲料广角, 2008(11):49-50. YANG H B.Bile acid-fat digestion promoter[J].Feed China, 2008(11):49-50.(in Chinese)
[25] 汪悦, 王炳, 童津津, 等.牛奶微生物群落与奶牛乳腺健康和犊牛胃肠道发育的关系[J].动物营养学报, 2018, 30(2):458-467. WANG Y, WANG B, TONG J J, et al.Relationship between milk microbial community and mammary gland health of dairy cows as well as gastrointestinal development of calves[J].Chinese Journal of Animal Nutrition, 2018, 30(2):458-467.(in Chinese)
[26] MALLOY C R, SHERRY A D, JEFFREY F M.Evaluation of carbon flux and substrate selection through alternate pathways involving the citric acid cycle of the heart by 13C NMR spectroscopy[J].The Journal of Biological Chemistry, 1988, 263(15):6964-6971.
[27] HE W H, MIAO F J P, LIN D C H, et al.Citric acid cycle intermediates as ligands for orphan G-protein-coupled receptors[J].Nature, 2004, 429(6988):188-193.
[28] SUN H Z, SHI K, WU X H, et al.Lactation-related metabolic mechanism investigated based on mammary gland metabolomics and 4 biofluids' metabolomics relationships in dairy cows[J].BMC Genomics, 2017, 18(1):936.
[29] XU K, LIU H N, BAI M M, et al.Redox properties of tryptophan metabolism and the concept of tryptophan use in pregnancy[J].International Journal of Molecular Sciences, 2017, 18(7):1595.
[30] VILJOEN M, SWANEPOEL A, BIPATH P.Antidepressants may lead to a decrease in niacin and NAD in patients with poor dietary intake[J].Medical Hypotheses, 2015, 84(3):178-182.
[31] 魏筱诗, 姚军虎, 王翀.烟酸和烟酰胺在反刍动物机体代谢及生产研究中的异同性[J].动物营养学报, 2020, 32(12):5509-5515. WEI X S, YAO J H, WANG C.Similarities and differences of niacin and niacinamide in study on metabolism and production of ruminant[J].Chinese Journal of Animal Nutrition, 2020, 32(12):5509-5515.(in Chinese)
[32] WEI X S, CAI C J, HE J J, et al.Effects of biotin and nicotinamide supplementation on glucose and lipid metabolism and milk production of transition dairy cows[J].Animal Feed Science and Technology, 2018, 237:106-117.
[33] DESLANDES B, GARIÉPY C, HOUDE A.Review of microbiological and biochemical effects of skatole on animal production[J].Livestock Production Science, 2001, 71(2/3):193-200.
[34] 孟德超.集约化牛场体况管理对泌乳奶牛代谢、生产性能和健康的影响[D].硕士学位论文.大庆:黑龙江八一农垦大学, 2021. MENG D C.Effects of intensive cattle farm body condition management on metabolism, production performance and health of lactating dairy cows[D].Master's Thesis.Daqing:Heilongjiang Bayi Agricultural University, 2021.(in Chinese)
[35] 朱玉哲.泌乳量与日粮能量水平对泌乳奶牛生殖机能的影响[D].硕士学位论文.大庆:黑龙江八一农垦大学, 2009. ZHU Y Z.The effect of milk yield and dietary energy levels on reproductive function of lactating cows[D].Master's Thesis.Daqing:Heilongjiang Bayi Agricultural University, 2009.(in Chinese)
[36] 许丽惠, 谢丽曲, 林丽花.叶酸的研究进展[J].福建畜牧兽医, 2013, 35(2):34-36. XU L H, XIE L Q, LIN L H.Research progress of folic acid[J].Fujian Journal of Animal Husbandry and Veterinary Medicine, 2013, 35(2):34-36.(in Chinese)
[37] BÄSSLER K H.Enzymatic effects of folic acid and vitamin B
12[J].International Journal for Vitamin and Nutrition Research, 1997, 67(5):385-388.
[38] 薛良敏, 王锰, 刘俊义, 等.新型叶酸拮抗剂吡啶并嘌呤衍生物的环合反应研究[J].化学通报, 2018, 81(7):653-656. XUE L M, WANG M, LIU J Y, et al.Cyclization reaction of pyridanopurine derivatives as novel antifolate[J].Chemistry, 2018, 81(7):653-656.(in Chinese)
[39] 方芳, 薛良敏, 丛婧, 等.2-位或4-位取代吡啶并嘧啶类非经典叶酸拮抗剂的合成及抗肿瘤活性[J].高等学校化学学报, 2019, 40(10):2111-2120. FANG F, XUE L M, CONG J, et al.Synthesis and anti-tumor activity evaluation of a series of 2-or 4-substituted pyrido[3, 2-d] pyrimidines as nonclassical antifolates[J].Chemical Journal of Chinese Universities, 2019, 40(10):2111-2120.(in Chinese)
